Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors Research Published on 2021-02-172022-10-05 Journal: Nature cancer [Category] 변종, 유전자 메커니즘, [키워드] Cancer cascade children clinical Clinical use Diagnosis DNA sequencing dominant downstream Genes genetics germline individual moderate pathogenic Patient pediatric positive result predisposition Prospective reported reproductive risk reduction solid tumor Therapies translation undergo variant [DOI] 10.1038/s43018-021-00172-1 [Article Type] Research
Nucleoside Analogs and Nucleoside Precursors as Drugs in the Fight against SARS-CoV-2 and Other CoronavirusesSARS-CoV-2 및 기타 코로나바이러스와의 싸움에서 약물로서의 뉴클레오사이드 유사체 및 뉴클레오사이드 전구체Review Published on 2021-02-132022-08-31 Journal: Molecules [Category] MERS, 신약개발, 치료제, [키워드] active against acute respiratory syndrome approach China colds common colds coronavirus coronavirus disease CoV COVID-19 CoVs derivative drug effective drug effective drugs effective therapy Epidemics family Coronaviridae Favipiravir focus growth HCoV Health Organization human CoV humans Infection infections inhibit lead main mechanism mammal mammals mass vaccination MERS MERS-CoV Middle East Middle East respiratory syndrome Mild molnupiravir nucleoside nucleoside drugs nucleosides Other pandemic positive result positive-sense precursor provide Remdesivir respiratory respiratory diseases respiratory infections responsible ribavirin RNA SARS-CoV-1 SARS-CoV-2 SARS-COV-2 infection Severe acute respiratory syndrome severe respiratory disease severe respiratory diseases sofosbuvir Spread the SARS-CoV-2 therapy upper respiratory infection vaccination Viral diseases virus viruses while WHO World Health Organization [DOI] 10.3390/molecules26040986 PMC 바로가기 [Article Type] Review
Comparison of Severe Acute Respiratory Syndrome Coronavirus 2 Screening Using Reverse Transcriptase–Quantitative Polymerase Chain Reaction or CRISPR-Based Assays in Asymptomatic College Students무증상 대학생에서 역전사효소-정량적 중합효소 연쇄 반응 또는 CRISPR 기반 분석을 사용한 중증 급성 호흡기 증후군 코로나바이러스 2 선별 검사의 비교Comparative Study Published on 2021-02-112022-09-10 Journal: JAMA Network Open [Category] MERS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age approach assays Asymptomatic Asymptomatic case capture chain Chain Reaction clinical clinical laboratory clinical samples Cohort cohort study collected college Community Concordance Containment coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 covert COVID-19 CREST CRISPR determine diagnostic diagnostic testing effective evaluated exposure female finding highlighting Importance improvement in viral individual information Laboratory leading edge Local lockdown measure Measures Metrics Mitigation objective offer oropharyngeal swab outbreak Outbreaks pandemic participant Point polymerase chain polymerase chain reaction positive positive result positive sample Prevalence public health qPCR reaction Relaxation Relevance reopening required respiratory Result reverse transcriptase rising RT-qPCR SARS-CoV-2 SARS-CoV-2 testing screened Screening setting severe acute respiratory syndrome Coronavirus shift student study participant Study participants surveillance testing test results Testing universities Viral Viral load viral loads Viral transmission virus virus detection [DOI] 10.1001/jamanetworkopen.2020.37129 PMC 바로가기 [Article Type] Comparative Study
Clinical presentation and outcomes of the first patients with COVID-19 in Argentina: Results of 207079 cases from a national databaseResearch Article Published on 2021-02-112022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] Admission adverse outcome age Analysis Asthma Care case report form clinical Clinical characteristics Clinical diagnosis Clinical sign co-morbidity Coma condition conducted Contact cough country COVID-19 database dataset defined diabete diagnosed disease severity Dyspnea Effects elevated Evidence Factor Fatality rate Fever Follow-up headache healthcare Healthcare provider hypertension ICU admission immunodeficiency information initial intensive care Latin Latin America Liver disease male Male sex males measure Mild morbidities MOST nasal National obesity Older age outcome pandemic patients with COVID-19 Pharyngeal swab polymerase chain positive positive result question renal Result risk factor RT-PCR RT-PCR testing SARS-COV-2 infection Seizures Sequencing sore throat specimens Symptom Symptoms System tachypnea was collected [DOI] 10.1371/journal.pone.0246793 PMC 바로가기 [Article Type] Research Article
Characterization of SARS-CoV-2 RNA, Antibodies, and Neutralizing Capacity in Milk Produced by Women with COVID-19COVID-19에 걸린 여성이 생산한 우유의 SARS-CoV-2 RNA, 항체 및 중화 능력의 특성화Research Article Published on 2021-02-092022-09-10 Journal: mBio [Category] MERS, 진단, 치료기술, [키워드] addition analyzed anti-SARS-CoV-2 antibodies benefit Breastfeeding breastmilk Capacity characterization Child collected COVID-19 COVID-19 diagnosis COVID-19 illness COVID-19 pandemic cross-sectional detect Evidence evidence of human milk IgA IgG in vitro Infant Mild-to-moderate milk MOST mother neutralize neutralizing capacity occur Participants positive result previous study produced recommendation Result risk RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 transmission SARS-CoV-2-specific IgG suggested Support swabs Transmission transmission of SARS-CoV-2 Viral Viral RNA virus was collected with COVID-19 women [DOI] 10.1128/mBio.03192-20 PMC 바로가기 [Article Type] Research Article
