Isolated generalized myoclonus immune-mediated by SARS-CoV-2: an illustrative videotaped caseSARS-CoV-2에 의한 면역 매개된 전신간대성 근간대성 근경련증: 예시적인 비디오 테이프 사례Case Reports Published on 2021-08-012022-09-11 Journal: Neurological Sciences [Category] MERS, SARS, 진단, 치료기술, [키워드] abnormality Admission Anosmia capture causal link chest CT scan clinical manifestation CNS confirmation COVID-19 COVID-19 infection CSF Diagnosis diagnostic generalized myoclonus hypoxic patients ICU IgM IgM and IgG immune Immune-mediated increasingly Infection Invasion Isolated medication Metabolic disorders movement Movement disorders Myoclonus Nasopharyngeal swab nasopharyngeal swabs Occurrence para positive predominant respiratory SARS-CoV-2 SARS-CoV-2 RNA detection Seroconversion serology steroid Steroids Symptom [DOI] 10.1007/s10072-021-05164-8 PMC 바로가기 [Article Type] Case Reports
SARS-CoV-2 genomic surveillance in Costa Rica: Evidence of a divergent population and an increased detection of a spike T1117I mutation코스타리카의 SARS-CoV-2 게놈 감시: 다양한 인구의 증거 및 스파이크 T1117I 돌연변이의 검출 증가Article Published on 2021-08-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] accumulating Analysis analyzed B.1 B.1.1 Cell clade Costa Rica country Course COVID-19 COVID-19 case COVID-19 pandemic D614G distribution Effectiveness evidence of feature Frequency Genome Genome sequencing genomic Genomic surveillance Genomic variability GISAID GISAID reported sequence increase in Infection Latin America less Lineage lineages Local Mutation no difference no differences nucleotide oligomerization ORF8 pandemic Pangolin lineage predicted predominant Prevalence Protein regions reported responsible SARS-CoV-2 SARS-CoV-2 genomic surveillance SARS-CoV-2 pandemic SARS-CoV-2 sequences sequence sequences Sequencing severity single nucleotide Spike protein Surveillance the SARS-CoV-2 the Spike Transmissibility Vaccine variant variant calling analysis variants virus whole genome whole-genome [DOI] 10.1016/j.meegid.2021.104872 PMC 바로가기 [Article Type] Article
Assessment of basic reproduction number (R 0), spatial and temporal epidemiological determinants, and genetic characterization of SARS-CoV-2 in Bangladesh방글라데시 SARS-CoV-2의 기본 생식 수(R 0), 공간 및 시간 역학 결정인자 및 유전적 특성 평가Article Published on 2021-08-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, 치료기술, 치료법, [키워드] Analysis assessment B.1 B.1.1 basic reproduction number calculated Case fatality rate circulating clade Cluster continuous monitoring country COVID-19 cumulative D614G detect determinants distribution effective Effectiveness epidemiological evaluate exponential growth Fatality rate Genetic Genome genomic Genomic analysis Genomic surveillance highest incidence of COVID-19 Infection isolates Lineage Local molecular molecular characteristics Molecular epidemiology Mutation Non-synonymous NSP11 NSP2 Nsp9 nucleocapsid nucleocapsid protein P323L pandemic Pangolin lineage performed Phylogenetic Phylogenetic analysis prediction predominant projection Protein RdRP SARS-CoV-2 SARS-CoV-2 sequence SARS-CoV-2 sequences SARS-CoV-2 strain sequence spike Spread strain Strains subsequent Surveillance Transmission dynamics unique vaccination variants of SARS-CoV-2 variations virus was recorded were recorded [DOI] 10.1016/j.meegid.2021.104884 PMC 바로가기 [Article Type] Article
Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort studyArticles Published on 2021-08-012022-10-31 Journal: The Lancet. Microbe [Category] COVID-19, MERS, SARS, [키워드] Admission Against age analysed antimicrobial available data Bacterial infection bloodstream carbapenem case report form caused CCP-UK characterisation clinical clinically Co-infection collected Community concerning conducted Critical care Culture demographic Department development diagnosed eligible England Enterobacteriaceae Escherichia coli European excluded female finding for inclusion foundation Frequency funding Haemophilus influenzae highest hospital Hospital admission hospitalised Imperial College London Infection Inpatient Intervention IQR ISARIC ISARIC WHO CCP-UK Laboratory likelihood median Medical Research Council Melinda Gate microbiologically multicentre NIHR NIHR HPRU organism outcome pandemic pathogen Pathogens Patient patients patients with COVID-19 predominant prospective cohort study protection recorded respiratory SARS-COV-2 infection SARS-CoV-2 test Secondary infection secondary infections secondary respiratory infections Staphylococcus aureus target therapeutic unit University of Liverpool Wellcome Trust were excluded were recorded WHO with COVID-19 [DOI] 10.1016/S2666-5247(21)00090-2 PMC 바로가기 [Article Type] Articles
Better prognosis in females with severe COVID-19 pneumonia: possible role of inflammation as potential mediatorObservational Study Published on 2021-08-012022-10-05 Journal: Clinical microbiology and infection : the official [Category] SARS, 바이오마커, 임상, [키워드] 95% CI Admission Analysis Better Biomarker C-reactive protein (CRP composite endpoint conducted COVID-19 COVID-19 pneumonia COVID-19 severity CRP death described Endpoint explain female Follow-up Hypothesis IMV Inflammation Invasive mechanical ventilation IQR less male median age mediation Mortality Observational cohort study PaO Patient patients potential mechanism predominant profile Prognosis progression provide retrospective risk risk of COVID-19 severe COVID-19 Severe COVID-19 pneumonia Sex sex differences significantly specific biomarker study period survival tested Variation [DOI] 10.1016/j.cmi.2020.12.010 PMC 바로가기 [Article Type] Observational Study
