Apigenin inhibits growth of the Plasmodium berghei and disrupts some metabolic pathways in micearticle Published on 2018-09-302024-09-01 Journal: Phytotherapy Research [Category] 말라리아, [키워드] apigenin cytotoxicity metabolic pathways Plasmodium berghei [Article Type] article
Lignans from Tujia Ethnomedicine Heilaohu: Chemical Characterization and Evaluation of Their Cytotoxicity and Antioxidant ActivitiesArticle Published on 2018-08-272023-08-30 Journal: Molecules [Category] E형 간염, [키워드] antioxidant chemical characterization cytotoxicity heilaohu lignans tujia ethnomedicine [DOI] 10.3390/molecules23092147 PMC 바로가기 [Article Type] Article
Characterization of peritoneal cells from cats with experimentally-induced feline infectious peritonitis (FIP) using RNA-seqResearch Article Published on 2018-08-072022-10-28 Journal: Veterinary Research [Category] Coronavirus, [키워드] activated addition Allograft Alter Analysis APN Apoptosis Autoimmune disorders B cell Cell change characterization collected cytotoxicity DC-SIGN death deregulated disease Diseases dissemination down-regulated enrichment analysis Fever fold healthy Host immune complex indicated Interaction involved KEGG L-SIGN Laboratory less lymphopenia Macrophage mature macrophages MHC I mRNA mRNA expression NK cell other coronavirus pathogen pathway peritoneal macrophage populations receptor rejection RNA expression RNA-Seq serotype Signaling significantly Th1 Th2 transcript upregulated virus were infected [DOI] 10.1186/s13567-018-0578-y PMC 바로가기 [Article Type] Research Article
Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteersArticle Published on 2018-06-282024-09-04 Journal: Clinical immunology (Orlando, Fla.) [Category] 대상포진, [키워드] cytotoxicity healthy volunteers interferon-γ Natural killer cells T cells Tofacitinib [DOI] 10.1016/j.clim.2018.03.002 PMC 바로가기 [Article Type] Article
Decreased Siglec-9 Expression on Natural Killer Cell Subset Associated With Persistent HBV ReplicationOriginal Research Published on 2018-05-302023-06-03 Journal: Frontiers in Immunology [Category] B형 간염, Fulltext, [키워드] Chronic Hepatitis B cytokine synthesis cytotoxicity NK Siglec-9 [DOI] 10.3389/fimmu.2018.01124 PMC 바로가기 [Article Type] Original Research
Synthesis and Evaluation of Antiplasmodial Activity of 2,2,2-Trifluoroethoxychalcones and 2-Fluoroethoxy Chalcones against Plasmodium falciparum in Culture2,2,2-트리플루오로에톡시칼콘과 2-플루오로에톡시칼콘의 합성과 평가: 배양된 말라리아 원충 플라스모디움 팔시파룸에 대한 항말라리아 활성을 중심으로Article Published on 2018-05-142024-08-11 Journal: Molecules [Category] 말라리아, [키워드] Antiplasmodial activity Artemisinin combination therapy cytotoxicity fluoroethoxychalcones Plasmodium falciparum (3D7) [DOI] 10.3390/molecules23051174 PMC 바로가기 [Article Type] Article
Novel Peroxides as Promising Anticancer Agents with Unexpected Depressed Antimalarial ActivityArticle Published on 2018-05-082024-08-27 Journal: ChemMedChem [Category] 말라리아, [키워드] Cancer cytotoxicity malaria ozonides peroxides.
MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cellsResearch Article Published on 2018-03-222022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] addition antigen presenting cell antigen presenting cells antigen-presenting cell antiviral activity Antiviral effect antiviral efficacy antiviral response APC APCS assays cell lines cells chemokine Chloroquine clinical study Compound cytotoxicity dendritic cell determine drug evaluate evaluated Fatality rate highlight Human human monocyte-derived macrophage immature immortalized cell lines Inflammatory cytokine MDM MERS MERS-CoV MERS-CoV infection Middle East Pathogenesis primary cells Proinflammatory cytokine protective immune response public health Replication respiratory syndrome coronavirus robust severe respiratory disease tested therapeutic option Treatment upregulation virulence while [DOI] 10.1371/journal.pone.0194868 PMC 바로가기 [Article Type] Research Article
Quaternized chitosan nanoparticles loaded with the combined attenuated live vaccine against Newcastle disease and infectious bronchitis elicit immune response in chicken after intranasal administrationResearch Article Published on 2017-10-132022-10-31 Journal: Drug Delivery [Category] Coronavirus, MERS, [키워드] 1:1 administration Ammonium Antigen antigens Bioactivity bronchitis cellular chloride CMC cytotoxicity disease Diseases drug elicit exhibited humoral IBV IFN-γ IgA antibodies IL-2 IL-4 immune response immunization in vitro indicated induce Infection Infectious bronchitis initial interferon-γ intranasal intranasal delivery intranasally lymphocyte mucosal mucosal immune N-2-hydroxypropyl trimethyl ammonium chloride chitosan nanoparticles Newcastle disease proliferation promoted Release released Respiratory disease responses resulting significantly SOTA stability titers of IgG Vaccine vaccine adjuvant virulent [DOI] 10.1080/10717544.2017.1388450 PMC 바로가기 [Article Type] Research Article
Evaluating the Effects of an Organic Extract from the Mediterranean Sponge Geodia cydonium on Human Breast Cancer Cell LinesArticle Published on 2017-10-092024-09-02 Journal: International Journal of Molecular Sciences [Category] 대상포진, [키워드] Breast cancer Cytokines cytotoxicity metabolomics sponges [DOI] 10.3390/ijms18102112 PMC 바로가기 [Article Type] Article