Clinical presentation, therapeutic approach, and outcome of young patients admitted for COVID-19, with respect to the elderly counterpartCOVID-19로 입원한 젊은 환자의 고령 환자에 대한 임상 발표, 치료 접근법 및 결과Observational Study Published on 2021-05-012022-09-11 Journal: Clinical and experimental medicine [Category] SARS, 임상, 치료제, [키워드] Abnormalities Admission age association baseline characteristics Cancer Care Case fatality rate categories Characteristics chest X-ray clinical Cohort coronavirus disease Coronavirus disease 2019 COVID-19 creatinine Deceased discharged disease Dyspnea Elderly patient elderly patients evaluated fatality Fatality rate Gender Hospital admission ICU Impact IMV In-hospital in-hospital mortality in-hospital mortality rates increasing age information intensive care unit International Invasive mechanical ventilation leucocyte Mortality mortality rate mortality rates multicenter obesity Older outcome parameter Patient patients patients hospitalized positively correlated predictor presenting Prognosis prognosis of patient risk factor SARS-COV-2 infection tachypnea Therapeutic approach therapeutic approaches Treatment younger patients [DOI] 10.1007/s10238-021-00684-1 PMC 바로가기 [Article Type] Observational Study
Differential expression of angiotensin-converting enzyme-2 in human paranasal sinus mucosa in patients with chronic rhinosinusitisMain Articles Published on 2021-04-302022-10-30 Journal: The Journal of laryngology and otology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome angiotensin-converting enzyme 2 angiotensin-converting enzyme-2 chemokine Ciliated epithelial cells controls coronavirus Coronavirus-2 correlated Eosinophilic eosinophils eotaxin-3 ethmoid sinus examined expression immunoreactivity Infection Inflammation Inflammatory cytokine interleukin-1β Invasion investigated Messenger RNA mucosa objective paranasal sinus Patient patients polymerase chain positive cell positively correlated pro-inflammatory cytokines Quantitative receptor Regulation respiratory epithelium Result reverse transcription SARS-CoV-2 significant decrease sinusitis specimen susceptibility tumor necrosis factor-alpha tumour necrosis factor-α were assessed [DOI] 10.1017/S0022215121001225 PMC 바로가기 [Article Type] Main Articles
Survey on the Progression of Myopia in Children and Adolescents in Chongqing During COVID-19 PandemicPublic Health Published on 2021-04-282022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, MERS, SARS, [키워드] activity Adolescent applied average Cell children China Chongqing conducted contribute correlated correlation courses COVID-19 COVID-19 pandemic database enrolled evaluate incidence Increased myopia pandemic parameter per day Physique positively correlated Prevalence Prevent prevention progression provided quarantine questionnaire Randomly restrict Sample selected stratified student survey the mean visual acuity visual function [DOI] 10.3389/fpubh.2021.646770 PMC 바로가기 [Article Type] Public Health
Expression of the SARS-CoV-2 receptorACE2 in human heart is associated with uncontrolled diabetes, obesity, and activation of the renin angiotensin systemOriginal Investigation Published on 2021-04-272022-10-31 Journal: Cardiovascular Diabetology [Category] COVID-19, MERS, SARS, [키워드] ACE2 ACE2 expression ACE2 gene ACE2 mRNA Activation ADAM10 ADAM17 Angiotensin II angiotensin receptor blocker angiotensin-converting enzyme 2 Angiotensin-converting enzyme 2 receptor (ACE2) ARB ARBs ATII biopsies biopsy BMI body mass index clinical risk collected complex Corona virus 2 (SARS-CoV-2) correlated Degradation diabete diabetes Diabetic differentially expressed drug Ejection fraction entry of SARS-CoV-2 enzyme expressed expression facilitate Factor glycosylated heart heart tissue hearts hemoglobin higher risk human serum increase Infection infections infused inhibitor Injury investigated medication metformin mice no correlation obese patient obesity Patient plasma positively correlated protein expression RAS receptor Renin–angiotensin system blockers Result right SARS-CoV-2 serine protease serum severe disease Severe infection Support susceptibility tested the SARS-CoV-2 Therapies tissue TMPRSS2 treated Treatment virus was increased [DOI] 10.1186/s12933-021-01275-w PMC 바로가기 [Article Type] Original Investigation
Genomic and epidemiological characteristics of SARS-CoV-2 in Africa아프리카에서 SARS-CoV-2의 게놈 및 역학적 특성Research Article Published on 2021-04-262022-09-10 Journal: PLoS Neglected Tropical Diseases [Category] MERS, SARS, 변종, 유전자 메커니즘, [키워드] affected African analyzed Avian Influenza caused Characteristics Comorbidity continent coronavirus disease Coronavirus disease 2019 correlated correlation analyses Correlation analysis country COVID-19 death deaths early phase epidemiological European Factors fatality Fatality rate Genetic GISAID global pandemic infected cases Influenza initiative investigated isolate mortality rates mutant Mutation number of deaths number of infected occur ORF1 ORF1ab outbreak pandemic positively correlated RdRP regions S protein SARS-CoV-2 SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-CoV-2 sequence significantly Spread unique variant variants Wuhan [DOI] 10.1371/journal.pntd.0009335 PMC 바로가기 [Article Type] Research Article
