Effect of vaccination on household transmission of SARS-CoV-2 Delta variant of concern우려되는 SARS-CoV-2 Delta 변이체의 가정 전염에 대한 예방접종의 효과Article Published on 2022-06-302022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, [키워드] Breakthrough infection breakthrough infections concern Contact Delta delta variant Effect Effective vaccines Effectiveness exhibited household contacts household transmission individual Infection infectiousness National PROTECT public health reduce reducing SARS-CoV-2 SARS-COV-2 infection secondary case seeking susceptibility susceptibility to infection the vaccine transmission of SARS-CoV-2 vaccination Vaccinations Vaccine Viral load [DOI] 10.1038/s41467-022-31494-y PMC 바로가기 [Article Type] Article
Initial viral cycle threshold values in patients with COVID-19 and their clinical significanceArticle Published on 2022-06-282023-07-09 Journal: European Journal of Medical Research [Category] COVID19(2023년), [키워드] Coronavirus disease 2019 COVID-19 cycle threshold SARS-CoV-2 Viral load [DOI] 10.1186/s40001-022-00729-5 PMC 바로가기
SARS-CoV-2 Viral Load Analysis at Low and High Altitude: A Case Study from EcuadorArticle Published on 2022-06-282023-07-09 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), [키워드] COVID-19 cycle threshold (Ct) high altitude hypoxia RT-PCR SARS-CoV-2 Viral load [DOI] 10.3390/ijerph19137945 PMC 바로가기
Assessment of the frequency of coughing and sneezing triggered by nasopharyngeal swabbing in the pandemic settingObservational Study Published on 2022-06-272022-10-04 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 임상, [키워드] aerosol Aerosols age assessment chi-square test Consensus Contact Contamination coughing Defense develop evaluated event Frequency generate individual individuals Infection limit mucosa Nasopharyngeal swab nasopharyngeal swabbing no significant difference Observational cohort study Occurrence pandemic participant Particles persistence Personal protective equipment positive PPE Prevalence Prospective reported risk RT-PCR SARS-CoV-2 SARS-CoV-2 positive individuals Sex significant difference specimen Spread tested Testing the SARS-CoV-2 Trigger triggered variety Ventilation Viral load [DOI] 10.1038/s41598-022-14755-0 PMC 바로가기 [Article Type] Observational Study
Safety and efficacy of convalescent plasma for severe COVID-19: a randomized, single blinded, parallel, controlled clinical study중증 COVID-19에 대한 회복기 혈장의 안전성 및 효능: 무작위, 단일 맹검, 병렬, 대조 임상 연구Randomized Controlled Trial Published on 2022-06-272022-09-11 Journal: BMC Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, [키워드] 95% CI adjusted Admission anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 S1 IgG antibodies antibody antibody levels assigned benefit blinded clinical clinical study clinical trial conducted controlled clinical study convalescent plasma coronavirus disease Coronavirus disease 2019 COVID-19 CP plus standard therapy discharge dose early stage early stages Efficacy Estimated evaluate evaluated Follow-up hospital Hospitalization IgA IgA antibodies IgA antibody IgG increase in intensive care intensive care unit admission less mechanical ventilation Mortality MOST pandemic participant Patient patients per-protocol analysis plasma Primary outcome Primary outcomes Randomized receive reduce reduction reduction in S1 IgG Safe Safety SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants secondary outcome Secondary outcomes Seven severe coronavirus disease severe COVID-19 ST alone ST group Standard therapy symptoms onset the disease the SARS-CoV-2 the WHO therapeutic option titers transfused transfused plasma transfusion treat Variability variant Viral Viral load viral load reduction was obtained [DOI] 10.1186/s12879-022-07560-7 PMC 바로가기 [Article Type] Randomized Controlled Trial
