Controlled trial – Page 29 – Communicable Diseases Research

Effectiveness of extracorporeal blood purification (hemoadsorption) in patients with severe coronavirus disease 2019 (COVID-19)

중증 코로나바이러스감염증-19(COVID-19) 환자의 체외 혈액 정화(혈액흡착) 효과

Research Article

Published on 2020-08-202022-08-13
Journal: BMC Nephrology [Category] MERS, 임상,

Pakistan Randomized and Observational Trial to Evaluate Coronavirus Treatment (PROTECT) of Hydroxychloroquine, Oseltamivir and Azithromycin to treat newly diagnosed patients with COVID-19 infection who have no comorbidities like diabetes mellitus: A structured summary of a study protocol for a randomized controlled trial

당뇨병과 같은 동반 질환이 없는 새로 진단된 COVID-19 감염 환자를 치료하기 위한 Hydroxychloroquine, Oseltamivir 및 Azithromycin의 코로나바이러스 치료(PROTECT) 평가를 위한 파키스탄 무작위 및 관찰 시험: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2020-08-082022-08-13
Journal: Trials [Category] MERS, 임상,

[키워드] 1:1 adaptive age allocation sequence approval authority Azithromycin baseline bioethics blinded Blinding board clinical Clinical improvement clinical status Cohort cohort study Combination combinations Committee Comorbidity comparator computer-generated Controlled trial coronavirus COVID-19 diabete diabetes Diabetes Mellitus diagnosed disease dissemination distress drug dyspneic Effectiveness eight element evaluate excluded expected Final flexibility Follow-up followed by Formal Gender groups Hospitalized Hydroxychloroquine hypertension Infection intervention group kidney Kidney failure lactating liver medical condition monotherapy multi-center multicenter nasal swab nucleic acid number objective observation open open label Ordinal Scale oseltamivir parameter participant patients patients with COVID-19 PCR positive pregnant Primary outcome Primary outcomes protocol public health qRT-PCR random randomization Randomized Randomized controlled trial randomized study recruited recruitment regimen Registered Registration reported respiratory distress Safety Sample size Self-isolation Seven seven-category ordinal scale Standard status Study protocol subject subsequent sulfate test negative tested three groups treat Treatment Trial twice a day Version virus website
[DOI] 10.1186/s13063-020-04616-4 PMC 바로가기 [Article Type] Letter

COVID-19 in the operating room: a review of evolving safety protocols

Review

Published on 2020-07-202022-10-28
Journal: Patient Safety in Surgery [Category] COVID-19,

Breath Regulation and yogic Exercise An online Therapy for calm and Happiness (BREATH) for frontline hospital and long-term care home staff managing the COVID-19 pandemic: A structured summary of a study protocol for a feasibility study for a randomised controlled trial

호흡 조절 및 요가 운동 COVID-19 대유행을 관리하는 최전선 병원 및 장기 요양원 직원을 위한 평온과 행복을 위한 온라인 치료(BREATH): 무작위 대조 시험에 대한 타당성 연구를 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2020-07-142022-08-13
Journal: Trials [Category] SARS, 임상,

[키워드] 1:1 active treatment All study participant All study participants allocation concealment Analysis Anxiety ARMS blinded Blinding breath breaths Canada Care collected Complete Completeness completion consent form control arm Controlled trial COVID-19 COVID-19 pandemic COVID-19 patient data entry Depression determine dissemination element eligibility English enhancement exercise feasibility feasible foundation Group allocation Health Health promotion Healthcare staff healthcare worker Healthcare workers healthy hospital IMPROVE include Insomnia interactive module Intervention involved London Long-term care management measure medium mental health mind-body intervention mindfulness Mindfulness-based muscle relaxation music therapy number objective offered online session Open-label outcome participant phase Phase I physical Prevent Program progressive muscle relaxation promotion protocol Psychoeducation randomised randomised controlled trial randomization randomize Randomized Randomized controlled trial RCT recruited recruitment REDCap reduce Research researcher Resilience resiliency retention Sample size scheduling significantly status study hypothese study hypotheses Study protocol subsequent supervision therapy Treatment Trial USA website Weekly windows Work stress yoga
[DOI] 10.1186/s13063-020-04583-w PMC 바로가기 [Article Type] Letter

