COVID-19 and coinfection with Clostridioides ( Clostridium ) difficile in an infant with gastrointestinal manifestationCase Report Published on 2020-11-252022-10-31 Journal: Einstein [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Admission Clostridioide Clostridioides difficile infection Clostridium Coagulation Coinfecção Coinfection complementary complications coronavirus Coronavirus infections COVID-19 diagnosed diarrhea discharged Evidence exacerbate facilitated Fever gastrointestinal tract Infant Infecções por coronavírus infecção Infection intensive care intravenous Lactente Mild moderate nasopharyngeal Patient pediatric persistence rhinorrhea SARS-CoV-2 Symptom Symptoms the patient transmission of SARS-CoV-2 Trato gastrointestinal vomiting [DOI] 10.31744/einstein_journal/2020RC6048 PMC 바로가기 [Article Type] Case Report
Convenience and comfort: reasons reported for using drugs alone among clients of harm reduction sites in British Columbia, CanadaResearch Published on 2020-11-232022-10-31 Journal: Harm Reduction Journal [Category] COVID-19, [키워드] 95% CI adjusted odds ratio age alcohol Analysis Canada changes Community convenience coronavirus disease death rate Descriptive statistics distribution drug eliminating exacerbate Factor Gender highest impacted individual Intervention measure mitigate MOST multivariable logistic regression North not differ occurred opioid overdose overdose crisis Prevalence recruited reduction reported response Result risk Using alone Using drugs alone were used [DOI] 10.1186/s12954-020-00436-6 PMC 바로가기 [Article Type] Research
The Pivotal Role of Adipocyte-Na K peptide in Reversing Systemic Inflammation in Obesity and COVID-19 in the Development of Heart FailureReview Published on 2020-11-142022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] ACE-2 ACE-2 receptor Activation acute respiratory syndrome adipocyte adipocytes administration adverse outcome amplification amplify antioxidant Cell complex Concentration coronavirus coronavirus disease COVID COVID-19 Cytokine storm Cytokines Cytokines storm death degrade demonstrated development drug enzyme exacerbate Express expression failure fat form global pandemic group heart heart failure heme oxygenase increase infected with COVID-19 Infection Inflammatory cytokine Inflammatory mediators Laboratory Modification Na/K-ATPase obese obese patients obesity pandemic Patient peptide Proteins reactive oxygen species reactive oxygen specy receptor reduction regulate renal responsible risk RNA role ROS ROS production SARS-CoV-2 selective shown Signaling subjects subunit susceptibility systemic systemic cytokine systemic inflammation tissue virus white with COVID-19 [DOI] 10.3390/antiox9111129 PMC 바로가기 [Article Type] Review
Will prenatal exposure to SARS-CoV-2 define a birth cohort with accelerated aging in the century ahead?Rapid Communication Published on 2020-11-102022-10-31 Journal: Journal of Developmental Origins of Health and Disease [Category] COVID-19, MERS, SARS, 신종인플루엔자, [키워드] 1918 epidemic accelerated acute respiratory syndrome adverse impact Affect age Cognitive function Cohort cohort study consequence COVID-19 COVID-19 disease COVID-19 pandemic Depression develop developmental diabetes disease Effect Effects element exacerbate exaggerated inflammatory response exposure in utero fetal Health Impact in utero Infection infection with COVID-19 initiated ischemic heart disease marker Mortality Neonatal observation pandemic physical placental postnatal development Pregnancy prenatal Research SARS-CoV-2 Stress Thromboembolic events Vascular virus [DOI] 10.1017/S204017442000104X PMC 바로가기 [Article Type] Rapid Communication
Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly populationReview Published on 2020-11-062022-10-29 Journal: Seminars in immunopathology [Category] COVID-19, MERS, SARS, [키워드] age boost candidate clinical study clinical testing Comorbidities complex COVID-19 cytokine effective Effectiveness effort exacerbate Factor fraction help identify immune responses immune responsiveness immunopathological immunosenescence inflammaging lack marker mechanism Older older population overlap pharmacological treatments phenotype Prognosis recent response risk robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2 vaccine Systems biology tested vaccination vaccination efficacy Vaccination strategy Vaccine Vaccine development vaccine response virulence [DOI] 10.1007/s00281-020-00821-0 PMC 바로가기 [Article Type] Review
