Outbreak of Central American born Shigella sonnei in two youth camps in Belgium in the summer of 20192019년 여름 벨기에의 두 청소년 캠프에서 발생한 중앙아메리카 출신 시겔라 소네이의 발생Brief Report Published on 2021-02-112024-08-21 Journal: European Journal of Clinical Microbiology & Infectious Diseases [Category] 세균성이질, [키워드] Cluster analyses Next-generation sequencing outbreak Shigella sonnei [DOI] 10.1007/s10096-021-04164-y PMC 바로가기 [Article Type] Brief Report
Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resourcesArticle Published on 2021-02-092022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, [키워드] ACE2 affected Agricultural genetics Animal breeding ANPEP Asian component Coronavirus infection Data mining described Describing Diseases DPP4 European example Genetic Genetic markers Genomics Host host gene host receptor Infection Infectious diseases investigated involved mechanisms Mild Next-generation sequencing one health Perspective Population Population genetics populations protein sequence proteinase reservoir resource resources risk TMPRSS2 Variability variant viral infections viral spike protein [DOI] 10.1038/s41598-021-82956-0 PMC 바로가기 [Article Type] Article
Structural aspects of lesional and non-lesional skin microbiota reveal key community changes in leprosy patients from India레프리 환자에서 병변 피부 미생물군과 비병변 피부 미생물군의 구조적 측면은 인도 환자에서 주요 군집 변화를 드러낸다.Article Published on 2021-02-082024-07-29 Journal: Burma Med J [Category] 한센병, [키워드] Data processing DNA sequencing Microbial communities Next-generation sequencing skin diseases [DOI] 10.1038/s41598-020-80533-5 PMC 바로가기 [Article Type] Article
Proteo-Genomic Analysis of SARS-CoV-2: A Clinical Landscape of Single-Nucleotide Polymorphisms, COVID-19 Proteome, and Host ResponsesArticle Published on 2021-02-082023-06-15 Journal: Journal of Proteome Research [Category] MERS, SARS, [키워드] COVID-19 COVID-19 proteomics Genomics host proteome mass spectrometry Next-generation sequencing SARS-CoV-2 [DOI] 10.1021/acs.jproteome.0c00808 PMC 바로가기 [Article Type] Article
Molecular characterization and the mutation pattern of SARS-CoV-2 during first and second wave outbreaks in Hiroshima, Japan일본 히로시마에서 1차 및 2차 유행 중 SARS-CoV-2의 분자 특성 및 돌연변이 패턴Research Article Published on 2021-02-052022-08-13 Journal: PLoS ONE [Category] MERS, 변종, 유전자 메커니즘, [키워드] addition Amino acid amino acid change amino acid changes Analysis Asian base substitution cause Control D614G variant D614G variants defect European examined First wave GenBank GISAID Hiroshima indicated insertion Japan local outbreak local outbreaks molecular Mutation mutation rate mutations nasal swab nested PCR Next-generation sequencing nucleotide occurred ORF1a ORF1b ORF8 ORF8 protein outbreak PCR performed Phylogenetic tree predominant Primers ranged Result retrieved RT-qPCR SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 strains second wave sequence Seven single-nucleotide strain Strains undetectable Viral Viral load [DOI] 10.1371/journal.pone.0246383 PMC 바로가기 [Article Type] Research Article
Saliva is more sensitive than nasopharyngeal or nasal swabs for diagnosis of asymptomatic and mild COVID-19 infection타액은 무증상 및 경증 COVID-19 감염 진단을 위해 비인두 또는 비강 면봉보다 더 민감합니다.Article Published on 2021-02-042022-09-01 Journal: Scientific Reports [Category] MERS, 진단, 치료기술, 치료법, [키워드] Acute respiratory infection Analysis Asymptomatic B.6 Care circulating collected Community community care confirmed case correlation COVID-19 diagnosis COVID-19 infection COVID-19 testing Ct values cycle cycle threshold Diagnosis diagnosis of COVID-19 Infection Isolation large cohort Lineage migrant workers Mild nasal nasal swab nasopharyngeal Next-generation sequencing NGS phylogenetic analyses Phylogenetic analysis positive recruited respiratory RT-PCR Saliva SARS-CoV-2 sensitivity Singapore subject subjects Swab swabs tested threshold utility Viral viral genome viral genome coverage viral infection was done [DOI] 10.1038/s41598-021-82787-z PMC 바로가기 [Article Type] Article
Essential interpretations of bioinformatics in COVID-19 pandemicReview article Published on 2021-02-012022-10-05 Journal: Meta Gene [Category] 신약개발, 유전자 메커니즘, [키워드] analyzed applied bioinformatics candidate computer-aided drug design COVID-19 COVID-19 pandemic COVID-19 research drug candidate drug design Essential Genetic Genetic variations Genome wide association study Genome-wide association studies global pandemic implementation in silico in viral information Interpretation methodology next generation sequencing Next-generation sequencing pathogen produced public health Research SARS-CoV-2 SARS-CoV-2 viral Scientific community sequenced sequencing errors the SARS-CoV-2 genome unique Vaccine development [DOI] 10.1016/j.mgene.2020.100844 [Article Type] Review article
Detection of SARS-CoV-2 from patient fecal samples by whole genome sequencingResearch Published on 2021-01-302022-11-01 Journal: Gut Pathogens [Category] COVID-19, [키워드] Analysis Complete Concordance coronavirus COVID-19 COVID-19 patients detection Fecal sample fecal samples Fecal–oral transmission Fecal–oral transmission highlight identify methodology Mutation nasopharyngeal Next-generation sequencing NGS participant Patient patients Result RT-PCR RT-PCR nasopharyngeal swab SARS-CoV-2 SARS-CoV-2 detection Sequencing Stool variant Variation viability whole genome [DOI] 10.1186/s13099-021-00398-5 PMC 바로가기 [Article Type] Research
SequencErr: measuring and suppressing sequencer errors in next-generation sequencing dataResearch Published on 2021-01-252022-11-01 Journal: Genome Biology [Category] COVID-19, [키워드] Accuracy Analysis can be used cellular computational method country Critical dataset datasets DNA DNA library DNA sequencing elevated error rate Error suppression FastQC flow cell Genetic heterogeneous IMPROVE Lighter MONITOR Musket Next-generation sequencing occur outlier overlapping populations Quality control reduced Region Research Result reveal Sequencer/instrument error Sequencing suppress [DOI] 10.1186/s13059-020-02254-2 PMC 바로가기 [Article Type] Research
Differential expression and correlation analysis of miRNA–mRNA profiles in swine testicular cells infected with porcine epidemic diarrhea virusArticle Published on 2021-01-212022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] Analysis bacterial invasion Bioinformatics analysis Cell Cell Biology Cellular signalling networks Computational biology and bioinformatics Control correlated correlation Correlation analysis Cytoscape DE miRNA DE miRNAs DESeq differential expression differentially expressed epidemic diarrhea Epigenetic epithelial cells expression expression pattern Gene regulatory networks group groups High-throughput screening Host immune response Immunity in vitro induce Infection Interaction involved mechanism Mechanisms of disease microRNA miRanda miRNA miRNA expression mRNA mRNAs Next-generation sequencing NF-κB signaling NGS Pathogenesis pathway PEDV performed polymerase chain predicted profile qRT-PCR Quantitative R package Randomly reverse transcription selected sequencing data Strains variant viral pathogenicity virulent virus [DOI] 10.1038/s41598-021-81189-5 PMC 바로가기 [Article Type] Article