sera – Page 28 – Communicable Diseases Research

Quantitative measurement of IgG to SARS‐CoV‐2 antigens using monoclonal antibody‐based enzyme‐linked immunosorbent assays

Original Article

Published on 2022-01-302022-10-31
Journal: Clinical & Translational Immunology [Category] COVID-19,

Aggregation of high‐frequency RBD mutations of SARS‐CoV‐2 with three VOCs did not cause significant antigenic drift

Research Article

Published on 2022-01-282022-10-04
Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

Humoral anti-SARS-CoV-2 immune response after two doses of Comirnaty vaccine in nursing home residents by previous infection status

이전 감염 상태에 따른 요양원 거주자의 Comirnaty 백신 2회 접종 후 체액성 항-SARS-CoV-2 면역 반응

Article

Published on 2022-01-242022-09-11
Journal: Vaccine [Category] SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered Adults advent anti-SARS-CoV-2 Anti-spike antibody arbitrary units B.1.1.7 B.1.351 binding clinical trial clinical trials Cohort coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 dose effective humoral Humoral response Humoral vaccine response IgG immune response individual Infection intensity median morbidity and mortality Neutralizing antibodies neutralizing antibodies titer neutralizing antibodies titers not decreased nursing home Older Older adults P.1 variant Patient Pfizer-BioNTech positive pre-vaccination quantified question raise RBD reduced resident respiratory SARS-CoV-2 sera serological Serological assay Seropositivity severe acute respiratory syndrome Coronavirus significantly significantly higher tested Vaccine wild-type
[DOI] 10.1016/j.vaccine.2021.11.086 PMC 바로가기 [Article Type] Article

Omicron: A Heavily Mutated SARS-CoV-2 Variant Exhibits Stronger Binding to ACE2 and Potently Escapes Approved COVID-19 Therapeutic Antibodies

Omicron: 심하게 돌연변이된 SARS-CoV-2 변이체는 ACE2에 대한 더 강한 결합을 나타내며 승인된 COVID-19 치료 항체를 잠재적으로 탈출

Immunology

Published on 2022-01-242022-09-11
Journal: Frontiers in Immunology [Category] SARS, 변종, 진단,

[키워드] ACE2 ACE2 binding antibodies antibody approved Beta bind binding binding energy clinical trials complex conserved contribute COVID-19 COVID-19 therapy E484K electrostatic epitope escape etesevimab facilitate FDA free energy Gamma Hong Kong Immune escape immune response Infection investigated mAb mAbs monoclonal antibodies monoclonal antibody Mutagenesis Mutation neutralization neutralize new SARS-CoV-2 omicron Phase III clinical trials potency Protein RBD Receptor binding Receptor-binding domain reported SARS-CoV-2 sera significantly Sotrovimab South Africa spike mutations Spike protein Spread Substitution substitutions T478K the RBD the receptor-binding domain the Spike therapeutic therapeutic antibodies therapy Transmissibility vaccinee vaccinees variant variants virus
[DOI] 10.3389/fimmu.2021.830527 PMC 바로가기 [Article Type] Immunology

Low Neutralizing Antibody Titers against the Mu Variant of SARS-CoV-2 in 31 BNT162b2 Vaccinated Individuals in Colombia

Communication

Published on 2022-01-242022-10-28
Journal: Vaccines [Category] COVID-19,

[키워드] acute respiratory syndrome Antiviral treatment BNT162b2 calculated Concentration coronavirus coronavirus disease COVID-19 Culture determine epidemiological evaluate FIVE Gamma gamma (P.1) variant generate genetic marker greater individual infectious dose Laboratory lack less Mu (B.1.621) variant Mutation neutralization titer Neutralizing antibodies neutralizing antibody Neutralizing antibody response Neutralizing antibody titer Patient performed predominant SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sera serial dilution significantly lower Spike protein Surveillance susceptible TCID50 the spike protein tissue titer undetectable vaccine-induced antibodies Vaccines variant variants virulence volunteers
[DOI] 10.3390/vaccines10020180 PMC 바로가기 [Article Type] Communication

Omicron variant showed lower neutralizing sensitivity than other SARS-CoV-2 variants to immune sera elicited by vaccines after boost

오미크론 변이체는 부스트 후 백신에 의해 유도된 면역 혈청에 대해 다른 SARS-CoV-2 변이체보다 낮은 중화 민감도를 나타냈습니다.