The efficacy of acupuncture for improving the side effects of COVID-19 western medicine treatments A protocol for a systematic review and meta-analysis

3800

Published on 2020-07-102022-10-30
Journal: Medicine [Category] COVID-19, SARS,

[키워드] activated acupuncture adverse effects adverse event age alanine aminotransferase Aspartate aminotransferase blood pressure C-reactive protein CBM Chinese clinical observation clinical symptom Clinical symptoms CNKI Cochrane Library Controlled trial Coronavirus disease 2019 cough COVID-19 CRP database diagnosed with COVID-19 diarrhea disease stage Effectiveness Efficacy evaluate Evidence fatigue Fever Follow-up Handbook high mortality identify immune regulation include Infrastructure kidney literature liver liver enzyme medication Meta-analysis mortality rate myalgia nausea neuroendocrine outcome pandemic Patient patients with COVID-19 physical problems PROSPERO database protocol randomization receiving respiratory infectious disease review searched secondary serum cytokine levels Sex Side effect skin rash systematic review treat Treatment used to evaluate vomiting Western medicine
[DOI] 10.1097/MD.0000000000021185 PMC 바로가기 [Article Type] 3800

Azithromycin added to hydroxychloroquine for patients admitted to intensive care due to coronavirus disease 2019 (COVID-19)—protocol of randomised controlled trial AZIQUINE-ICU

Study Protocol

Published on 2020-07-082022-10-29
Journal: Trials [Category] COVID-19, SARS,

[키워드] added addition Administered Admission allergy Azithromycin benefit clinical cohort of patient Combination Controlled trial coronavirus disease coronavirus SARS-CoV-2 COVID-19 COVID-19 infection criteria Deterioration disease dose double-blind drug early administration Efficacy febrile disease groups hospital Hydroxychloroquine hypothesise ICU ICU admission in vitro include Infection intensive care intubation limit limitation lung mechanical ventilation mechanically ventilated Mortality not differ novel Novel coronavirus outcome outcomes pathway Patient patients Placebo Pregnancy Prevent prevented progressive COVID-19 Prospective randomised randomised controlled trial RCT receive Respiratory failure SARS-CoV-2 secondary severe COVID-19 Standard of care survival susceptible Symptom Treatment Trial viral replication
[DOI] 10.1186/s13063-020-04566-x PMC 바로가기 [Article Type] Study Protocol

Acupuncture for breathlessness in COVID-19 A protocol for systematic review and meta-analysis

3800

Published on 2020-07-022022-10-30
Journal: Medicine [Category] COVID-19, SARS,

Randomised controlled trial comparing efficacy and safety of high versus low Low-Molecular Weight Heparin dosages in hospitalized patients with severe COVID-19 pneumonia and coagulopathy not requiring invasive mechanical ventilation (COVID-19 HD): a structured summary of a study protocol

