Prioritising ‘already-scarce’ intensive care unit resources in the midst of COVID-19: a call for regional triage committees in South AfricaDebate Published on 2021-03-222022-10-28 Journal: BMC Medical Ethics [Category] Coronavirus, Fulltext, SARS, [키워드] African alleviate approach assessment clinical clinical decision clinical evidence clinician Committee COVID-19 COVID-19 pandemic COVID-19 triage criteria Critical care Critical care South Africa Critical care triage effective emotional Ethics Factor failure Governance Government health system ICU ICU care intensive care National pandemic Patient patients with COVID-19 Prioritising Prognosis rationing resource resources Scarce resources score Society South South Africa Support Triage Ventilation Volume while worsening [DOI] 10.1186/s12910-021-00596-5 PMC 바로가기 [Article Type] Debate
Successful treatment of intubation-induced severe neurogenic post-extubation dysphagia using pharyngeal electrical stimulation in a COVID-19 survivor: a case reportCase Report Published on 2021-03-222022-10-30 Journal: Journal of Medical Case Reports [Category] COVID-19, SARS, [키워드] acute respiratory syndrome aerosol-generating procedures alleviate assessment Case report contribute contributed coronavirus coronavirus disease COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 patient Critical Critically ill Critically ill patient discharge dysfunction Dysphagia electrical evaluated female FOIS full recovery health emergency help high risk ICU ICU patient Infection intake intensive care intensive care unit (ICU) International Intervention Intubated intubation Measures mechanical ventilation oral Patient patient with COVID-19 pharyngeal Pharyngeal electrical stimulation (PES) Post-extubation dysphagia (PED) reduced reflected Safe SARS-CoV-2 scale Screen shown stroke swallowing therapy tracheotomized transfer treated Treatment weakness [DOI] 10.1186/s13256-021-02763-z PMC 바로가기 [Article Type] Case Report
Puerarin enhances intestinal function in piglets infected with porcine epidemic diarrhea virusArticle Published on 2021-03-222022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] 16S rRNA activity addition Administered alanine aminotransferase alkaline phosphatase alleviate Anti-inflammatory antimicrobial agent antioxidant applied Aspartate aminotransferase Blood caecum Clostridium collected Concentration Culture determine diamine oxidase dismutase dosage Drug discovery ENhance Enterobacteriaceae Enterococcus epidemic diarrhea fatty Heat shock hydrogen peroxide Infection infectious dose inoculated interleukin-6 intestinal intestinal injury intestine lactobacillus Microbiology Molecular biology morbidity mRNA level myeloperoxidase Neutrophils nuclear PEDV peroxidase plasma plasma concentration Protein protein concentration puerarin reduced reported Result serum TCID tissue Trial tumor necrosis factor-α virus White blood cell [DOI] 10.1038/s41598-021-85880-5 PMC 바로가기 [Article Type] Article
Comparative effects of viral-transport-medium heat inactivation upon downstream SARS-CoV-2 detection in patient samples환자 샘플에서 다운스트림 SARS-CoV-2 검출에 대한 바이러스 수송 매체 열 비활성화의 비교 효과Comparative Study Published on 2021-03-182022-09-10 Journal: Journal of Medical Microbiology [Category] SARS, 진단, 치료기술, [키워드] Accuracy Affect alleviate alternatives approach arising CDC chain Chain Reaction clinically Combination Combined comparable Comparative Control correlated COVID-19 COVID-19 infection COVID-19 pandemic diagnosing diagnostic disease control downstream Effect Environmental impact evaluated extraction facilitate Healthcare provider healthcare providers heat inactivation heat-inactivation method infection control LightCycler 480 II Measures N1 and N2 National NHS outcome Patient performed polymerase chain reaction positive prevention probe protocol protocols provided purified RNA qRT-PCR qScript R 2 Rapid reaction reagent reagents reduce reducing reported required Resilience Result reverse transcription RNA extraction Roche RT-qPCR testing SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 genome SARS-CoV-2 virus sensitivity service supply chains Swab test result tested the SARS-CoV-2 virus Treatment Viral viral genomes viral inactivation viral transport media virus inactivation writing [DOI] 10.1099/jmm.0.001301 PMC 바로가기 [Article Type] Comparative Study
