sera – Page 27 – Communicable Diseases Research

In Planta Production of the Receptor-Binding Domain From SARS-CoV-2 With Human Blood Group A Glycan Structures

Chemistry

Published on 2022-02-012022-10-31
Journal: Frontiers in Chemistry [Category] COVID-19,

Detection of SARS-CoV-2 variants by Abbott molecular, antigen, and serological tests

Abbott 분자, 항원 및 혈청 검사를 통한 SARS-CoV-2 변이체 검출

Article

Published on 2022-02-012022-09-11
Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, 치료제,

[키워드] (Alpha) (Beta) Abbott acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Alpha antibody assay Antibody assays Antigen Architect assays B.1.1.7 B.1.351 B.1.427 B.1.429 B.1.526 B.1.617.1 B.1.617.2 Beta Card circulating SARS-CoV-2 variants circulating variants clinical sample clinical samples competent conserved Coronavirus-2 COVID-19 Culture delta VoCs detect detection Device diagnostic diagnostic test diagnostic tests dilutions evaluate evaluated Genome IgG IgG and IgM IgM immune in silico Infection lateral flow log molecular Molecular assay molecular assays molecular diagnostics MONITOR P.1 P.2 PanBio Patient Rapid Rapid antigen tests Rapid test respiratory SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 variant sensitivity sequence sera serologic assay serologic assays serological test Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 silico predictions specimen symptom onset Test tested These data variant variant of concern variants of concern virus virus cultures VoC VOCs WA1
[DOI] 10.1016/j.jcv.2022.105080 PMC 바로가기 [Article Type] Article

Anti-spike antibodies and neutralising antibody activity in people living with HIV vaccinated with COVID-19 mRNA-1273 vaccine: a prospective single-centre cohort study

Research article

Published on 2022-02-012022-10-05
Journal: The Lancet Regional Health - Europe [Category] 유전자 메커니즘,

[키워드] addition administration age anti-S anti-S antibody Anti-spike antibody Antibody titre Antiretroviral therapy ART CD4+ T cell Cell Cohort cohort study collected Combination COVID-19 COVID-19 emergency detectable enrolled finding funding HIV HIV infection humoral immune response individual Italian male median Ministry of Health mRNA-1273 mRNA-1273 vaccine neutralising antibody activity not affected Outpatient performed plasma PLWHIV powerful tool Primary outcome produced prospective cohort robust SARS-CoV-2 SARS-CoV-2 pandemic sera stratified supported titre two-dose regimen vaccination vaccination schedule Viral load with COVID-19 with HIV
[DOI] 10.1016/j.lanepe.2021.100287 [Article Type] Research article

Robust induction of neutralizing antibodies against the SARS-CoV-2 Delta variant after homologous Spikevax or heterologous Vaxzevria-Spikevax vaccination

동종 Spikevax 또는 이종 Vaxzevria-Spikevax 백신 접종 후 SARS-CoV-2 Delta 변이체에 대한 중화 항체의 강력한 유도

Article

Published on 2022-02-012022-09-11
Journal: European Journal of Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

Isolation of SARS-CoV-2 B.1.1.28.2 (P2) variant and pathogenicity comparison with D614G variant in hamster model

햄스터 모델에서 SARS-CoV-2 B.1.1.28.2(P2) 변이체의 분리 및 D614G 변이체와의 병원성 비교

Article

Published on 2022-02-012022-09-11
Journal: Journal of infection and public health [Category] COVID19(2023년), SARS, 변종,

[키워드] acute respiratory syndrome B.1 B.1.1.28.2 body weight Body weight loss Brazil caused characterization Corona virus COVID-19 cases D614G variant demonstrated Efficacy genomic Genomic surveillance hamster hamsters Host immune response immune response India International isolate Isolation Lineage neutralization neutralized next generation sequencing P.2 variant P2 variant pathogenicity performed reduction reduction in respiratory respiratory tract returned rising SARS-CoV-2 SARS-CoV-2 genomic surveillance Sequencing sera Severe acute respiratory syndrome severe lung pathology Swab the vaccine United Kingdom variant variants Vero CCL81 cell Vero CCL81 cells viral replication virus virus isolation was performed weight loss
[DOI] 10.1016/j.jiph.2021.12.009 PMC 바로가기 [Article Type] Article

A quantitative assay for detection of SARS-CoV-2 neutralizing antibodies

SARS-CoV-2 중화 항체 검출을 위한 정량 분석

Article

Published on 2022-02-012022-09-11
Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술,