Letter

Published on 2020-06-262022-10-29
Journal: Trials [Category] Coronavirus, SARS,

[키워드] 1:1 24 hour Administered airway allocation concealment Alpha ambient analysed aneurysms Anticoagulant treatment anticoagulation antiplatelet Arm arterial assigned Atrial fibrillation bleeding bleeding event block size Blood BMI Body Breastfeeding breath calculated Cancer clinical clinically Coagulopathy Concomitant conjunctival Continuous contributed Control control group Controlled trial corpus COVID-19 COVID19 criteria Critical D-dimer D-dimer level Day death defined detect diagnostic discharged disease severity dissemination dosage dose effective Efficacy and safety element enoxaparin Epistaxis EudraCT event events expected fibrinogen level gingival bleeding group Haemoglobin haemoptysis health-care hematemesis hematoma hemodynamic heparin High dose high risk history hospital discharge Hospital stay hospitalized patient hypersensitivity Hypothesis IL-6 Impaired impairing improvement IMV In-hospital indication initiated Inpatient INR internal Intervention intervention group Intra-articular intramuscular invasive Invasive mechanical ventilation involved Italian Italy laboratory parameter LMWH low dose low-molecular weight heparin macroscopic Major major bleeding management Mechanical mechanical ventilation medical intervention Medicine Modena NIV Non-invasive number objective occur Occurrence open label ophthalmic oral anticoagulant outcome oxygen paO2/fiO2 parallel group participant pathology Patient performed Pharyngeal swab plasma Platelet Pneumonia positive pregnancy test Presence pressure Primary outcome prophylactic dose prosthetic protocol random randomisation randomised randomised controlled randomised controlled trial randomization Rate receiving recorded recruited Rectal Bleeding reduce reduction in Registered renal function reported required respiratory risk risk of death Sample size SARS-CoV-2 secondary secure Severe COVID-19 pneumonia severe disease significantly Spontaneous standard oxygen therapy Stata status stratified stroke study drug Study protocol subcutaneously surgical susceptible symptomatic syndrome therapeutic dose therapy thrombocytopenia time transfusion Treatment unfractionated heparin unit Vascular venipuncture Venous Thromboembolism web-based system website weight Withdrawal worsening
[DOI] 10.1186/s13063-020-04475-z PMC 바로가기 [Article Type] Letter

A prospective, randomized, controlled study assessing vagus nerve stimulation using the gammaCore®-Sapphire device for patients with moderate to severe CoViD-19 Respiratory Symptoms (SAVIOR): A structured summary of a study protocol for a randomised controlled trial”

Letter

Published on 2020-06-262022-10-29
Journal: Trials [Category] Coronavirus, SARS,

[키워드] 1:1 Acute respiratory failure Administered Admission Adverse age Aneurysm Antibiotics atherosclerotic baseline blind blood pressure Brain cardiovascular disease carotid cerebrovascular accident cervical spine chronic clinical trial Complete congestive heart failure Consent control group Controlled trial Coronary artery disease cough COVID-19 criteria current cytokine Cytokine storm Day decrease Delay Disabled disease dissemination distress dose electrical element eligible enrolled evaluate expected Follow-up Gender growth Healthcare provider hemorrhage history hospital hospital discharge ICU admission Informed Initiation interleukin interleukin 6 Intervention less mechanical ventilation mechanical ventilator Mild moderate Mortality Myocardial infarction nerve stimulation number O2 Saturation objective occur Older open label outcome oxygen Oxygen level Oxygen therapy parallel group participant Patient patients with moderate per day persist positive prophylactically protocol pulmonary randomisation randomised randomised controlled randomised controlled trial randomization Randomized recruited recruitment reduce reduction regimen Registered required Research respiratory Respiratory failure Sample size Sapphire saturation second dose secondary severity Shortness of breath SOC Spain Standard Standard of care status storm stratified study group Study protocol subject supplemental oxygen supplemental oxygen requirement tested trauma Treatment tumor necrosis factor tumors uncontrolled Vague neurostimulation Valencia Ventilation ventilatory support website women
[DOI] 10.1186/s13063-020-04486-w PMC 바로가기 [Article Type] Letter

Chinese medicine for COVID-19 A protocol for systematic review and meta-analysis

3800

Published on 2020-06-192022-10-30
Journal: Medicine [Category] COVID-19, SARS,

[키워드] 95% CIs 95% confidence interval adverse effect Analysis appear article Asia asymptomatic infection cause CBM Chest CT China Chinese Chinese medicine CIs CNKI Cochrane Library Consensus continuous variable Controlled trial Coronavirus disease 2019 COVID-19 database death disagreement disease East Efficacy Efficacy and safety Evidence Handbook hospitalised include Infrastructure journal literature mean difference Meta-analysis Mild Novel coronavirus Nucleic acid detection Odds ratio outbreak outcome participant Patient performed Placebo Pneumonia protocol recruited reported resolved Respiratory disease Respiratory failure Respiratory illness Respiratory samples Result review risk risk of bia Risk of bias SARS-COV-2 infection Science searched severe viral pneumonia Spread systematic review technique therapeutic agents treat Treatment upper respiratory tract variable VIP virus with COVID-19 Wuhan, China
[DOI] 10.1097/MD.0000000000020660 PMC 바로가기 [Article Type] 3800