BNT162b2 Vaccination Elicits Strong Serological Immune Responses Against SARS-CoV-2 Including Variants of Concern in Elderly ConvalescentsBNT162b2 백신 접종은 노인 요양기의 우려 변종을 포함하여 SARS-CoV-2에 대한 강력한 혈청학적 면역 반응을 이끌어냅니다Observational Study Published on 2021-09-292022-09-11 Journal: Frontiers in Immunology [Category] SARS, 변종, 임상, 진단, [키워드] Against age analyzed anti-Spike IgG Antibody titer Antibody titers B.1.1.7 B.1.351 benefit binding domain BNT162b2 Care Comirnaty concern convalescent individual COVID-19 COVID-19-convalescent individual cross-reactive Efficacy elderly End End points Gender IgA titer IgA titers IgG titers immune response immune responses Including individual Long-term care MOST mRNA vaccine mutated neutralization capacity neutralization test Neutralizing neutralizing capacity P.1 pre-vaccination prospective observational cohort response SARS-CoV-2 SARS-CoV-2 receptor serological serum significantly higher strength Strong subject vaccination Vaccine vaccinees variants of concern VOCs [DOI] 10.3389/fimmu.2021.743422 PMC 바로가기 [Article Type] Observational Study
Agreement between commercially available ELISA and in-house Luminex SARS-CoV-2 antibody immunoassaysArticle Published on 2021-09-232022-10-04 Journal: Scientific Reports [Category] SARS, 진단, [키워드] agreement Blood coronavirus COVID-19 diagnostic diagnostic test diagnostics ELISA epidemiological evaluated external validation IgG Immunity immunoassay moderate Negative predictive value pandemic Positive predictive value pregnant women reached SARS-CoV-2 SARS-CoV-2 antibody sensitive assay sensitivity serological Severe respiratory distress specificity Stress Surveillance syndrome viral infection virus [DOI] 10.1038/s41598-021-98296-y PMC 바로가기 [Article Type] Article
Comprehensive Immune Profiling of a Kidney Transplant Recipient With Peri-Operative SARS-CoV-2 Infection: A Case Report수술 전후 SARS-CoV-2 감염이 있는 신장 이식 수혜자의 종합 면역 프로파일링: 증례 보고서Case Reports Published on 2021-09-222022-09-11 Journal: Frontiers in Immunology [Category] SARS, 유전자 메커니즘, 진단, [키워드] basiliximab cellular change Comprehensive COVID-19 COVID-19 infection Critical diagnosed Immune profile immune response immunological immunosuppressants Immunosuppression impair induction therapy kidney maintenance outcome performed positive Post-infection Profiling proteomic recipient report robust SARS-CoV-2 SARS-CoV-2 test serological significantly solid organ solid organ transplant symptomatic symptomatic COVID-19 the patient Transplant unique [DOI] 10.3389/fimmu.2021.753558 PMC 바로가기 [Article Type] Case Reports
Kinetics of SARS-CoV-2 Specific and Neutralizing Antibodies over Seven Months after Symptom Onset in COVID-19 PatientsResearch Article Published on 2021-09-222022-10-30 Journal: Microbiology Spectrum [Category] COVID-19, MERS, SARS, [키워드] 95% CI 95% confidence interval acute phase acute respiratory syndrome administration age anti-SARS-CoV-2 antibody antibodies antibody Characteristics China collected conducted convalescent COVID-19 patient Convalescent patients coronavirus coronavirus disease COVID-19 COVID-19 convalescent patient COVID-19 patient Dilution discharge discharged disease severity enrolled Evidence Factor Follow-up follow-up period follow-up time geometric mean titer GMT hospital IgG IgM IgM/IgG immune response inhibitory interquartile range Jiangsu Kinetics male median Month natural infection Neutralizing activity neutralizing antibody Onset participant Patient patients persistence plasma sample produced SARS-CoV-2 serological seropositive serum sample severity significantly higher significantly lower Specific Standard deviation symptom onset tested Vaccine virus dynamics with COVID-19 [DOI] 10.1128/Spectrum.00590-21 PMC 바로가기 [Article Type] Research Article
Serological Testing Reveals the Hidden COVID-19 Burden among Health Care Workers Experiencing a SARS-CoV-2 Nosocomial Outbreak혈청학적 검사를 통해 SARS-CoV-2 병원 발병을 경험한 의료 종사자들 사이에 숨겨진 COVID-19 부담이 드러났습니다.Research Article Published on 2021-09-222022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aerosol-generating procedure airway amplification antibody Antibody testing approach approaches burden Care chemiluminescent immunoassay Cluster coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 outbreak COVID-19 patient COVID-19 patients detect diagnose diagnosing diagnostic diagnostics Diseases globe Health Health care Health care system health care workers hidden hospital Host iceberg immune response immune responses Infection Infectious diseases Japan molecular NAAT neutralization test Noninvasive ventilation nucleic acid amplification testing observation occurred outbreak pandemic pathogen PCR portion respiratory risk Risk assessment SARS-CoV-2 SARS-CoV-2 nucleic acid SARS-CoV-2-specific antibodies Seroconversion serological Serological testing serology severe acute respiratory syndrome Coronavirus silent Spread Testing Transmission triggered Viral Viral detection virus neutralization test worker [DOI] 10.1128/Spectrum.01082-21 PMC 바로가기 [Article Type] Research Article