[키워드] 95% CI Alpha analyzed antibody Chorus Concordance COVID-19 Critical cross reaction diagnosis of COVID-19 diagnostic assay evaluate evaluated False negative False positives human serum IgA IgG IgM immunoassay Infection neutralization Neutralizing Neutralizing antibodies neutralizing antibody no significant differences other respiratory infection other respiratory infections patients positive Post-infection quantitative assay quantitative determination respiratory respiratory infections SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody SARS-CoV-2 virus sensitivity Sensitivity and specificity sera serological assays significant difference significant differences specific antibodies specific antibody specificity subjects symptomatic tracer Trio uninfected vaccination value variants virus were used
[DOI] 10.1016/j.jcv.2021.105064 PMC 바로가기 [Article Type] Article

Persistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortality

COVID-19에서 지속적으로 상승된 보체 대체 경로 바이오마커는 저산소혈증과 상관관계가 있으며 병원 내 사망률을 예측합니다

Article

Published on 2022-02-012022-09-11
Journal: Medical Microbiology and Immunology [Category] COVID19(2023년), MERS, SARS, 바이오마커,

[키워드] Activation Alternative pathway analyzed Biomarker C-reactive protein C5a cause complement Complement activation coronavirus disease Coronavirus disease 2019 correlations COVID-19 COVID-19 patient elevated enzyme enzyme-linked immunosorbent assays Evidence Factor Factor B ferritin healthy control healthy controls Hypoxemia ICU ICU admission IL-6 Immunity in-hospital mortality independent predictor Inflammatory response Innate Innate immunity lectin Level Lung disease marker measure Mortality Multi-organ damage overactivation pathway Patient patient sera predict prospectively studied quantified reduction Respiratory function risk SC5b-9 sera Serum level severely ill COVID-19 patients severity significantly sustained the patient
[DOI] 10.1007/s00430-021-00725-2 PMC 바로가기 [Article Type] Article

Humoral and cell-mediated response against SARS-CoV-2 variants elicited by mRNA vaccine BNT162b2 in healthcare workers: a longitudinal observational study

의료 종사자에서 mRNA 백신 BNT162b2에 의해 유발된 SARS-CoV-2 변이체에 대한 체액 및 세포 매개 반응: 종단적 관찰 연구

Observational Study

Published on 2022-02-012022-09-11
Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration affected antibody Antibody Response BNT162b2 BNT162b2 vaccine cell-mediated response coronavirus detectable dose effective elicit elicited evaluated exposure to Frequency healthcare healthcare worker humoral Humoral response Increased Increased immunogenicity investigated less mRNA mRNA BNT162b2 vaccine mRNA vaccine Neutralizing antibodies neutralizing antibody no significant difference positive reference strain respiratory Responder responders SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants second dose second dose of vaccine sera severe acute respiratory syndrome Coronavirus Strains subject subjects subset sustained T cell T cells T-cell T-cell Response T-cell responses tested the SARS-CoV-2 the vaccine vaccination Vaccine variant variants Viral viral variant Viral variants
[DOI] 10.1016/j.cmi.2021.09.016 PMC 바로가기 [Article Type] Observational Study

Inactivated Rabies Virus Vectored MERS-Coronavirus Vaccine Induces Protective Immunity in Mice, Camels, and Alpacas

Immunology

Published on 2022-01-312022-11-01
Journal: Frontiers in Immunology [Category] COVID-19,

Glycosylation and Serological Reactivity of an Expression-enhanced SARS-CoV-2 Viral Spike Mimetic

발현이 강화된 SARS-CoV-2 바이러스 스파이크 모방체의 당화 및 혈청학적 반응성

Research Article

Published on 2022-01-302022-09-10
Journal: Journal of Molecular Biology [Category] MERS, SARS, 변종, 진단, 치료기술,

[키워드] Abstract analysed Analysis antibody antigenic capture changes in clinical sample clinical samples COVID-19 patient COVID-19 patients detect discrepancies exhibit expression Extensive feature globe glycoprotein Glycoproteins glycosylation HexaPro IgA IgG IgM response IgM responses impacted include infected individual infected individuals Mimetic N-linked glycan N-linked glycans N-linked glycosylation observation performed Perturbation prefusion conformation proline proline substitution Protein protein structure reactivity S protein SARS-CoV-2 SARS-CoV-2 S SARS-CoV-2 S protein SARS-CoV-2 spike sera serological serological activity serological assessment serological studies serology spike stability Substitution substitutions trimeric spike Variation variations Viral viral glycoprotein viral glycoproteins virus viruses
[DOI] 10.1016/j.jmb.2021.167332 PMC 바로가기 [Article Type] Research Article