Robust Neutralizing Antibody Responses 6 Months Post Vaccination with BNT162b2: A Prospective Study in 308 Healthy IndividualsCommunication Published on 2021-10-122022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] age Analysis anti-SARS-CoV-2 humoral BNT162b2 BNT162b2 mRNA vaccine booster Booster vaccine COVID-19 COVID-19 vaccination declining dose eight eliminated examined healthy individual Humoral immunity Immunity in healthy individuals individual less malignant disease Month Neutralizing antibodies neutralizing antibody Older participant post vaccination Prospective public health response SARS-CoV-2 second vaccination subject timepoints vaccination Vaccine were measured [DOI] 10.3390/life11101077 PMC 바로가기 [Article Type] Communication
A prospective, randomized, single-blinded, crossover trial to investigate the effect of a wearable device in addition to a daily symptom diary for the Remote Early Detection of SARS-CoV-2 infections (COVID-RED): a structured summary of a study protocol for a randomized controlled trialSARS-COV-2 감염 (COVID-RED)의 원격 조기 발견을위한 일일 증상 일기 외에 웨어러블 장치의 효과를 조사하기위한 전향 적, 무작위, 단일 맹장, 크로스 오버 시험 : 연구의 구조적 요약.무작위 제어 시험을위한 프로토콜Update Published on 2021-10-112022-09-01 Journal: Trials [Category] MERS, SARS, 임상, 진단, 치료기술, 치료제, [키워드] 1:1 addition adhere Algorithm Algorithms all subject all subjects among others analysed antibody Antibody testing antibody tests Antigen antigen tests approach asked assigned Asymptomatic asymptomatic individual asymptomatic infection average baseline blinded Blinding can not capillary blood Chain Reaction changes in Characteristics cholinergic urticaria Cohort collected Complete conditions conducted consent form contribute control condition COVID-19 COVID-19 infection COVID-19 vaccination current Daily defined demographics described detect detection determine develop deviation diary dissemination Early detection element eligibility criteria eligible End enrolled enrolment evaluate exclusion exploratory feedback Follow-up followed by gold gold standard Health health resource heart rate incidence rates Inclusion inclusion criteria individual individuals infected individual infected individuals infected with SARS-CoV-2 Infection information Informed consent informed consent form initial involved Laboratory laboratory-confirmed SARS-CoV-2 infection machine learning management maximum media medical history Mobile application must nasal swab National natural infection Negative predictive value Netherland Netherlands notification NPV number objective occur outcome pacemaker parameter participant PCR PCR test PCR tests physiological physiological parameters polymerase chain polymerase chain reaction populations portal positive Positive predictive value PPV pre-symptomatic Predictive value primary analysis profession proportion Prospective protocol provided public health Pulse rate questionnaire randomization randomization sequence Randomized Randomized controlled trial Randomly receive recommendation recruited recruitment reduce remote reported resident resource responsible resulting risk RIVM Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 test SARS-CoV-2 virus sensitivity sequence sequence 1 Sequence 2 sequences serology serology test serology tests significantly skin temperature Smartphone social media specificity staff stratified stratified block randomization study participation Study protocol subject suffering supplementary material Symptom Symptom diary Symptoms target temperature test result tested the SARS-CoV-2 thought Transmission transmissions Trial Trial registration undergo urticaria used to evaluate vaccinated against COVID-19 vaccination Vaccine Variability wearable device website Well-being [DOI] 10.1186/s13063-021-05643-5 PMC 바로가기 [Article Type] Update
Prevalence of SARS-CoV-2 Infection in Children by Antibody Detection in Saliva: Protocol for a Prospective Longitudinal Study (Coro-Buddy)Protocol Published on 2021-10-082022-10-29 Journal: JMIR Research Protocols [Category] COVID-19, [키워드] antibody approach Asymptomatic Blood children Cohort collected Comparator group COVID-19 COVID-19 pandemic Data analysis detection determine disease enrolled Enrollment enzyme-linked immunosorbent epidemiological data Epidemiology Germany Identifier incidence Infants Infection lack longitudinal Mild symptom objective participant polymerase chain Prevalence Prospective recruited recruitment Registration report Result Saliva SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection School Schools Tübingen unique [DOI] 10.2196/27739 PMC 바로가기 [Article Type] Protocol
