Testing of four-sample pools offers resource optimization without compromising diagnostic performance of real time reverse transcriptase-PCR assay for COVID-194개 샘플 풀의 테스트는 COVID-19에 대한 실시간 역전사효소-PCR 분석의 진단 성능을 손상시키지 않으면서 리소스 최적화를 제공합니다.Research Article Published on 2021-05-182022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] Background Prevalence Complete Concordance consecutive sample COVID-19 COVID-19 diagnosis COVID-19 pandemic determine diagnostic diagnostic test Disease prevalence evaluated examined false negativity gold gold standard infected individuals Isolation Laboratory Negative predictive value observation offer positive positive sample Predictive value Prevalence proportion real time recorded reduction in resource reverse transcriptase reverse transcriptase PCR rRT-PCR SARS-CoV-2 infected individual SARS-CoV-2 infected individuals Testing utility while [DOI] 10.1371/journal.pone.0251891 PMC 바로가기 [Article Type] Research Article
Exploring antibody repurposing for COVID-19: beyond presumed roles of therapeutic antibodiesCOVID-19에 대한 항체 용도 변경 탐색: 추정되는 치료 항체의 역할을 넘어서Article Published on 2021-05-132022-08-31 Journal: Scientific Reports [Category] SARS, 신약개발, 임상, 진단, [키워드] activity antibodies antibody bypassing clinical trials Computational biology and bioinformatics COVID-19 CTLA4 diagnostic diagnostic test drug dual effective elevated epitope evaluated IL17A immunology Immunosuppression in silico Infection Interaction Ipilimumab medical condition monoclonal antibodies Neutralizing antibodies provide repurposing researcher SARS-COV-2 infection SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody sequence sequences severe SARS severe SARS-CoV-2 shown therapeutic Treatment treatment of COVID-19 Tremelimumab Vaccine Viral viral neutralization widespread [DOI] 10.1038/s41598-021-89621-6 PMC 바로가기 [Article Type] Article
Genome-Wide Variation in BetacoronavirusesGenetic Diversity and Evolution Published on 2021-05-122022-10-30 Journal: Journal of Virology [Category] COVID-19, [키워드] acute respiratory syndrome Analysis antibody Antiviral antiviral drugs bat Betacoronavirus biological property Combination contributing to coronavirus COVID-19 Critical Defense diagnostic test diagnostic tests disorder Evolution form Genetic Genome genomic variation genus Betacoronavirus glycoprotein S highlight homologous Host host adaptation humans implication include infect Infection infection with SARS-CoV-2 manifested MERS-CoV Middle East Mutation natural new strain ORF1b ORF8 Other pathogenicity Probability profile property Protein protein S provide reliability repeated Replication respiratory syndrome coronavirus S glycoprotein S protein SARS-CoV SARS-CoV-2 SARS-CoV-2 strain selection pressure strain Strains Trigger Vaccine Vaccine design Variation virus [DOI] 10.1128/JVI.00496-21 PMC 바로가기 [Article Type] Genetic Diversity and Evolution
A systematic review of the case findings, testing and management of COVID-19COVID-19의 사례 발견, 테스트 및 관리에 대한 체계적인 검토Article Published on 2021-05-122022-09-11 Journal: F1000Research [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alternative analyzed Antibody test antibody tests Antigen applied approaches article can be used case detection mechanism case finding Case management Chain Reaction Control coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 COVID-19 cases determine diagnostic diagnostic test diagnostic test. Direct Disease progression early diagnosis expected Health Organization highest inclusion criteria item management mass men meta-analyses outcome Patient PCR PICO polymerase chain polymerase chain reaction Population positive PRISMA ProQuest rapid antibody test Rapid test real-time polymerase chain reaction Reporting review risk RT-PCR SARS-CoV-2 Science Science Direct sensitivity Serological assay severe acute respiratory syndrome Coronavirus specificity Spread Symptom symptomatic Symptoms systematic review systematic reviews World Health Organization [DOI] 10.12688/f1000research.50929.3 PMC 바로가기 [Article Type] Article
Antibody (Serology) Tests for COVID-19: a Case StudyCOVID-19에 대한 항체(혈청) 검사: 사례 연구Opinion/Hypothesis Published on 2021-05-122022-09-12 Journal: mSphere [Category] SARS, 진단, [키워드] antibody Antibody test Antibody testing antibody tests approach asymptomatic infection asymptomatic infections case study COVID-19 COVID-19 pandemic detect develop diagnostic test diagnostic tests diagnostics employment FDA Guidance Health identify Immunity Immunity passports infections initial Interpretation limitation market Policy positive Regulatory SARS-CoV-2 SARS-COV-2 infection serology serology test serology tests social distancing Test [DOI] 10.1128/mSphere.00201-21 PMC 바로가기 [Article Type] Opinion/Hypothesis
