Assessing efficacy of antiviral therapy for COVID-19 patients: A case study on remdesivir with bayesian synthesis design and multistate analysisCOVID-19 환자에 대한 항바이러스 요법의 효능 평가: 베이지안 합성 설계 및 다중 상태 분석을 사용한 렘데시비르에 대한 사례 연구Article Published on 2021-06-012022-09-11 Journal: Journal of the Formosan Medical Association = Taiw [Category] SARS, 치료제, [키워드] 95% CI Analysis antiviral therapy applied Assessing Bayesian Bayesian synthesis sequential design case study clinical Clinical efficacy COVID-19 COVID-19 patient death discharge Disease progression Efficacy empirical evidence Evidence High-risk patients Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients medium Mortality outcome outcome measure outcome measures Patient patients with COVID-19 progression reducing reducing mortality reduction Remdesivir required risk of death sequential design significantly shorter standard care group statistically significant subsequent therapy treated treated patient Trial Two-arm [DOI] 10.1016/j.jfma.2021.04.026 PMC 바로가기 [Article Type] Article
Exhaled SARS-CoV-2 quantified by face-mask sampling in hospitalised patients with COVID-19코로나19로 입원한 환자의 안면 마스크 샘플링으로 정량화된 SARS-CoV-2 호기Article Published on 2021-06-012022-09-11 Journal: The Journal of Infection [Category] SARS, 치료기술, [키워드] 95% CI adjusted Analysis asked association Asymptomatic breath collected coronavirus disease coronavirus disease-2019 COVID-19 demographic detect Deterioration disease dissolution driven by early disease effective FIVE fixed followed by Genome highest highlighting hospital hospitalised hospitalised patient Hospitalised patients Human individual IQR ISARIC Linear regression analysis magnitude Mask median median age medium Mortality multivariable nasopharyngeal sample Nasopharyngeal samples Nasopharyngeal swab negative NHS NPs participant Patient pattern positive processed quantified quantity radiological removal respiratory respiratory route respiratory symptom respiratory symptoms RT-qPCR sampling SARS-CoV-2 SARS-CoV-2 RNA severe disease shown strip symptom onset transmission of SARS-CoV-2 Trust university Viral load viral loads virus with COVID-19 [DOI] 10.1016/j.jinf.2021.03.018 PMC 바로가기 [Article Type] Article
Assessing the efficiency of Malaysia health system in COVID-19 prevention and treatment responseCOVID-19 예방 및 치료 대응에서 말레이시아 의료 시스템의 효율성 평가Article Published on 2021-06-012022-09-11 Journal: Health care management science [Category] SARS, 치료기술, [키워드] Analysis Assessing Care categories combating Community confirmed cases country COVID-19 COVID-19 prevention and treatment death death case Efficiency Efficiency measurement Government Health crisis health system high-density highest implementation include inefficiency initiated life-threatening low-density Malaysia Medical care medium network Network DEA. pandemic performed population density positive provided public health public health crisis rapid response resource Result Surveillance Treatment response variable was performed were used [DOI] 10.1007/s10729-020-09539-9 PMC 바로가기 [Article Type] Article
Developments in Treatment Methodologies Using Dendrimers for Infectious DiseasesReview Published on 2021-05-312022-10-30 Journal: Molecules [Category] COVID-19, SARS, [키워드] antibody Antimicrobial therapy Antiviral agents antiviral therapy Bacteria biochemical Compound contrast agent dendrimer dendrimers development diagnostic diagnostics Diseases drug delivery genetic material Infectious disease Infectious diseases macromolecules medium methodology MRI Nanoparticles parasites peptide polymers potential therapy structural property substrate therapeutic Transport Vaccine viruses [DOI] 10.3390/molecules26113304 PMC 바로가기 [Article Type] Review
Formulation of a Composite Nasal Spray Enabling Enhanced Surface Coverage and Prophylaxis of SARS‐COV‐2Research Article Published on 2021-05-312022-10-28 Journal: Advanced Materials (Deerfield Beach, Fla.) [Category] COVID-19, SARS, [키워드] acute respiratory syndrome antiviral properties block carrageenan cells Characteristics characterized clearance Complete inhibition Composite Coverage COVID‐19 distribution Enabling enhanced Formulation formulation engineering high risk Infection Intervention mechanism medium nasal nasal epithelium Nasal Sprays pathogen pathway Pathways physical Prevent Prophylaxis PROTECT resulting SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 shown spray Spread surface Transmission upper respiratory Vero cells virus virus uptake [DOI] 10.1002/adma.202008304 PMC 바로가기 [Article Type] Research Article