Modeling recapitulates the heterogeneous outcomes of SARS-CoV-2 infection and quantifies the differences in the innate immune and CD8 T-cell responses between patients experiencing mild and severe symptoms모델링은 SARS-CoV-2 감염의 이질적인 결과를 요약하고 경증 및 중증 증상을 경험하는 환자 간의 타고난 면역 및 CD8 T 세포 반응의 차이를 정량화합니다.Article Published on 2022-06-272022-09-11 Journal: PLoS Pathogens [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory distress applied Arm ARMS CD8 T-cell CD8 T-cell response CD8 T-cell responses clinical observations concert cure dataset death elicit empirical evidence entire spectrum estimate exhibiting feature heterogeneous heterogeneous outcome immune implication in viral indicated Infection innate immune innate immune response Intervention mathematical mathematical model Mild modeling Occurrence offered outcome outcomes parameter Patient provided Quantitative recrudescence respiratory distress SARS-CoV-2 SARS-COV-2 infection severe disease Severe infection severe symptom Symptom T-cell Response Variability Viral load Viral variants without symptom [DOI] 10.1371/journal.ppat.1010630 PMC 바로가기 [Article Type] Article
Effective high-throughput RT-qPCR screening for SARS-CoV-2 infections in children소아에서 SARS-CoV-2 감염에 대한 효과적인 고처리량 RT-qPCR 스크리닝Article Published on 2022-06-252022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] Alpha Alpha variant approach children class correlated delta variant Deprivation diagnosed effective Frequency Germany incidence indicated individual Infection infection control Local Non-invasive positive powerful tool RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 surveillance SARS-CoV-2 testing School Schools sensitivities sensitivity statistical Support Surveillance tested variant Viral load viral loads [DOI] 10.1038/s41467-022-30664-2 PMC 바로가기 [Article Type] Article
Associated Psychological Factors of Viral Load among Self-Isolating Nigerian COVID-19 PatientsArticle Published on 2022-06-242023-07-09 Journal: West African journal of medicine [Category] COVID19(2023년), [키워드] Corona virus COVID-19 Psychological correlates SARS-CoV-2 Viral load
Intranasal vaccination of hamsters with a Newcastle disease virus vector expressing the S1 subunit protects animals against SARS-CoV-2 diseaseS1 소단위를 발현하는 뉴캐슬병 바이러스 벡터를 사용한 햄스터의 비강내 예방접종은 SARS-CoV-2 질병으로부터 동물을 보호합니다Article Published on 2022-06-202022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 변종, 비임상, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administer administration animals breath claimed coronavirus coronavirus disease Coronavirus disease-19 COVID-19 Critical effective Efficacy elicited expressing hamster hamsters human clinical trial humoral immune responses immune responses long term lung damage mice Neutralizing antibodies newcastle disease virus pandemic phase prevented PROTECT Protective recent recorded recorded history reduced respiratory respiratory tract Safe SARS-CoV-2 SARS-CoV-2 disease severe acute respiratory syndrome Coronavirus short term significantly the disease the S1 subunit vaccination Vaccine vaccine candidate variant vectored vaccine Viral Viral load while [DOI] 10.1038/s41598-022-13560-z PMC 바로가기 [Article Type] Article
Astodrimer sodium antiviral nasal spray for reducing respiratory infections is safe and well tolerated in a randomized controlled trial호흡기 감염 감소를 위한 아스토드리머 나트륨 항바이러스 비강 스프레이는 무작위 대조 시험에서 안전하고 내약성이 우수합니다.Randomized Controlled Trial Published on 2022-06-172022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 임상, 치료기술, 치료제, [키워드] absorbed Absorption Administered administration adverse event All participants Antiviral applied clinical clinical investigation clinical trial clinically Cohort Community community acquired dendrimer double-blinded Effects examination finding examination findings exploratory exposure to followed by four times daily Frequency healthy volunteer help in vitro Infection initial intensity Intensive Mild nasal Nasal cavity nasal mucosa Nasal spray New nostril occurred other respiratory virus Other respiratory viruses participant Placebo placebo-controlled primary endpoint product Randomized Randomized controlled trial receiving reduce reducing Registered registry respiratory infection respiratory virus Respiratory virus infections respiratory viruses Safe safety population SARS-CoV-2 serious AEs severity shown sodium spray Spread systemically TEAE TEAEs Tolerability Treatment Trial registration utility vaginal mucosa Viral load virucidal Withdrawal [DOI] 10.1038/s41598-022-14601-3 PMC 바로가기 [Article Type] Randomized Controlled Trial