Combination of Angiotensin (1-7) Agonists and Convalescent Plasma as a New Strategy to Overcome Angiotensin Converting Enzyme 2 (ACE2) Inhibition for the Treatment of COVID-19Medicine Published on 2021-03-182022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] ACE2 ACE2 antibody ACE2 expression acute respiratory syndrome agonist alleviate Ang II angiotensin Angiotensin (1-7 Angiotensin 1-7 (Ang1-7) angiotensin-converting enzyme 2 antibodies appear approach ARBs AT1R binding block viral entry blocker cardiovascular pathology caused Cell circulating combination therapy concerning convalescent plasma Convalescent plasma (CP) coronavirus correlated COVID-19 COVID-19 patients detrimental effect differential expression Effect elicit expected Health infect Inflammatory response inhibition inhibitor Level lung Lung pathology modulation neutralize neutralizing capacity New pandemic pathogenesis of COVID-19 pathology pharmacological positive cells pro-fibrotic pro-inflammatory protective effect Protective effects receptor recovered patient reduced regimen risk SARS-CoV-2 Spread Strategy Symptoms therapeutic therapy Treatment upregulation viral entry viral infection virus [DOI] 10.3389/fmed.2021.620990 PMC 바로가기 [Article Type] Medicine
Knowledge of medical professionals, their practices, and their attitudes toward traditional Chinese medicine for the prevention and treatment of coronavirus disease 2019: A survey in Sichuan, ChinaResearch Article Published on 2021-03-162022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] absence affecting age alleviate Analysis app can be used China Chinese coronavirus disease COVID-19 develop drug Effectiveness Factor FIVE hospital Immunity independent information investigator knowledge media Medicine multiple logistic regression National Health Commission Neutral participant Participants Patient platform Prevent prevention of COVID-19 professional professionals remained selected Symptom TCM Traditional Treatment [DOI] 10.1371/journal.pone.0234855 PMC 바로가기 [Article Type] Research Article
Effects of home quarantine during COVID-19 lockdown on physical activity and dietary habits of adults in Saudi ArabiaArticle Published on 2021-03-152022-10-04 Journal: Scientific Reports [Category] SARS, 바이오마커, [키워드] 95% confidence interval affected alleviate Analysis Arabic between meal country COVID-19 COVID-19 pandemic dietary habit Effect English Epidemiology Google Government Health Health care home quarantine impacted lockdown male pandemic participant participated physical activity platform Prevalence Public public health quarantine response restrict Saudi Arabia significant increase significantly significantly increased Spread [DOI] 10.1038/s41598-021-85330-2 PMC 바로가기 [Article Type] Article
In silico identification of compounds from Nigella sativa seed oil as potential inhibitors of SARS-CoV-2 targetsResearch Published on 2021-03-122022-10-28 Journal: Bulletin of the National Research Centre [Category] COVID-19, [키워드] β-bisabolene 3CLpro ACE2 ADP alleviate Angiotensin-converting enzyme binding affinity characterized claimed Compound COVID-19 infection COVID-19 pandemic docking enzyme fatality highest Homo sapiens identify infected individual inhibitors of SARS-CoV-2 molecular Nigella Sativa Patient phosphatase polyprotein protease replicase reported Result RNA binding protein RNA-dependent RNA polymerase RPIA SARS-CoV-2 SARS-CoV-2 receptors selective severity target targets viral infection was performed [DOI] 10.1186/s42269-021-00517-x PMC 바로가기 [Article Type] Research
Perceived Impact of Quarantine on Loneliness, Death Obsession, and Preoccupation With God: Predictors of Increased Fear of COVID-19Psychology Published on 2021-03-102022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] alleviate association coronavirus country COVID-19 COVID-19 infections COVID-19 pandemic cross-sectional death death obsession diagnosed with COVID-19 disease existential positive psychology Factor fear Gender God God beliefs highlight identify Impact increase in Increased Intervention Isolation less lockdown loneliness measure MOST National Obsession pandemic participant Perceived Positive psychology predict predicted preoccupation promote quarantine was collected [DOI] 10.3389/fpsyg.2021.643977 PMC 바로가기 [Article Type] Psychology
Multimodality treatment in immunocompromised patients with severe COVID ‐19: the role of IL ‐6 inhibitor, intravenous immunoglobulin, and haemoperfusionCase Report Published on 2021-03-072022-10-29 Journal: Respirology Case Reports [Category] COVID-19, [키워드] administration adverse event alleviate Clinical efficacy Clinical improvement Corticosteroids COVD‐19 COVID COVID‐19 COVID‐19 infection CRS Cytokine release syndrome discharge haemoperfusion Host Immunocompromised Immunocompromised patient Inflammation Inflammatory inhibitor Intravenous immunoglobulin IVIG knowledge mechanical ventilation multimodality Multiple outcome PaO Patient profiles Research SARS‐CoV‐2 severe coronavirus disease stability survived syndrome therapeutic Therapies therapy Tocilizumab treated Treatment [DOI] 10.1002/rcr2.733 PMC 바로가기 [Article Type] Case Report