Investigation of 100 SARS-CoV-2 infected families in Wuhan: Transmission patterns and follow-upResearch Theme 7: Rapid Reviews on COVID-19 Evidence Published on 2020-12-232022-10-31 Journal: Journal of Global Health [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome baseline characteristics close contact Community confirmed case confirmed cases Contact coronavirus died discharged eight enrolled evaluate evaluated family Follow-up follow-up period hospital Hospitalization hospitals Infection investigation Isolation Mild moderate nucleic acid test number of infected occurred outcome outcomes Participants Patient positive positive test result Prevent quarantine reported Result returned SARS-CoV-2 SARS-COV-2 infection Severe case Spread Transmission transmission pattern transmission patterns treated were infected Wuhan [DOI] 10.7189/jogh.10.021103 PMC 바로가기 [Article Type] Research Theme 7: Rapid Reviews on COVID-19 Evidence
Natural Selection Plays an Important Role in Shaping the Codon Usage of Structural Genes of the Viruses Belonging to the Coronaviridae FamilyArticle Published on 2020-12-222022-10-28 Journal: Viruses [Category] COVID-19, [키워드] adopted Analysis analyzed base Belonging Cell codon codon usage Codon usage bias comprehensive analysis Coronaviridae demonstrated ENCODE Evolution Factor family Genes Genetic Genome Host mutational selection natural natural selection neutrality parity poly-A tail Replication responsible RNA role Selection shaping single-stranded positive-sense survival synonymous the Coronaviridae Usage virus [DOI] 10.3390/v13010003 PMC 바로가기 [Article Type] Article
SARS-CoV-2 pandemia in Lombardy: the impact on family Paediatricians롬바르디아의 SARS-CoV-2 대유행: 가족 소아과 의사에게 미치는 영향Letter to the Editor Published on 2020-12-212022-09-10 Journal: Italian Journal of Pediatrics [Category] MERS, SARS, 진단, 치료기술, [키워드] addition Adults affected antibody Care children clinics close contact coronavirus COVID-19 COVID-19 pandemic detect exposure to family Family paediatricians General population HCWs Health care Health care worker health care workers Hospitalization IgG antibodies IgG antibody increased risk individual individuals initiative Italian lombardy Medici Pandemia pediatric Prevalence provided raising Rapid test Rapid tests reported SARS-CoV-2 SARS-CoV-2 antibodies spreading study participant Study participants subject Symptom Symptoms tested the disease [DOI] 10.1186/s13052-020-00950-0 PMC 바로가기 [Article Type] Letter to the Editor
The Short- and Long-Range RNA-RNA Interactome of SARS-CoV-2SARS-CoV-2의 단거리 및 장거리 RNA-RNA 상호작용체Article Published on 2020-12-172022-09-10 Journal: Molecular Cell [Category] MERS, SARS, 유전자 메커니즘, [키워드] Antiviral strategies arch base bases Bearing Cell cells Comprehensive COMRADES conserved Coronaviridae coronavirus COVID-19 COVID-19 pandemic dependent on develop discontinuous transcription distal effort elements engage etiologic agent family FSE-arch full-length SARS-CoV-2 genome Host host-virus include Interaction interactome mapped mechanism MERS-CoV Multiple network nucleotides Pathways regulate Replication resulting ribosomal frameshifting RNA RNA structure RNA virus RNA-RNA interaction RNA-RNA interactions RNAs SARS-CoV-2 SARS-CoV-2 genome single-stranded RNA genome single-stranded RNA genomes Structure subgenomic mRNAs the SARS-CoV-2 genome topologies Topology translation Viral viral genome viral transcription virus virus RNA viruses [DOI] 10.1016/j.molcel.2020.11.004 PMC 바로가기 [Article Type] Article
Hierarchical Modelling of COVID-19 Death Risk in India in the Early Phase of the PandemicSpecial Issue Article Published on 2020-12-152022-11-01 Journal: The European Journal of Development Research [Category] COVID-19, [키워드] Bayesian model build census conditions COVID-19 Data combining death epidemic modelling Factors family Health Hierarchical Hierarchical model IMPROVE India Latent variable morbidity obesity Older outcome pandemic phase Policy populations risk SARS-CoV2 virus pandemic severe COVID-19 supplementary material survey the epidemic Transmission World Health Organisation [DOI] 10.1057/s41287-020-00333-5 PMC 바로가기 [Article Type] Special Issue Article
