MUC22, HLA-A, and HLA-DOB variants and COVID-19 in resilient super-agers from BrazilArticle Published on 2022-10-252023-07-10 Journal: Frontiers in Immunology [Category] COVID19(2023년), [키워드] COVID-19 HLA Human Leukocyte Antigens immune response major histocompatibility complex (MCH) MUC22 resistant genetic variants. SARS-CoV-2 [DOI] 10.3389/fimmu.2022.975918 PMC 바로가기
Humoral immunity and transcriptome differences of COVID-19 inactivated vacciane and protein subunit vaccine as third booster dose in humanArticle Published on 2022-10-212022-11-16 Journal: Frontiers in Immunology [Category] 변종, 유전자 메커니즘, [키워드] analyzed antibody approach booster booster dose caused correlation COVID-19 differentially expressed gene dose effective Effectiveness Efficacy Factor Health help Heterologous homologous humoral humoral immune response Humoral immunity immune Immune escape immune response Immunity immunization inactivated Inactivated vaccine indicated innate immune function innate immune pathways participant Perspective Prevalence protein subunit vaccine provided significantly Support System third booster vaccine transcriptional response Transcriptome transcriptome analysis transcriptomic analysis vaccination Vaccine variants of concern VOCs with COVID-19 [DOI] 10.3389/fimmu.2022.1027180 PMC 바로가기
Humoral and cellular immune responses to CoronaVac up to one year after vaccinationArticle Published on 2022-10-212022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] all subject Antibody Response Antiviral CD4^{+} T cell cellular Cellular immune response cellular response clinical trial CoronaVac cytokine production cytokine profile defined effector memory evaluated follicular humoral Humoral response immune immune memory immune response impacted Inactivated vaccine individual induce memory Older peaked Phase 3 response SARS-CoV-2 SARS-CoV-2-specific IgG SARS-CoV-2-specific immune responses second dose sustained T cell activation T cell phenotype Tfh Th2 vaccination vaccine dose vaccinees [DOI] 10.3389/fimmu.2022.1032411 PMC 바로가기
Humoral immune response against BNT162b2 mRNA COVID-19 vaccine in patients with rheumatic disease undergoing immunosuppressive therapy: A Japanese monocentric studyArticle Published on 2022-10-212022-11-15 Journal: Medicine [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome addition Analysis analyzed Antibody titer attenuate Baricitinib BNT162b2 mRNA BNT162b2 mRNA vaccination BNT162b2 vaccine Combination controls coronavirus coronavirus disease COVID-19 COVID-19 vaccine disease domain dose Glucocorticoids healthy volunteer humoral immune response immunomodulatory Immunosuppressant immunosuppressants immunosuppressive immunosuppressive agent Immunosuppressive medication impair inhibitor inhibitors interleukin-17 interleukin-6 investigated Japanese Kagawa methotrexate much lower Necrosis of BNT162b2 Outpatient Patient patients treated reduced rheumatic disease SARS-CoV-2 SARS-CoV-2 spike protein second dose serum serum antibody significantly significantly lower Spike protein the patient therapeutic agent Treatment university Vaccine [DOI] 10.1097/MD.0000000000031288 PMC 바로가기
A Mendelian randomization study of genetic predisposition to autoimmune diseases and COVID-19Article Published on 2022-10-212022-11-16 Journal: Scientific Reports [Category] 변종, [키워드] Analysis Antigen association Autoimmune disease Autoimmune diseases biliary cirrhosis concern coronavirus disease COVID-19 COVID-19 susceptibility Diabetes Mellitus disease examined Genetic predisposition Genetic variant Genome-wide association studies Genome-wide association study hospitalized COVID-19 immune response Infection juvenile idiopathic arthritis leukocyte mendelian randomization Mendelian randomization analysis multiple sclerosis performed rheumatoid arthritis severe COVID-19 severity severity of COVID-19 similarities susceptibility systemic lupus erythematosus with COVID-19 [DOI] 10.1038/s41598-022-22711-1 PMC 바로가기
Construction and evaluation of a self-replicative RNA vaccine against SARS-CoV-2 using yellow fever virus repliconArticle Published on 2022-10-202022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome antibody Antigen C57BL/6 caused cells co-expressed construction coronavirus coronavirus disease COVID-19 effective vaccine Efficacy Electroporation elicit ENCODE ENhance evaluated Fever gene encoding Host host genome immune response Immunity IMPROVE Infection Innate immunity kidney mice mRNA vaccine pandemic Protein qRT-PCR Replication replicon responses RNA RNA vaccine robust S protein expression Safe SARS-CoV-2 significantly higher single dose Specific T-cell response T-cell Response the S protein Vaccine vaccine administration vaccine platform virus [DOI] 10.1371/journal.pone.0274829 PMC 바로가기
CASA: a comprehensive database resource for the COVID-19 Alternative Splicing AtlasArticle Published on 2022-10-202022-11-15 Journal: Journal of Translational Medicine [Category] 유전자 메커니즘, 치료기술, 치료제, [키워드] affected alteration Analysis Atla cell line conditions COVID-19 database dataset Diseases drug-target interaction event events facilitate functional annotation help host cell human cell identify immune response IMPROVE Infectious disease mechanism mechanisms Organoid performed platform profile Protein protein expression provided Quantitative data regulate Regulatory Research resource RNA RNA-seq dataset severity splicing tissues transcriptional virus [DOI] 10.1186/s12967-022-03699-8 PMC 바로가기
Advances in Biosensing Technologies for Diagnosis of COVID-19Article Published on 2022-10-202022-11-15 Journal: Biosensors [Category] COVID19(2023년), SARS, 치료기술, [키워드] advance Biomarker biosensor biosensors carrier Community contagiousness COVID-19 COVID-19 biomarkers COVID-19 diagnosis COVID-19 pandemic Diagnosis diagnosis of COVID-19 Diagnostic biomarkers diagnostic test diagnostics Disadvantages high mortality immune response impacted Infection Major number of sample pathogenesis of COVID-19 point-of-care proinflammatory provide Research RT-qPCR SARS-CoV-2 specimen Spread technology time-consuming traditional method viral genomes Viral proteins [DOI] 10.3390/bios12100898 PMC 바로가기
The possible importance of the antioxidants and oxidative stress metabolism in the emerging monkeypox disease: An opinion paperArticle Published on 2022-10-202023-06-10 Journal: Frontiers in Public Health [Category] Fulltext, 원숭이두창, [키워드] antioxidant enzymes antioxidant molecules immune response Monkeypox MPXV infection oxidative stress [DOI] 10.3389/fpubh.2022.1001666 PMC 바로가기
SARS-CoV-2 anti-spike antibodies after a fourth dose of COVID-19 vaccine in adult solid-organ transplant recipientsArticle Published on 2022-10-192022-11-15 Journal: Vaccine [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] age anti-spike antibody antibodies Antibody titer booster conducted COVID-19 COVID-19 vaccine detectable dose doses fourth dose had more humoral immune response IQR kidney transplant recipients liver transplant no statistical difference Organ transplant participant patients proportion receiving recipient recipients regimen retrospective SARS-CoV-2 SARS-CoV-2 vaccine significantly higher solid-organ transplant Solid-organ transplantation SOT tested third dose vaccination Vaccine vaccine doses vaccine injection [DOI] 10.1016/j.vaccine.2022.08.065 PMC 바로가기