Efficacy and safety of Lianhua Qingwen combined with conventional antiviral Western Medicine in the treatment of coronavirus disease (covid-19) in 2019 Protocol for a systematic review and meta-analysis4400 Published on 2020-07-242022-10-30 Journal: Medicine [Category] COVID-19, SARS, [키워드] addition Antiviral antiviral drug approval articles asymptomatic infection bias risk CBM center China clinical Clinical efficacy clinical trial CNKI control group Conventional coronavirus disease cough country COVID-19 crown curative database effective Efficacy and safety eligible Ethics evaluate events Evidence experiments Fever Handbook identify independent Intervention lianhua qingwen manual measure Medicine Meta-analysis Methodological quality Netherland nonrandomized Novel coronavirus outcome Pneumonia protocol regions Registration Safe searched spread to Symptoms systematic review Systemic review Traditional Chinese medicine Treatment trials VIP was used were used [DOI] 10.1097/MD.0000000000021404 PMC 바로가기 [Article Type] 4400
A systematic review and meta-analysis of the efficacy and safety of arbidol in the treatment of coronavirus disease 20194900 Published on 2020-07-242022-10-30 Journal: Medicine [Category] COVID-19, SARS, [키워드] 2019 novel coronavirus adopted adverse events Adverse reactions Analysis antiviral drug Arbidol blood sample CBM Clinical efficacy CNKI Cochrane Library contagious coronavirus disease Coronavirus disease 2019 country COVID-19 database Descriptive analysis Effect Effectiveness Efficacy and safety Epidemic evaluate Evidence fixed heterogeneity Hospitalization include Meta-analysis Novel coronavirus novel coronavirus pneumonia nucleic acid Primary outcome protocol random-effects model Registration Research severe acute respiratory syndrome coronavirus 2 spread to subgroup analysis Symptoms systematic review temperature the epidemic Treatment umifenovir VIP [DOI] 10.1097/MD.0000000000021402 PMC 바로가기 [Article Type] 4900
Quinolines-Based SARS-CoV-2 3CLpro and RdRp Inhibitors and Spike-RBD-ACE2 Inhibitor for Drug-Repurposing Against COVID-19: An in silico AnalysisMicrobiology Published on 2020-07-232022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] 3CLpro Against anti-SARS-CoV-2 therapeutics catalytic dyad China complex coronavirus COVID-19 disease docking study drug Drug repurposing functional in silico in silico analysis Infection interfere macromolecule main-protease (3CLpro) novel coronavirus SARS-CoV-2 NTP outcome oxolinic acid polymerase positive predicted quinoline based-drugs RdRP RNA-dependent RNA-polymerase SARS-CoV-2 SARS-CoV-2 RdRp seeking specific treatment spike-ACE2 complex Spread spread to suggested the WHO treat Treatment viral entry [DOI] 10.3389/fmicb.2020.01796 PMC 바로가기 [Article Type] Microbiology
Impact of self-imposed prevention measures and short-term government-imposed social distancing on mitigating and delaying a COVID-19 epidemic: A modelling study자체 예방 조치와 정부의 단기 사회적 거리두기가 COVID-19 전염병 완화 및 지연에 미치는 영향: 모델링 연구Research Article Published on 2020-07-212022-08-13 Journal: PLoS Medicine [Category] COVID-19, Medicine and Health Sciences, SARS, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Alexandra Analysis assumed attack rate Awareness best cause caused China Clinical studies Contact coronavirus coronavirus disease country COVID-19 COVID-19 epidemic demographics diagnose diagnosed diagnoses disease disease status dissemination effective Effectiveness Effects Efficacy Epidemic Epidemics epidemiological estimate evaluate Government handwashing Health policy Healthcare system Healthcare systems Height heterogeneity Impact implementation individual information initiated Intervention Isolation lifted Mask measure Mild mitigate mixing not affect Novel coronavirus outcome parameter Prevent prevented provide public health recommendation reduce reduced Reinfection researcher respiratory SARS-CoV-2 seeking severe acute respiratory syndrome Coronavirus severe disease significantly social distancing Spread spread of COVID-19 spread to stratified Stress susceptible the epidemic the timing Transmission model with COVID-19 [DOI] 10.1371/journal.pmed.1003166 PMC 바로가기 [Article Type] Research Article
Remdesivir for the Treatment of COVID-19: A Systematic Review of the LiteratureEndemic Infections Published on 2020-07-202022-10-28 Journal: Western Journal of Emergency Medicine [Category] COVID-19, MERS, SARS, [키워드] adverse events Anti-viral authors body temperature Case report clinical effectiveness clinical status clinical symptom clinical trial clinical trial registry coronavirus COVID-19 deaths defined discharged duplicate Ebola virus disease effective eligible expected global pandemic in vitro in vivo intravenous literature O2 Saturation outcome Patient patient with COVID-19 phase Remdesivir reported review SARS-CoV-2 secondary Seven shown Side effect Spread spread to systematic review treat Treatment treatment for COVID-19 Trial Vaccine was performed World Health Organization worldwide pandemic [DOI] 10.5811/westjem.2020.5.47658 PMC 바로가기 [Article Type] Endemic Infections