All-cause and cause-specific mortality in people with mental disorders and intellectual disabilities, before and during the COVID-19 pandemic: cohort studyResearch Paper Published on 2021-10-072022-10-30 Journal: The Lancet Regional Health - Europe [Category] COVID-19, [키워드] affective age average cause cause-specific mortality Cohort cohort study condition COVID-19 COVID-19 mortality death deaths Dementia developmental developmental disorders disorder disorders elevated Ethnic groups exacerbating foundation General population greater GSK healthcare Increased janssen London Mental Mental disorder Mortality NIHR nine pandemic Prospective Psychiatric psychiatric condition public health emergency remained risk risk of death SMR SMRs substance use disorders Takeda WHO with COVID-19 World Health Organization [DOI] 10.1016/j.lanepe.2021.100228 PMC 바로가기 [Article Type] Research Paper
Challenges in Steroid and Anticoagulant Therapy in Severe COVID-19 Pneumonia: A Prospective StudyArticle Published on 2021-10-062022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] acute kidney adopted Anti-inflammatory Anticoagulant assessment Assiut University Hospital bleeding C reactive protein challenge Clinical outcome comorbid diseases Complication conducted Corticosteroid Corticosteroids COVID-19 COVID-19 patient D-dimer discharge disease enoxaparin ferritin flexible Follow-up group hematoma highest hospital Hospital stay ICU In-hospital lowest Lung fibrosis Methylprednisolone mortality rate multivariable Myocardial infarction outcome Oxygen therapy Patient patient group patients predictor Prospective protocol RT-PCR severe COVID-19 patient Severe COVID-19 pneumonia severe pneumonia significant difference standard treatment steroid Study design therapeutic therapy three group Treatment Treatment protocol two groups was performed [DOI] 10.3390/antibiotics10101214 PMC 바로가기 [Article Type] Article
Investigating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Surface and Air Contamination in an Acute Healthcare Setting During the Peak of the Coronavirus Disease 2019 (COVID-19) Pandemic in London런던의 코로나바이러스 질병 2019(COVID-19) 대유행의 정점 동안 급성 의료 환경에서 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 표면 및 공기 오염 조사Observational Study Published on 2021-10-052022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 임상, 치료기술, [키워드] 95% confidence interval absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 air contamination Chain Reaction collected Contamination coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients cross-sectional cultured virus effective evaluated healthcare hospital hygiene indicated limit of detection London multisite observational study Odds ratio pandemic patients with COVID-19 PCR PCR cycle peak Personal protective equipment physical distancing polymerase chain polymerase chain reaction potential risk Prospective Prospective, cross-sectional, observational study Quantitative respiratory RNA SARS-CoV-2 setting severe acute respiratory syndrome Coronavirus surface surface contamination swabbing threshold value Transmission viral culture Viral RNA virus was determined χ2 test [DOI] 10.1093/cid/ciaa905 PMC 바로가기 [Article Type] Observational Study