Pre-evaluation assessment of serological-based COVID-19 point-of-care lateral flow assays in KenyaOriginal Research Published on 2021-09-172022-10-28 Journal: African Journal of Laboratory Medicine [Category] COVID-19, [키워드] Asymptomatic authorisation board China collected coronavirus disease COVID-19 COVID-19 testing detect Emergency use IgG IgM IgM and IgG Immunity intensity Kenya lateral flow management national regulatory authority nine objective outcome Pharmacy plasma sample point-of-care point-of-care test Poison polymerase chain ranged Result reverse transcription SARS-CoV-2 sensitivity serological specificity submitted Support turn were used [DOI] 10.4102/ajlm.v10i1.1317 PMC 바로가기 [Article Type] Original Research
Sera Neutralizing Activities Against Severe Acute Respiratory Syndrome Coronavirus 2 and Multiple Variants 6 Months After Hospitalization for Coronavirus Disease 2019중증 급성 호흡기 증후군 코로나바이러스 2 및 다중 변이체에 대한 혈청 중화 활성 코로나바이러스 질병 2019로 입원 후 6개월Article Published on 2021-09-152022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 진단, 치료법, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Admission Against anti-S Anti-spike antibodies antibody B.1.1.7 B.1.351 B.1.351 variant characterized collected coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 D614G effective Efficiency Evolution experiment Hospitalized humoral Humoral response IgG IgG level IgG levels Immunoglobulin Immunoglobulin G initial intensive care unit intensive care units invasive ventilation Level marker Month Multiple neutralization Neutralizing activity neutralizing capacity neutralizing effect occur P.1 variant P.1 variants Patient patients hospitalized performed Postinfection Prospective Study quantified Quantitative respiratory SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sera serological Serological assay serological assays severe acute respiratory syndrome Coronavirus severity significantly sustained tested the patient variant with COVID-19 [DOI] 10.1093/cid/ciab308 PMC 바로가기 [Article Type] Article
Comparative Immunogenicity of BNT162b2 mRNA Vaccine with Natural SARS-CoV-2 InfectionArticle Published on 2021-09-132022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] 95%CI age anti-RBD anti-SARS-CoV-2 BNT162b2 BNT162b2 vaccine candidate vaccine clinical heterogeneity clinical trials collected Comparative Concentration COVID-19 domain effective evaluated expressing facilitate Factor females Gender HCW health care workers healthcare worker immune response immunogenicity individual Infection median mRNA natural natural infection of BNT162b2 Patient paucity of data response to vaccination Sample SARS-CoV-2 serological Side-effect Symptoms the median the RBD the spike protein vaccinated individual vaccination [DOI] 10.3390/vaccines9091017 PMC 바로가기 [Article Type] Article
Hemorrhagic and thrombotic manifestations in the central nervous system in COVID-19: A large observational study in the Brazilian Amazon with a complete autopsy seriesCOVID-19의 중추 신경계에서 출혈 및 혈전 증상 : 완전한 부검 시리즈를 가진 브라질 아마존의 대규모 관찰 연구Observational Study Published on 2021-09-102022-09-10 Journal: PLoS ONE [Category] 변종, 임상, [키워드] 95% CI absence Affect Analysis antibiotic Anticoagulant association Autopsies Autopsy Brain Brazil broad spectrum Central nervous system clinical clinical manifestations clinician CNS Comorbidities Comorbidity Complete conditions confidence interval Corticosteroid COVID-19 described diabete diabetes different clinical manifestations discharge drug events gross examination had no hemorrhage hemorrhages Hemorrhagic hemorrhagic lesion hemorrhagic lesions hemorrhaging higher risk imperative indicate individual Infection Intervention involved laboratory characteristics Lungs manifestation Manifestations Microscopy nervous system neurological neurological manifestations outcome pathology Patient patients with COVID-19 perivascular positive Prevent protocol radiologic radiological finding Rapid test Relative risk risk Risk assessment RT-PCR SARS-CoV-2 serological statistical statistical significance subarachnoid hemorrhage the disease thrombotic Thrombotic events to define treat two groups variant virus [DOI] 10.1371/journal.pone.0255950 PMC 바로가기 [Article Type] Observational Study
Soccer in the time of COVID-19: 1 year report from an Italian top league club, March 2020–February 2021COVID-19 시대의 축구: 이탈리아 최고 리그 클럽의 1년 보고서, 2020년 3월–2021년 2월From the Field Published on 2021-09-082022-09-11 Journal: Epidemiology and Infection [Category] SARS, 치료기술, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus club coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 outbreak event Football hospitalised Immunoglobulin Immunoglobulin G Italian Italy lockdown Nasopharyngeal swab nasopharyngeal swabs National Outbreaks pandemic Prevalence respiratory risk SARS-CoV-2 SARS-COV-2 infection serological Serological tests Seven sport team took place top league [DOI] 10.1017/S0950268821002065 PMC 바로가기 [Article Type] From the Field