Piloting an integrated SARS-CoV-2 testing and data system for outbreak containment among college students: A prospective cohort studyResearch Article Published on 2021-01-262022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] adaptive Administered approach average Campus Cohort college conducted Contact tracing contribute country COVID-19 testing COVID-19 transmission data-driven database develop effective enrolled Guidance higher risk Infection information outbreak PCR test PCR-positive positive prospective cohort study reduction reported symptoms SARS-CoV-2 testing selected Surveillance Symptom synergy target tested Testing Trigger uptake [DOI] 10.1371/journal.pone.0245765 PMC 바로가기 [Article Type] Research Article
Analysis of COVID-19-Related RT-qPCR Test Results in Hungary: Epidemiology, Diagnostics, and Clinical OutcomeMedicine Published on 2021-01-262022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] age and sex clinical conducted Coronavirus infection Coronavirus infections COVID-19 COVID-19 case diagnose disease E-gene epidemiological Epidemiology first test first-wave Hungary ICU admission immunologically IMPROVE in-hospital mortality Infection initially asymptomatic patient intensive care Mortality naïve no difference outcome pandemic patients PCR diagnostics PCR positivity PCR test performed positive required Result Retrospective analysis RT-qPCR RT-qPCR test SARS-CoV-2 statistical analysis Surveillance survived Test tested Testing [DOI] 10.3389/fmed.2020.625673 PMC 바로가기 [Article Type] Medicine
Thermovaccination – thermoheliox as a stimulator of the immune response. Kinetics of the synthesis of antibodies and C-reactive protein in coronavirus infectionThermovaccination - 면역 반응의 자극제로서의 열일광. 코로나바이러스 감염에서 항체 및 C 반응성 단백질 합성의 동역학Clinical Trial Published on 2021-01-252022-09-12 Journal: Chemico-biological interactions [Category] MERS, SARS, 임상, 진단, [키워드] acute phase analyzed antibody Blood C-reactive protein changes in clinical Concentration conducted coronavirus Coronavirus infection disease Dynamics Efficiency immune response Immunoglobulin Immunoglobulin G infected patient kinetic Kinetic model Kinetics organism oxygen PCR test PCR-Test shown Thermoheliox. Treatment Trial virus [DOI] 10.1016/j.cbi.2020.109339 PMC 바로가기 [Article Type] Clinical Trial
Evaluation of two rapid antigen tests to detect SARS-CoV-2 in a hospital setting병원 환경에서 SARS-CoV-2를 검출하기 위한 두 가지 빠른 항원 검사 평가Original Investigation Published on 2021-01-162022-09-10 Journal: Medical Microbiology and Immunology [Category] MERS, 진단, 치료기술, [키워드] acute infection acute infections alternative Antigen assays Asymptomatic clinical sensitivity complement Containment strategy COVID-19 COVID-19 point-of-care detect Diagnosis diagnostic diagnostic sensitivities diagnostic test Efficacy emergency rooms evaluated false false-negative False-positive Germany Health care Health care worker health care workers hospital implementation independent infected individuals International Munich National outcome pandemic Patient care PCR assay PCR assays PCR test PCR tests PCR-negative PCR-positive POCT primary diagnosis question Rapid rapid antigen test respiratory SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigen test SARS-CoV-2 pandemic SARS-CoV-2-infected individuals sensitivity specificity Support Swab symptomatic individuals symptomatic patient Test test results the SARS-CoV-2 time-consuming university utility widespread [DOI] 10.1007/s00430-020-00698-8 PMC 바로가기 [Article Type] Original Investigation
Case Report: The Coronavirus Disease 2019 (COVID-19) Pneumonia With Multiple ThromboembolismNeurology Published on 2021-01-122022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] acute respiratory syndrome anti-inflammatory treatment Anticoagulant treatment Blood coagulation chest pain clinician coronavirus coronavirus disease COVID-19 demonstrated diagnosed diagnostic value discharged DVT Dyspnea effective Fever Hemorrhagic highlight home quarantine illness onset Infarction infected with COVID-19 laboratory result limb Multiple multiple thromboembolism myalgia occur oxygen supply Patient PCR PCR test Pneumonia polymerase chain presenting Prevalence pulmonary damage remained reported SARS-CoV-2 SARS-CoV-2 virus Severe COVID-19 pneumonia Spread Symptoms tested the patient therapy throat swab Thromboembolism thrombosis thrombotic event Treatment weakness Wuhan, China [DOI] 10.3389/fneur.2020.625272 PMC 바로가기 [Article Type] Neurology
Hydroxychloroquine in the treatment of adult patients with Covid-19 infection in a primary care setting (LIBERTY): A structured summary of a study protocol for a randomised controlled trial일차 진료 환경(LIBERTY)에서 Covid-19 감염 성인 환자 치료에 사용되는 하이드록시클로로퀸: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-01-112022-09-10 Journal: Trials [Category] MERS, 임상, [키워드] 1:1 addition addressed administration Adult patients adverse event adverse events AEs age all-cause hospitalization Antibody Response Anxiety Anxiety Disorder ARMS association Biomarker blinded Blinding Blood BMI capture Care changes changes in Characteristics clinical trial concentrations concomitant medications conducted Contact Course COVID-19 COVID-19 infection COVID-19-related symptoms criteria death deleting Demographic variables diabetes Diabetes Mellitus disease dissemination double-blind Effect element enrolment enzyme EudraCT evaluate exclusion expected exploratory exploratory endpoint Exploratory endpoints female Formulation GAD-7 Generalized Generalized Anxiety Disorder Genetic variation HCQ Health care HLA haplotypes hospital Hospitalization hospitalizations Hydroxychloroquine Hypothesis identify include Inclusion independent individual Infection information intensive care unit lactation masking mental health