COVID-19 and Parkinson’s Disease: Shared Inflammatory Pathways Under Oxidative Stress †Article Published on 2020-10-312022-10-28 Journal: Brain Sciences [Category] COVID-19, [키워드] 6OHDA Activation acute respiratory syndrome affected alignment Apoptosis basic Bioinformatics analysis Brain caspase caused cell line Chronic disorder complications contribute coronavirus correlated COVID-19 death ENhance Evidence exacerbate Health human cell identify immortalized Increasing indicated individual Infection inflammatory pathway inhibitors knowledge laboratory data literature review Neuron NFκB nuclear factor kappa B (NFκB) oxidative stress pandemic Parkinson’s disease Parkinson’s disease pathway Patient progression proteome reduced resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 protein selective similarity specific inhibitor Therapeutic approach Toxicity Treatment triggered [DOI] 10.3390/brainsci10110807 PMC 바로가기 [Article Type] Article
Emerging Mechanisms of Pulmonary Vasoconstriction in SARS-CoV-2-Induced Acute Respiratory Distress Syndrome (ARDS) and Potential Therapeutic TargetsReview Published on 2020-10-292022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS, [키워드] 1918 influenza acute lung injury acute respiratory distress acute respiratory syndrome ARDS Atypical caused characterized clinically coronavirus coronavirus disease COVID-19 COVID-19 patient cytokine release storm described disease Endothelin exacerbate hallmark highlight hypoxic-adenosinergic response increase in International Kallikrein–Kinin System Lung injury mechanism Novel coronavirus outbreak pandemic Potential potential treatment option promote pulmonary pulmonary hypertension recent renin angiotensin system respiratory Respiratory illness respiratory viral infection SARS-CoV-2 SARS-COV-2 infection severe hypoxemia spread to syndrome target tested Vascular vascular dysfunction vasoconstriction [DOI] 10.3390/ijms21218081 PMC 바로가기 [Article Type] Review
The Public Health Impact of Coronavirus Disease on Human TraffickingPublic Health Published on 2020-10-292022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] activity acute respiratory syndrome amplify children Community Contact coronavirus coronavirus disease COVID-19 distress exacerbate global pandemic Health impact health systems Healthcare professional Human human trafficking Impact Isolation labor trafficking limitation offered organizations patients prevention professional Public public health resource resources risk risk factor sex trafficking Social service [DOI] 10.3389/fpubh.2020.561184 PMC 바로가기 [Article Type] Public Health
Cognitive and Neuropsychiatric Manifestations of COVID-19 and Effects on Elderly Individuals With DementiaNeuroscience Published on 2020-10-262022-10-31 Journal: Frontiers in Aging Neuroscience [Category] COVID-19, [키워드] acute respiratory syndrome Affect Alzheimer Anxiety assessments Atypical bilateral pneumonia Brain Care caused change chronic clinical trial Cognition cognitive Cognitive impairment cognitive impairments Comorbidity consequence contributed coronavirus coronavirus disease COVID-19 Dementia described discharge disease drugs dysfunction Effect elderly evaluated exacerbate Factor form generate Healthcare systems high risk hospital Hospitalization hypoxia impacted implementation increasingly individual Insomnia intensive care loneliness manifestation measure mechanical ventilation medication Mental mental health Mild symptom Mortality multifactorial neurologic Neuropsychiatric neuropsychiatry organs Pandemics Patient Post-traumatic stress disorder potential mechanism Prevalence proportion provided Psychiatric rates of infection rehabilitation reported Research Respiratory system SARS-CoV-2 social distancing Spread survivor Symptom systemic inflammation these symptom treat triggering virus worsening [DOI] 10.3389/fnagi.2020.588872 PMC 바로가기 [Article Type] Neuroscience
The Influence of the Lectin Pathway of Complement Activation on Infections of the Respiratory SystemImmunology Published on 2020-10-212022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Activation affecting association cause collectin complement Complement activation complexes concerning contribute COVID-19 disease exacerbate Factor ficolin Infection influence lectin lectin pathway mannose-binding lectin MASP MASP-2 MBL morbidity and mortality Neonatal Pneumonia Prevent respiratory respiratory infection respiratory infections Respiratory system serine protease Side effects System tissue damage Tuberculosis variety [DOI] 10.3389/fimmu.2020.585243 PMC 바로가기 [Article Type] Immunology