Dynamic Panel Data Modeling and Surveillance of COVID-19 in Metropolitan Areas in the United States: Longitudinal Trend AnalysisOriginal Paper Published on 2021-02-092022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, [키워드] activity Analysis approach Area Arellano-Bond estimator Atlanta average Baltimore Boston calculated Charlotte Chicago COVID-19 COVID-19 7-day lag COVID-19 cities COVID-19 metropolitan areas COVID-19 pandemic COVID-19 transmission COVID-19 transmission deceleration COVID-19 transmission jerk Dallas Denver Detroit dynamic dynamic panel data Effect effective Effects extreme First wave generalized method of moments generalized method of the moments global COVID-19 surveillance GMM Health highest Houston Impact increase in Local lockdowns longitudinal Los Angeles measure Metrics Miami Minneapolis modeling New York City objective Orlando pandemic Panel persistence Philadelphia Phoenix Portland positive result public health Regulation Result risk Riverside San Antonio San Diego San Francisco SARS-CoV-2 SARS-CoV-2 surveillance Seattle second wave spike St Louis statistically Study design Surveillance Tampa the United State The United States Transmission trend turn US COVID-19 US COVID-19 surveillance system US COVID-19 transmission acceleration US COVID-19 transmission speed US econometrics US public health surveillance US SARS-CoV-2 US surveillance metrics Vaccine variable virus Washington, DC wave 2 wave two [DOI] 10.2196/26081 PMC 바로가기 [Article Type] Original Paper
Repeated Antigen-Based Rapid Diagnostic Testing for Estimating the Coronavirus Disease 2019 Prevalence from the Perspective of the Workers’ Vulnerability before and during the Lockdown폐쇄 전과 폐쇄 중 근로자 취약성의 관점에서 코로나바이러스 질병 2019 유병률 추정을 위한 항원 기반 신속 진단 반복 테스트Article Published on 2021-02-092022-09-12 Journal: International Journal of Environmental Research an [Category] MERS, 진단, [키워드] angle Antigen antigen rapid test Asymptomatic category chain Chain Reaction change changes in community transmission Consent coronavirus COVID-19 diagnosed employment evaluate Greece highlight independent infection control information investigated job likelihood lockdown lockdown restrictions measure no significant differences participant Patient polymerase chain reaction positive positive result Prevalence previous study proportion Rapid Rapid test reaction Real-time reverse transcriptase polymerase chain reaction respiratory respiratory symptom respiratory symptoms reverse transcriptase SARS-CoV-2 Screening significant difference Sociodemographic Test Testing the SARS-CoV-2 vulnerability was used were recorded [DOI] 10.3390/ijerph18041638 PMC 바로가기 [Article Type] Article
Experience of clinical screening for COVID-19 among patients undergoing elective orthopedic surgeries: an alternative proposalObservational Study Published on 2021-02-022022-10-04 Journal: Journal of Orthopaedic Surgery and Research [Category] MERS, 임상, [키워드] acute respiratory syndrome affected age average cohort of patient Contact coronavirus coronavirus disease COVID-19 COVID-19 pandemic death diagnostic tests early stage epidemiological Evidence experience female Hospitalized implementation incidence of COVID-19 involved Isolation Level molecular Mortality multicenter orthopedic Orthopedic procedures Outpatient surgical procedures pandemic Patient patients died performed physical Physical examination positive result postoperative protocol recorded Result retrospective RT-PCR test SARS-CoV-2 serological Support Surgical Procedure Symptom Symptoms symptoms of COVID-19 tested the disease with COVID-19 [DOI] 10.1186/s13018-021-02217-8 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2 diagnostics in the virology laboratory of a University Hospital in Rome during the lockdown period폐쇄 기간 동안 로마에 있는 대학 병원의 바이러스 연구소에서 SARS-CoV-2 진단Article Published on 2021-02-012022-09-11 Journal: Journal of medical virology [Category] Fulltext, MERS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 affected age Analysis analyzed Bronchoalveolar lavage cerebrospinal cerebrospinal fluid China confirmed case continuous surveillance coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 diagnostics Epidemiology Evolution fluids gargle highlighting individuals Infection infections information Italian regions Italy Laboratory laboratory diagnostics. lockdown male nasopharyngeal swabs pandemic Patient pleural fluids positive result reached respiratory Respiratory samples Rome SARS-CoV-2 SARS-CoV-2 epidemiology Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Sex single-center specimen spread to Stool stools subject Surveillance tested university Variation Virology virus [DOI] 10.1002/jmv.26332 PMC 바로가기 [Article Type] Article
Tracing surface and airborne SARS-CoV-2 RNA inside public buses and subway trains공공 버스 및 지하철 내부 표면 및 공기 중 SARS-CoV-2 RNA 추적Article Published on 2021-02-012022-09-11 Journal: Environment international [Category] SARS, 치료기술, 치료제, [키워드] air conditioning ambient analysed applied Barcelona best circulation complement Concentration COVID-19 COVID-19 case COVID-19 cases Disinfection effective Efficiency eliminating Elimination evaluate evaluated Evidence examined gene target greatly reduce hygiene indicate Infection information lack MOST nocturnal Ozone pandemic peaking personal hygiene positive positive result Probability provided Public public transport Region remained resulting risk RNA RNA gene RT-PCR RT-PCR analysis RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 virus selected subway Support Swab swabs targets the SARS-CoV-2 virus tracing Transport unlikely vehicle Ventilation Viral Viral RNA viral RNA fragment viral RNA fragments Viral transmission virus widespread yielding [DOI] 10.1016/j.envint.2020.106326 PMC 바로가기 [Article Type] Article