Meta-analysis Mortality Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples number number of deaths objective onset of symptom open care outcome Outpatient outpatients parallel-group participant Patient patient data PCR test PCR testing PCR-confirmed Placebo placebo-controlled post-hoc predict Pregnancy presenting primary care primary endpoint protocol public health public health care randomised randomised controlled trial randomization list Randomized Randomly receive recruitment reduce Registered Regulation repeated reported respiratory respiratory distress respiratory rate response risk room air SAEs Sample size SARS-CoV-2 SARS-CoV-2 PCR test SARS-CoV-2 viral shedding Satakunta secondary endpoint Secondary endpoints Secondary objectives serious AE serum Seven severe pneumonia severity specific treatment status study participant Study participants study population Study protocol subgroup analysis subject supplementary material Suspected Symptom Symptoms technology test result therapeutic potential Tolerability treated Treatment treatment allocation treatment arm Trial Trial registration twice a day type 1 or type 2 Uppsala variable Viral was performed website Well-being [DOI] 10.1186/s13063-020-04989-6 PMC 바로가기 [Article Type] Letter
SARS-CoV-2 RT-PCR profile in 298 Indian COVID-19 patients: a retrospective observational studyObservational Study Published on 2021-01-092022-10-05 Journal: Pathogens and disease [Category] 임상, [키워드] age average collected Comorbidities conducted COVID COVID-19 COVID-19 patients different time points Elderly patient eligible enrolment first positive hospital knowledge Laboratory majority male nasopharyngeal New nucleic acid oropharyngeal swabs pandemic Patient PCR positivity PCR test performed positive RT-PCR Positive test positive test result profile profile. retrieved retrospective RT-PCR SARS CoV-2 SARS-CoV-2 SARS-CoV-2 RT-PCR statistically significant symptom onset symptomatic patient Treatment viral dynamics were excluded [DOI] 10.1093/femspd/ftaa064 PMC 바로가기 [Article Type] Observational Study
COVID-19 as the cause of thrombosis: recognising COVID-19 infection in apparently asymptomatic patients혈전증의 원인인 코로나19: 무증상 환자에서도 코로나19 감염 인지Case Reports Published on 2021-01-072022-09-11 Journal: BMJ case reports [Category] 치료기술, [키워드] abdominal pain asymptomatic patient Case report clinician COVID-19 COVID-19 infection Critically ill critically ill patients CT scan develop disease emergency department emergency medicine Evidence evidence of Factor hypercoagulable manifestation mild respiratory no risk Pain Patient PCR test presenting presenting symptom pulmonary renal respiratory Respiratory failure respiratory symptom respiratory symptoms Risk factors secondary to subsequent Symptom the patient thrombosis thrombotic thrombotic complication Thrombotic complications thrombotic event Thrombus treat [DOI] 10.1136/bcr-2020-241027 PMC 바로가기 [Article Type] Case Reports
Efficacy and safety of nitazoxanide plus atazanavir/ritonavir for the treatment of moderate to severe COVID-19 (NACOVID): A structured summary of a study protocol for a randomised controlled trial중등도에서 중증의 COVID-19(NACOVID) 치료를 위한 nitazoxanide + atazanavir/ritonavir의 효능 및 안전성: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Comparative Study Published on 2021-01-042022-09-10 Journal: Trials [Category] 신약개발, 임상, 치료제, [키워드] 1:1 24 hour 24 hours achievement addition Administered African age allocation anticipated antiretroviral drugs antiviral activity approval Atazanavir atazanavir/ritonavir Blinding Care clinical Clinical improvement Clinical management Comorbidities confirmation Control control group COVID-19 COVID-19 diagnosis COVID-19 infection criteria defined determined by diagnosed Diagnosis discharge dissemination drug Drug administration drugs Efficacy and safety element eliminated enrolment exclusion criteria food Food and Drug Administration Gender group hospital hypersensitivity include inclusion criteria Infectious diseases information initiation of treatment Interaction intervention group Isolation lactating mechanical ventilation medication moderate moderate to severe multicentre Nasopharyngeal swab negativity Nigeria nitazoxanide number objective Ogun once daily Open-label open-label trial Ordinal Scale outcome measure Pan Pan African Clinical Trials Registry participant Patient PCR PCR test Phase 2 physician polymerase chain polymerase chain reaction positive pregnant Proportion of participant protocol quantified randomisation randomised randomised controlled trial receive receiving recruited REDCap Registered registry reported Ritonavir RT-PCR Saliva Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR SARS-CoV-2 polymerase chain reaction SARS-CoV-2 viral load secondary care sequence severe COVID-19 specialist Standard Standard of care state Stratification Study protocol supplementary material symptomatic Teaching Temporal the WHO time Treatment Trial Trial registration university Viral Viral load website working [DOI] 10.1186/s13063-020-04987-8 PMC 바로가기 [Article Type] Comparative Study
Diagnostic value of Chest CT and Initial Real-Time RT-PCR in COVID-19 InfectionOriginal Article Published on 2021-01-012022-10-29 Journal: Pakistan Journal of Medical Sciences [Category] COVID-19, [키워드] Admission age Chest CT clinical symptom Comorbidity correlated COVID-19 COVID-19 diagnosis CT finding CT findings diagnostic diagnostic value evaluate Fever FIVE headache hospital initial Isolation less measure onset of symptom Patient patients PCR test positive positively correlated PPV Presence presenting RT-PCR rtRT-PCR sensitivity Shortness of breath Symptom symptom duration the patient Turkey was performed [DOI] 10.12669/pjms.37.1.2956 PMC 바로가기 [Article Type] Original Article