Opportunity for change: Undergraduate training in family medicineOpen Forum Published on 2020-12-112022-10-29 Journal: South African Family Practice [Category] Coronavirus, MERS, SARS, [키워드] assessment Bachelor change changed Continuous coronavirus disease COVID-19 curriculum Department family Family medicine introduced maintain MBChB medical education Medicine Modification opportunity pandemic provided surgery university [DOI] 10.4102/safp.v62i1.5225 PMC 바로가기 [Article Type] Open Forum
COVID-19 and Palliative Care Services: Comparative Patterns of Inpatient, Outpatient, and Consultation Services in a Tertiary Care Center in RiyadhPain Management Published on 2020-12-092022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome affecting applied Care caused center city Comparative conducted consultation coronavirus coronavirus disease Coronavirus disease 2019 (COVID-19) country COVID-19 COVID-19 outbreak COVID-19 pandemic death discharged home Epidemic examined family healthcare worker highly pathogenic hospital hospitals impact on service initial Inpatient King outbreak Outpatient palliative palliative and supportive care Palliative care pandemic Patient pattern positive COVID-19 PPS Practice patterns Precaution protocols provided Result Retrospective study SARS-CoV-2 sars-cov-2 (severe acute respiratory syndrome coronavirus -2) Saudi Arabia service Tertiary World Health Organization [DOI] 10.7759/cureus.11996 PMC 바로가기 [Article Type] Pain Management
Syncytia formation by SARS-CoV-2-infected cellsSARS-CoV-2에 감염된 세포에 의한 융합체 형성Article Published on 2020-12-012022-09-11 Journal: The EMBO Journal [Category] MERS, SARS, 바이오마커, 유전자 메커니즘, 진단, [키워드] ACE2 Antiviral effect cellular cellular mechanism contrary COVID-19 Effect ENhance Express extensive lung damage facilitate family FUSE fusion IFITM1 IFITM2 IFITM3 IFITMs increase infected cells inhibit interferon lung damage modulated neighboring cells Pneumocytes Protein restriction factor SARS-CoV-2 SARS-CoV-2-infected cell SARS-CoV-2-infected cells Serine serine protease severe cases Spike protein Syncytia syncytia formation the Spike TMPRSS2 transmembrane protein Trigger triggers Viral Viral protein Viral proteins virions viruses [DOI] 10.15252/embj.2020106267 PMC 바로가기 [Article Type] Article
Hydroxychloroquine for prophylaxis of COVID-19 physicians survey: Despite lack of evidence, many would take or give to dear ones, and despite the perceived necessity of an RCT, few would participate코로나19 예방을 위한 하이드록시클로로퀸 내과의사 설문조사: 근거 부족에도 불구하고 많은 사람이 소중한 사람에게 받거나 주고, RCT의 필요성 인식에도 불구하고 소수 참여Article Published on 2020-12-012022-09-11 Journal: Journal of Evaluation in Clinical Practice [Category] 치료제, [키워드] administer age asked belief Care collected concerning Controlled trial correlation COVID-19 COVID-19 patients Evidence Facebook family Hydroxychloroquine indicated information involved lack opinion patients performed physician Physicians prophylactically Prophylaxis questionnaire Randomized randomized clinical trial Randomized controlled trial RCT survey thought Treatment treatment for COVID-19 treatment regimen Trial use of hydroxychloroquine [DOI] 10.1111/jep.13484 PMC 바로가기 [Article Type] Article
Persisting Neutralizing Activity to SARS-CoV-2 over Months in Sera of COVID-19 PatientsCOVID-19 환자의 혈청에서 수개월 동안 SARS-CoV-2에 대한 중화 활성 지속Article Published on 2020-11-272022-09-01 Journal: Viruses [Category] SARS, 진단, 치료법, [키워드] activity anti-SARS-CoV-2 antibodies applied association Blood Clinical course clinical disease Course COVID-19 COVID-19 patients declined disease onset dropped elevated family IgA IgA level IgG antibodies IgG antibody IgG level IgG levels immune response Immunity Mild Month N-protein NAbs nasopharyngeal Neutralizing activity observation period parameter Patient peaked plateau reached SARS-CoV-2 SARS-CoV-2 N-protein SARS-CoV-2 neutralizing activity SARS-CoV-2 RT-qPCR SARS-CoV-2 S1-RDB protein serological virus load Virus neutralization [DOI] 10.3390/v12121357 PMC 바로가기 [Article Type] Article