Vaccine Development against COVID-19: Study from Pre-Clinical Phases to Clinical Trials and Global UseReview Published on 2021-07-292022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] analyzed approval candidate vaccine clinical clinical investigation clinical trials COVID-19 development dissemination distribution dose Efficacy effort General population global demand highest immunize individual International investigated National pharmaceutical companies phase phase 3 trial PROTECT Regulatory required risk Stage subsequent vaccination Vaccine vaccine candidate Vaccines WHO World Health Organization [DOI] 10.3390/vaccines9080836 PMC 바로가기 [Article Type] Review
Preprints in times of COVID19: the time is ripe for agreeing on terminology and good practicesDebate Published on 2021-07-282022-10-28 Journal: BMC Medical Ethics [Category] Coronavirus, Fulltext, SARS, [키워드] Community complexity Consensus Consequences COVID19 dissemination FIVE help include increase increasingly information International manuscript media non-peer reviewed over peer peer-reviewed raise Research research finding research findings submitted terminology thought [DOI] 10.1186/s12910-021-00667-7 PMC 바로가기 [Article Type] Debate
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitroArticle Published on 2021-07-282022-10-04 Journal: Nature Communications [Category] SARS, 변종, [키워드] anti-viral activity antibody binding block Brain cells cofactor Coronaviruses dissemination Effect expression Gut human cell human lung human lung cells IFITM in vitro in vitro model in vivo Infection inhibit inhibit SARS-CoV-2 Innate immunity interact interferon organoids overexpression Pathogenesis peptide promote Protein Replication reported representing restrict SARS-CoV-2 SARS-COV-2 infection spike Support target the SARS-CoV-2 therapeutic approaches transmembrane protein viral infection viral pathogens Viral transmission virus entry virus inhibition viruses were expressed [DOI] 10.1038/s41467-021-24817-y PMC 바로가기 [Article Type] Article
COVID-19 Associated Rhino-Orbital Mucormycosis Complicated by Gangrenous and Bone Necrosis—A Case Report from HondurasCase Report Published on 2021-07-272022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] addition affecting bone Coinfection complications COVID-19 COVID-19 diagnosis COVID-19 pandemic described Dexamethasone diabetes Diagnosis dissemination fatality Fungal infection histopathological honduras Immunocompromised patients increase in infections invasive life-threatening male many cases Mucorale Mucorales Mucormycosis Necrosis Occurrence opportunistic outcomes Patient report reported Risk factors SARS-CoV-2 survived tissue Treatment use of steroids [DOI] 10.3390/vaccines9080826 PMC 바로가기 [Article Type] Case Report
The Effect of a Wordless, Animated, Social Media Video Intervention on COVID-19 Prevention: Online Randomized Controlled TrialRandomized Controlled Trial Published on 2021-07-272022-10-04 Journal: JMIR Public Health and Surveillance [Category] 임상, [키워드] 95% CI APC approach baseline level baseline levels clinical Controlled COVID-19 cultural and social implications detect Digital health dissemination Effect effective Effectiveness enrolled examined experiments feature FIVE Germany global health Health Health authority highlight Identifier infodemiology information literacy International Intervention knowledge List experiment media objective pandemic participant pathway Placebo primary endpoint public health question Randomized Randomized controlled trial Registration report Result significantly higher social media Spain statistically significant The United States trial participant United Kingdom video intervention [DOI] 10.2196/29060 PMC 바로가기 [Article Type] Randomized Controlled Trial