A Prospective Cohort Study in Nonhospitalized Household Contacts With Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Symptom Profiles and Symptom Change Over Time중증 급성 호흡기 증후군 코로나바이러스 2 감염이 있는 입원하지 않은 가구 접촉에 대한 전향적 코호트 연구: 시간 경과에 따른 증상 프로필 및 증상 변화Article Published on 2021-10-052022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Asymptomatic asymptomatic infection asymptomatic infections Chain Reaction change characterized collected Community community. Contact Contact tracing contribute coronavirus coronavirus 2 COVID-19 COVID-19 symptoms described detectable disease enrolled Fever first positive household household contact household contacts Improved individual infection control laboratory-confirmed SARS-CoV-2 infection less median age Mild mild or asymptomatic infections mild symptoms nasopharyngeal specimen neurologic over PCR test polymerase chain polymerase chain reaction profile progression Prospective Public health interventions Recognition reported reported symptom resolved respiratory respiratory symptom respiratory symptoms rRT-PCR rRT-PCR test SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus Symptom Symptoms tested time upper respiratory Utah Viral transmission [DOI] 10.1093/cid/ciaa1072 PMC 바로가기 [Article Type] Article
Beyond Vaccines: Clinical Status of Prospective COVID-19 Therapeutics백신을 넘어: COVID-19 예상 치료제의 임상 상태Review Published on 2021-10-012022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 변종, 신약개발, 진단, 치료제, [키워드] accelerate addition Antiviral antivirals approach approaches approval approved drug Biology biology of SARS-CoV-2 candidate Candidates caused clinical Clinical course clinical status Clinical studies clinical study contribute country COVID-19 death demonstrated develop Dexamethasone distribution Efficiency Emergency Health Organization identify Immune escape immunization immunomodulators infected individual infected individuals Infection information interferons lab Long COVID long term Neutralizing antibodies New new infections nucleoside pandemic Patient polymerase problem Prospective protective effect reached Remdesivir reported Research SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 variant SARS-CoV-2 variants severe COVID-19 status Symptom the SARS-CoV-2 the vaccine the vaccines therapeutic Therapeutic benefit therapeutic benefits Therapeutic treatment Therapeutics today translation Treatment Treatment strategies treatment strategy vaccination rates Vaccine Viral World Health Organization world population [DOI] 10.3389/fimmu.2021.752227 PMC 바로가기 [Article Type] Review
National population prevalence of antibodies to SARS-CoV-2 among pregnant women in Scotland during the second wave of the COVID-19 pandemic: a prospective national serosurveyCOVID-19 전염병의 두 번째 물결 동안 스코틀랜드의 임산부 사이에서 SARS-CoV-2에 대한 항체의 전국 인구 유병률: 전향적 국가 혈청 조사Article Published on 2021-10-012022-09-12 Journal: Public health [Category] MERS, SARS, 진단, [키워드] 95% CI 95% confidence interval adjusted all age groups Antenatal antibodies antibody biochemical coronavirus COVID-19 COVID-19 pandemic determine elevated estimate fetal Increasing Infection majority Monday mother National organization population prevalence populations Pregnancy pregnant women progressed Prospective retrieved risk SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 seroprevalence Scottish second wave Sensitivity and specificity serology Seroprevalence Serosurvey significantly increased Stage susceptible tested trisomy Week women [DOI] 10.1016/j.puhe.2021.08.005 PMC 바로가기 [Article Type] Article
Post-COVID-19 symptoms 6 months after acute infection among hospitalized and non-hospitalized patients입원환자와 비입원환자의 급성 감염 후 6개월 후 증상Article Published on 2021-10-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI acute infection acute respiratory syndrome age anti-SARS-CoV-2 IgG bidirectional chronic Chronic COVID coronavirus coronavirus 2 COVID COVID survivors COVID-10 COVID-19 disease disease onset Early detection evaluated Factor female female gender Follow-up Gender Hospitalized ICU admission identify IgG antibodies IgG antibody increase in independent risk factor independent risk factors individual Inpatient interview investigated IQR Italy Long Long COVID median number of symptom Occurrence offered onset of symptoms Outpatient outpatients Patient patients Patients with post-COVID-19 syndrome post-COVID syndrome predictor Prevalence Prospective Prospective Study respiratory SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 IgG SARS-CoV-2 serology serological serology severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly significantly higher subgroup Symptom syndrome the disease the interview titre typical symptom typical symptoms with COVID-19 without symptom [DOI] 10.1016/j.cmi.2021.05.033 PMC 바로가기 [Article Type] Article