The importance of ongoing international surveillance for Creutzfeldt–Jakob disease Reviews Published on 2021-05-102022-10-05 Journal: Nature reviews. Neurology [Category] 바이오마커, 변종, [키워드] bovine CNS Control Creutzfeldt–Jakob disease declined diagnostic test disease Diseases distribution Encephalopathy Evidence form high-sensitivity assay human population iatrogenic incidence International measure neurodegenerative pathophysiology Perspective Protein public health question raised Research review risk secondary transmission Support Surveillance theoretical risk tissue Transmission variant [DOI] 10.1038/s41582-021-00488-7 [Article Type] Reviews
Review of Current COVID-19 Diagnostics and Opportunities for Further DevelopmentMedicine Published on 2021-05-072022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] in-vitro assay access Accuracy alternative antibody assay Antigen antigen test assays Asymptomatic caused clinical clinical utility confirmation Contact Contact tracing Contamination coronavirus 2 coronavirus disease COVID-19 Critical current decrease development diagnostic diagnostic test diagnostic testing diagnostics equipment Evolution facilitate false-negative False-positive imperative indications infected individuals Infection limitations molecular test MONITOR NAAT nucleic acid amplification occur opportunity pandemic performed Point polymerase chain public health Rapid respiratory respiratory specimens review RNA RT-PCR RT-PCR assay SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 testing Sequencing serologic test Strategy suggested symptomatic the SARS-CoV-2 genome while [DOI] 10.3389/fmed.2021.615099 PMC 바로가기 [Article Type] Medicine
Seroprevalence of SARS-CoV-2 IgG antibodies and risk factors in health care workers at an academic medical center in Boston, Massachusetts매사추세츠주 보스턴에 있는 학술 의료 센터에서 의료 종사자의 SARS-CoV-2 IgG 항체 및 위험 인자의 혈청 유병률Observational Study Published on 2021-05-062022-09-01 Journal: Scientific Reports [Category] SARS, 임상, 진단, [키워드] Abbott Abbott SARS-CoV-2 IgG acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Boston cause center collected coronavirus coronavirus disease COVID-19 COVID-19 symptom COVID-19 symptoms demographics diagnostic diagnostic test distance Epidemiology Gender HCW HCWs Health care Health care worker health care workers healthcare worker Healthcare workers help highlight hygiene IgG antibody increased risk Infection prevention infection rates lack majority Massachusett Measures Mild mitigate observational study participant Personal protective equipment physical distancing positive PPE Prevention and control promote questionnaire respiratory risk factor Sample SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibody seronegative seropositive Seropositivity Seroprevalence serum sample serum samples severe acute respiratory syndrome Coronavirus tested virus [DOI] 10.1038/s41598-021-89107-5 PMC 바로가기 [Article Type] Observational Study
Low saliva pH can yield false positives results in simple RT-LAMP-based SARS-CoV-2 diagnostic tests낮은 타액 pH는 간단한 RT-LAMP 기반 SARS-CoV-2 진단 테스트에서 위양성 결과를 산출할 수 있습니다.Research Article Published on 2021-05-052022-09-10 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, [키워드] amplification can be used causative agent COVID-19 COVID-19 infection Diagnostic method diagnostic test dissemination False positive fluctuation hospital Hospital environment Infectious disease isothermal lack Modification nasopharyngeal sample Nasopharyngeal swab nasopharyngeal swabs nucleic acids Prevent reliability RNA extraction RNA purification RT-LAMP RT-qPCR RT-qPCR test Saliva salivary SARS-CoV-2 SARS-CoV-2 detection sensitivity Treatment Viral viral nucleic acids VTM [DOI] 10.1371/journal.pone.0250202 PMC 바로가기 [Article Type] Research Article
A Case of Postural Orthostatic Tachycardia Syndrome Secondary to the Messenger RNA COVID-19 VaccineInternal Medicine Published on 2021-05-042022-10-31 Journal: Cureus [Category] COVID-19, [키워드] activate acute respiratory syndrome antibody autoimmune basis autoimmune pots Autoimmune reaction autonomic Case report clinically conducted connection coronavirus coronavirus disease COVID 19 COVID-19 COVID-19 vaccine diagnosed Diagnosis diagnostic test disease Dizziness Dysautonomia dysfunction fatigue first dose Headaches help immune system implication include male mechanism messenger Messenger RNA Modification mRNA mRNA vaccine mRNA-based vaccine nervous system Numerous onset of symptom orthostatic pathophysiology Patient Prevalence Research RNA secondary to Side effect Symptom syndrome Tachycardia Trigger triggered unique Vaccine Vaccines viruses [DOI] 10.7759/cureus.14837 PMC 바로가기 [Article Type] Internal Medicine