A Rare Case of SARS-CoV-2-Induced Microscopic PolyangiitisInternal Medicine Published on 2021-05-262022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute COVID-19 Acute kidney injury acute respiratory syndrome AKI alveolar Analysis ANCA associated vasculitis antibody Antigen autoantibody Blood cellular circulating cytokine Clinical improvement contribute coronavirus Corticosteroid COVID 19 COVID-19 CT chest Cytokine storm cytoplasmic diagnosed Diagnosis differential diagnosis diffuse alveolar hemorrhage dysregulated immune response elevated female global pandemic glomerulonephritis (gn) hemoptysis hemorrhage Hyperactivation immune-cell immunosuppressive infected with SARS-CoV-2 Infection large vessel medium Microscopic Microscopic Polyangiitis Multiorgan multiple organs pathogen pathology pathophysiology Patient polyangiitis positive post-mortem biopsy Pulmonary alveolar proteinosis renal renal biopsy reported rituximab SARS-CoV-2 SARS-COV-2 infection serum creatinine Shortness of breath the patient therapy thrombotic event Trigger unique Urine Vascular Vascular injury Vasculitis [DOI] 10.7759/cureus.15259 PMC 바로가기 [Article Type] Internal Medicine
Learning from previous lockdown measures and minimising harmful biopsychosocial consequences as they end: A systematic review이전의 봉쇄 조치에서 배우고 종료 시 유해한 생물심리사회적 결과 최소화: 체계적인 검토Research Theme 1: COVID-19 Pandemic Published on 2021-05-222022-09-10 Journal: Journal of Global Health [Category] 임상, [키워드] alcohol analysed applied behavioural children closure consequence Consequences coronavirus disease Coronavirus disease 2019 COVID-19 database defined Deterioration discrepancies distress Effect Efficacy eligible English Establishing Evidence examined for inclusion French group Health care health care workers immediate effect immediate effects impacts inception Increased independent individuals information Inpatients Intervention Isolation Italian lack learning Local lockdown manifested measure Measures medium mental health mitigate modifications National outbreak Outbreaks outcome OVID Participants physical distancing progression Psychiatric psychiatric diagnoses Psychological distress PsycINFO public health quarantine randomisation reaction reference remains uncertain required Result searched secondary to social distancing study heterogeneity Supporting systematic review trauma Web of Science were excluded Workplace [DOI] 10.7189/jogh.11.05008 PMC 바로가기 [Article Type] Research Theme 1: COVID-19 Pandemic
Strategies for the Production of Soluble Interferon-Alpha Consensus and Potential Application in Arboviruses and SARS-CoV-2Article Published on 2021-05-212022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] Alpha Amino acid analyzed Antiviral Antiviral effect application approach arbovirus Arboviruses Bacteria biological activity biopharmaceutical cells Clinical use Consensus COVID-19 Culture culture media E. coli Fh8 growth Healthcare system hydrolysis IFN-α IMPROVE in vitro model Inclusion inhibit medium Potential prevalent produced Production protein sequence purified Research SARS-CoV-2 SARS-CoV-2 virus infection solubility tag Strategy susceptible temperature treat virus multiplication viruses was tested Zika [DOI] 10.3390/life11060460 PMC 바로가기 [Article Type] Article
Work Resumption Rate and Migrant Workers’ Income During the COVID-19 PandemicPublic Health Published on 2021-05-212022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Affect Analysis average Baidu Chinese coronavirus COVID-19 COVID-19 pandemic decrease expected Gray help income Lantern Festival lockdown lockdowns medium MES migrant worker Model pandemic predict predicted public health crisis Rate scenario analysis Support variable work work resumption rate worker [DOI] 10.3389/fpubh.2021.678934 PMC 바로가기 [Article Type] Public Health
COVID-19 pandemic and stability of stock market—A sectoral approachResearch Article Published on 2021-05-202022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] affected analyzed approach Cluster Clustering condition country COVID-19 COVID-19 pandemic criterion drastic exchange Health care system identify investigated medium observé pandemic Prevent remained Research Shock spread of COVID-19 stability stock Volume ward Warsaw [DOI] 10.1371/journal.pone.0250938 PMC 바로가기 [Article Type] Research Article