Physical and mental health impacts of COVID-19 on healthcare workers: a scoping reviewReview Published on 2020-07-202022-10-30 Journal: International Journal of Emergency Medicine [Category] COVID-19, [키워드] affected Anxiety article articles Care close contact collected conducted confirmed case consequence Contact cough country COVID-19 COVID-19 pandemic criteria cutaneous manifestation death Depression diagnosed disease distress eligibility Evidence Fever frontline healthcare worker Google Scholar HCW HCWs Health health impacts health-care healthcare healthcare worker Healthcare workers higher risk hygiene Impact implementation Infection infections information Insomnia Intervention intervention studies mechanism Mental mental health morbidity and mortality nasal Nurse occupational health outcome pandemic Patient patients patients with COVID-19 physical PPE Prolonged reduce Research Result risk risk factor Risk factors spread to Study design study population Support Symptom systematic literature search weakness were excluded [DOI] 10.1186/s12245-020-00299-5 PMC 바로가기 [Article Type] Review
Ivermectin: Potential Role as Repurposed Drug for COVID-19Brief Communications Published on 2020-07-192022-10-30 Journal: The Malaysian Journal of Medical Sciences : MJMS [Category] COVID-19, [키워드] 2019 novel coronavirus 2019-nCoV acute respiratory illness acute respiratory syndrome antibody antiparasitic approach being caused communicable coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 develop disease drug Drug repurposing effective effort information Ivermectin lack pandemic Pathogenesis pathway Potential proliferation rapid response Repurposed drug role SARS-CoV-2 spread to the disease therapeutic therapeutic agents therapeutic drug therapeutic option this new coronavirus Treatment Vaccine virus WHO World Health Organization [DOI] 10.21315/mjms2020.27.4.15 PMC 바로가기 [Article Type] Brief Communications
Rapid SARS-CoV-2 whole-genome sequencing and analysis for informed public health decision-making in the Netherlands Research Published on 2020-07-162022-10-05 Journal: Nature Medicine [Category] SARS, 진단, [키워드] amplification Analysis analyzed assessment Cluster Combination Community coronavirus epidemiological data Epidemiology etiology event France Germany Italy Local Netherland Netherlands outbreak Pneumonia public health Rapid reported SARS-CoV-2 SARS-CoV-2 transmission spread to These data transmission of SARS-CoV-2 virus was used Whole-genome sequence whole-genome sequencing Wuhan [DOI] 10.1038/s41591-020-0997-y [Article Type] Research
Relationship of chest CT score with clinical characteristics of 108 patients hospitalized with COVID-19 in Wuhan, ChinaResearch Published on 2020-07-142022-10-28 Journal: Respiratory Research [Category] COVID-19, [키워드] abnormal coagulation Affect affected appear association Blood C-reactive protein case sery changes in characterized Chest computed tomography Chest CT Chest CT score Clinical characteristics Clinical findings coagulation function Comorbidities COVID-19 COVID-19 infection COVID-19 patient CRP CRP level demographics determine digestive system disease erythrocyte sedimentation rate ESR examined exhibited glucocorticoid hospitalized patient Inflammation Inflammatory mediators information lung parenchyma Lungs lymphocyte objective occurred outbreak Patient patients patients hospitalized positive procalcitonin reduce reduced relationship Result retrospective sensitivity severity of COVID-19 single-center spread to systemic inflammation systemic inflammatory systemic inflammatory response therapy Tongji Hospital Tongji Medical College Treatment WBC were recorded White blood cell with COVID-19 Wuhan, China [DOI] 10.1186/s12931-020-01440-x PMC 바로가기 [Article Type] Research
Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19Review Published on 2020-07-132022-11-01 Journal: Critical Care [Category] COVID-19, [키워드] Abstract ACE2 ACE2 receptor ACE2-expressing cell acute respiratory syndrome addition angiotensin-converting enzyme 2 antibodies attenuate bind caused contribute coronavirus coronavirus disease counteract COVID-19 downregulation drugs Effect expressed global pandemic help host cell immune factor infect Infection Inflammatory Injury Local lung lung cell Multi-organ injury organ organ injury organs other organ outbreak Pathogenesis pathophysiological physiological Pneumonia RAS receptor renin-angiotensin system Restoring role SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike glycoprotein spread to Vaccines virus WHO with COVID-19 World Health Organization Wuhan, China [DOI] 10.1186/s13054-020-03120-0 PMC 바로가기 [Article Type] Review