A Global Overview of COVID-19 Research in the Pediatric Field: Bibliometric ReviewReview Published on 2021-07-232022-10-29 Journal: JMIR Pediatrics and Parenting [Category] COVID-19, [키워드] Analysis applied article articles authors average bibliometric review children China Clinical characteristics Clinical features Cluster country COVID-19 COVID-19 pandemic database dissemination evaluate geographical areas globe impacted Italy Lancet literature mental health methodology objective Pathogenesis pediatric pediatrics psychological Impact public health publications Research Result retrieved review SARS-CoV-2 searched Spread the disease The United States therapeutic Topic with COVID-19 [DOI] 10.2196/24791 PMC 바로가기 [Article Type] Review
Optimization and Standardization of Human Saliva Collection for MALDI-TOF MSArticle Published on 2021-07-212022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Analysis approach Biomarker buffer Collection Combination Diagnosis dissemination experiment healthcare healthy Human Immunity individual intervals intra-individual Isolation key factor limit machine learning approaches MS profiling MS spectra Non-invasive occur optimization outbreak performed positive profile protein precipitation reproducibility Research Saliva saliva specimen SARS-CoV-2 SARS-CoV-2 diagnosis SARS-COV-2 infection stability Standardization storage condition vaccination virus [DOI] 10.3390/diagnostics11081304 PMC 바로가기 [Article Type] Article
Protocol for DexEnceph: a randomised controlled trial of dexamethasone therapy in adults with herpes simplex virus encephalitisDexenceph의 프로토콜 : 단순 포진 바이러스 뇌염을 가진 성인의 덱사메타손 요법의 무작위 대조 시험Neurology Published on 2021-07-212022-09-10 Journal: BMJ Open [Category] Fulltext, SARS, 임상, 치료기술, 치료제, [키워드] 1:1 aciclovir Antiviral treatment approval ARMS Brain cerebrospinal fluid Clinical outcome clinical outcomes completion Consequences control arm Corticosteroid corticosteroid therapy determine Dexamethasone disease dissemination DNA Encephalitis Ethical approval Ethics ethics committee EudraCT Evidence facilitate functional herpes simplex herpes simplex virus Immunosuppression IMPROVE include index Inflammation memory multicentre neurological injury NEUROLOGY occur Open-label outcome outcomes Patient Pragmatic Primary outcome problem randomisation randomised randomised controlled trial rare disease receive recruited recruitment reducing registration numbers Research Ethics scale secondary Secondary outcomes standard treatment standard treatment alone survivor target temporal lobe therapy Trial verbal Viral viral replication Virology virus virus encephalitis worsening [DOI] 10.1136/bmjopen-2020-041808 PMC 바로가기 [Article Type] Neurology
Smart City and Crisis Management: Lessons for the COVID-19 PandemicReview Published on 2021-07-212022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] adverse effect Analysis catastrophic city Community community well-being COVID-19 COVID-19 pandemic crisis crisis management Critical Digital literacy dissemination Effect ENhance exclusion functional functions inefficient lesson literature review maintain management media mental health mitigate monitoring systems MOST physical Planning recommendation Research Resilience Side effects SmaRT smart city suggested technology urban resilience [DOI] 10.3390/ijerph18157736 PMC 바로가기 [Article Type] Review
Viral Load and Patterns of SARS-CoV-2 Dissemination to the Lungs, Mediastinal Lymph Nodes, and Spleen of Patients with COVID-19 Associated Lymphopenia폐, 종격동 림프절 및 COVID-19 관련 림프 감소증 환자의 비장에 대한 SARS-COV-2 보급의 바이러스 부하 및 패턴Article Published on 2021-07-202022-09-10 Journal: Viruses [Category] SARS, 진단, 치료기술, [키워드] ABL1 Alveolar macrophages bronchiolar epithelial cell bronchiolar epithelial cells bronchopneumonia Cell change Course COVID-19 cytoplasm DAD died dissemination Endothelial cell epithelial cells Genetic hematological Infection load lung lung tissue lung tissues Lungs lymph lymph nodes lymphocyte Lymphocytes lymphopenia macrophages median molecular multiplex real-time polymerase chain reaction Pathogenesis Patient patients pattern Pneumocytes proliferative SARS-CoV-2 SARS-CoV-2 cDNA SARS-CoV-2 particle SARS-CoV-2 particles SARS-CoV-2 protein SARS-CoV-2 proteins spleen transmission electron microscopy Viral Viral load with COVID-19 [DOI] 10.3390/v13071410 PMC 바로가기 [Article Type] Article