Coronaviruses

Published on 2022-01-242022-09-10
Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단,

[키워드] B.1.1.529 BBIBP-CorV Beta boost booster booster vaccination COVID-19 Delta dose elicited escaped GMT GMTs Heterologous heterologous protein homologous homologous or heterologous immune Immune escape immune protection immunogenicity IMPROVE inactivated Inactivated vaccine Inactivated Vaccines limit multiple mutations neutralization neutralization ability neutralization activity Neutralizing neutralizing antibody omicron patients positive protein subunit vaccine prototype pseudotype Pseudotyped viruses quantitation raised reduction reported SARS-CoV-2 SARS-CoV-2 variant sensitivity sera significantly increased Subunit vaccine titre Vaccine variant VoC VOCs ZF2001
[DOI] 10.1080/22221751.2021.2022440 PMC 바로가기 [Article Type] Coronaviruses

Immunogenicity of a third dose viral-vectored COVID-19 vaccine after receiving two-dose inactivated vaccines in healthy adults

건강한 성인에게 2회 접종 불활화 백신을 접종한 후 3차 접종 바이러스 벡터 COVID-19 백신의 면역원성

Article

Published on 2022-01-242022-09-11
Journal: Vaccine [Category] SARS, 변종, 진단,

[키워드] anti-RBD Anti-spike AZD1222 B.1.1.7 B.1.351 B.1.617.2 booster booster dose completion CoronaVac COVID-19 COVID-19 vaccine delta variant demonstrated dose elicited enzyme enzyme-linked immunosorbent healthcare worker Healthcare workers healthy IgA IgG immune response immunogenicity Immunoglobulin immunoglobulins Inactivated vaccine Inactivated Vaccines individual neutralization test neutralizing activities Neutralizing activity participant Protein Public public health RBD RBD-specific IgG receiving recipient recipients resulting SARS-CoV-2 SARS-CoV-2 spike sera serum sample serum samples subset surrogate virus neutralization test tested Vaccine vaccinee Vaccines variant variant of SARS-CoV-2 variants variants of concern virus neutralization test Virus vector widespread wild type
[DOI] 10.1016/j.vaccine.2021.11.083 PMC 바로가기 [Article Type] Article

mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 omicron variant

mRNA-1273 및 BNT162b2 mRNA 백신은 SARS-CoV-2 오미크론 변이체에 대한 중화 활성을 감소시켰습니다

Article

Published on 2022-01-242022-09-11
Journal: Cell Reports Medicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody B.1.1.529 BNT162b2 mRNA vaccine booster booster dose coronavirus dose doses Immunity individual initial live-virus majority mRNA mRNA vaccines mRNA-1273 Mutation naïve individuals neutralization neutralization activity Neutralization assay Neutralizing activity Neutralizing antibody response neutralizing antibody responses observé omicron Omicron variant receiving reduced reduction reduction in required respiratory robust SARS-CoV-2 sera serum severe acute respiratory syndrome Coronavirus subject the SARS-CoV-2 vaccination Vaccinations Vaccine vaccine induced immunity.
[DOI] 10.1016/j.xcrm.2022.100529 PMC 바로가기 [Article Type] Article

Antibody Response of Combination of BNT162b2 and CoronaVac Platforms of COVID-19 Vaccines against Omicron Variant

Article

Published on 2022-01-212022-10-28
Journal: Vaccines [Category] COVID-19,

Regional and temporal coordinated mutation patterns in SARS-CoV-2 spike protein revealed by a clustering and network analysis

클러스터링 및 네트워크 분석에 의해 밝혀진 SARS-COV-2 스파이크 단백질의 지역 및 시간적 조정 돌연변이 패턴

Article

Published on 2022-01-212022-09-10
Journal: Scientific Reports [Category] SARS, 변종, 치료기술,