Increased Serum Levels of Soluble TNF-α Receptor Is Associated With ICU Mortality in COVID-19 Patients가용성 TNF-α 수용체의 증가된 혈청 수준은 COVID-19 환자의 ICU 사망률과 관련이 있습니다Immunology Published on 2021-04-222022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus Admission age ARDS Biomarker cause Concentration coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 disease cytokine Cytokine storm death determinant determinants disease disease severity ELISA ESR Future greater healthy control healthy subjects ICU ICU patient ICU Patients Increased intensive care intensive care unit Iran laboratory-confirmed Laboratory-confirmed COVID-19 Level Mild Mortality non-ICU non-ICU patient non-ICU patients objective Older outcome Patient positively correlated receptor recruited respiratory respiratory distress Respiratory distress syndrome Result SARS-CoV-2 serum Serum level serum levels severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 severe COVID-19 disease severe COVID-19 patient severe COVID-19 patients severe disease significantly higher soluble TNF-α subject syndrome Tehran the healthy TNF-α TNF-α Ventilation [DOI] 10.3389/fimmu.2021.592727 PMC 바로가기 [Article Type] Immunology
Novel Predictors of COVID-19 Protective Behaviors Among US Adults: Cross-sectional SurveyOriginal Paper Published on 2021-04-202022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, SARS, [키워드] age Alter attribute Behavior Bivariate analyses communication conducted conspiracy beliefs contrary correlated COVID-19 COVID-19 knowledge COVID-19 knowledge score COVID-19 pandemic dependent variables driving effective Evidence Factor Gender Health health communication health information higher risk highest immune individual information interfere Intervention lack median message novel objective Other outcome outcomes pandemic positively correlated predictor predictors professional PROTECT protection Protective protective behavior Psychological psychological predictors Psychology public health Public health intervention reactance recommendations rejection remained reported Result significantly significantly lower social distancing Support survey Vaccine hesitancy virus yielding [DOI] 10.2196/23488 PMC 바로가기 [Article Type] Original Paper
The Uncounted Casualties of a Hidden COVID-19 Epidemic in China: Cross-sectional Study on Deaths Related to OverworkOriginal Paper Published on 2021-04-202022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, SARS, [키워드] age cardiovascular disease cardiovascular diseases casualty cause caused Cerebrovascular disease Characteristics China coded conditions correlation COVID-19 COVID-19 case COVID-19 crisis COVID-19 epidemic COVID-19 infection cross-sectional crowdsourced data death Deceased died essential worker examined First wave hazard Health incidence Intervention Mortality nonpharmaceutical intervention Nonpharmaceutical interventions objective on-duty deaths overwork overwork death Pearson correlation coefficient Policy positively correlated reported Result risk Sex Stress stroke web-based platform [DOI] 10.2196/23311 PMC 바로가기 [Article Type] Original Paper
The Impact of COVID-19 on Depressive Symptoms through the Lens of Sexual OrientationArticle Published on 2021-04-202022-10-28 Journal: Brain Sciences [Category] COVID-19, [키워드] added age arising Beck correlated COVID-19 COVID-19 negative Depression depressive symptom Depressive symptoms discrepancy expected explained Factor Fear of COVID-19 Gender Impact individual Len LGB people Linear regression analysis male mental health negative impact of COVID-19 Orientation pandemic participant Participants participated positively correlated provide Research responses sexual sexual orientation significant difference Symptom with COVID-19 women [DOI] 10.3390/brainsci11040523 PMC 바로가기 [Article Type] Article
Gut mycobiota alterations in patients with COVID-19 and H1N1 infections and their associations with clinical featuresArticle Published on 2021-04-132022-10-04 Journal: Communications Biology [Category] MERS, SARS, 바이오마커, 신종인플루엔자, [키워드] alteration analysed Aspergillus Aspergillus niger association Bacterial C-reactive protein Candida characterized clinical feature correlated COVID-19 COVID-19 patient COVID-19 patients CRP diarrhoea discharged Dysbiosis Effects fungal Fungal ecology fungi Gut H1N1 H1N1 infection had no HCs healthcare healthy control healthy controls IMPROVE Infectious diseases microbe microbiota Mild occur Patient patients patients with COVID-19 Penicillium positively correlated procalcitonin profile Sequencing severe symptom spacer the patient transcribed [DOI] 10.1038/s42003-021-02036-x PMC 바로가기 [Article Type] Article