The eyes see what the mind seeks: a systematic review of abdominal imaging findings in patients with COVID-19Systematic Review Published on 2021-08-012022-10-27 Journal: The British Journal of Radiology [Category] COVID-19, MERS, [키워드] advance association bowel Coronavirus disease-19 COVID-19 database described distribution Evidence eye feature Final GI symptoms GI Tract Google Ground glass opacity help hepatic steatosis highlight imaging imaging abnormality increasingly Infarction Ischemia lung majority manifestation Manifestations nine organ Other pandemic pathophysiology Patient patients with COVID-19 positive predominant Prospective Study provide reported Research systematic literature search systematic review the disease the SARS-CoV-2 thrombosis Transmission vasculature was performed World Health Organization [DOI] 10.1259/bjr.20201220 PMC 바로가기 [Article Type] Systematic Review
Towards Fully Integrated Portable Sensing Devices for COVID-19 and Future Global Hazards: Recent Advances, Challenges, and ProspectsReview Published on 2021-07-312022-10-30 Journal: Micromachines [Category] COVID-19, [키워드] assays CMOS CMOS technology complementary Contamination coronavirus 2 coronavirus disease COVID-19 death Device diagnostic fatal disease Future group hazards Infectious disease less pandemic platform point-of-care portable sensing devices predominant Prevent recent reliability reported researcher respiratory SARS-CoV-2 Spread [DOI] 10.3390/mi12080915 PMC 바로가기 [Article Type] Review
Profiling of Oral Microbiota and Cytokines in COVID-19 PatientsMicrobiology Published on 2021-07-302022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] 16S rRNA ACE2 acute respiratory syndrome Analysis angiotensin-converting enzyme 2 Area AUC automated Bacterial Biomarker clinics consortia Control controls coronavirus COVID-19 COVID-19 patients COVID-19 susceptibility Curve Cytokines demonstrated evidenced group highlighting immunoassays Inflammatory introduced local inflammation machine learning metagenomics microbiota (D064307) mucosa multiplex network analysis oral oral microbiota parameter Patient pilot study predict predominant Prevotella pro-inflammatory cytokine Profiling protease recent reduce Saliva SARS-CoV-2 secreted Sequencing serine 2 serum samples severe coronavirus disease Specy sputum subject subjects Symptoms TMPRSS2 Transcriptome transmembrane Transmission two group Viral RNA [DOI] 10.3389/fmicb.2021.671813 PMC 바로가기 [Article Type] Microbiology
Phylogenetic analysis of SARS-CoV-2 lineage development across the first and second waves in Eastern Germany in 2020: insights into the cause of the second wave2020년 동독의 1차 및 2차 유행에 걸친 SARS-CoV-2 계통 발생 계통발생 분석: 2차 유행의 원인에 대한 통찰력Short Paper Published on 2021-07-302022-09-11 Journal: Epidemiology and Infection [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case driving Epidemiology First wave genomic Germany initiated introduced Lineage Mild Phylogenetic analysis predominant prevalent Region respiratory SARS-CoV-2 SARS-CoV-2 lineage second wave severe acute respiratory syndrome Coronavirus variant variants Winter [DOI] 10.1017/S0950268821001461 PMC 바로가기 [Article Type] Short Paper
Mechanics Insights of Alpha-Lipoic Acid against Cardiovascular Diseases during COVID-19 InfectionReview Published on 2021-07-262022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] “cytokine storm” ACE2 acid Activation acute respiratory syndrome addition alpha-lipoic acid alveolar cells Analysis anti-inflammatory effect antioxidant appear ARDS binding blood vessels cardiovascular cardiovascular comorbidity cardiovascular disease caused cellular entry Coagulopathy complex Complication contribute coronavirus Coronavirus disease 2019 COVID-19 COVID-19 complications COVID-19 infection Critical critical condition death distress distribution dysfunction endothelial Endothelial cell Endothelial dysfunction endothelial function Endothelium Evolution expressed global pandemic high risk homeostasis human Angiotensin-converting enzyme immune system IMPROVE independent induce infected with SARS-CoV-2 Infection Inflammation information insight interfere lung Mechanics mechanism microthrombi mitochondrial Mitochondrial function multiorgan failure Myocardial infarction nitric oxide oxidative stress pathology pathway Patient Perspective predominant Prognosis proinflammatory protease Protein reactive oxygen specy receptor redox status reduced reported Respiratory disease SARS-CoV-2 SARS-COV-2 infection serine 2 severe COVID-19 signaling pathways small intestine Spread stroke the S protein the SARS-CoV-2 therapeutic therapy thrombosis tissue TMPRSS2 transmembrane underlying diseases upregulation viral infection viral surface virus Wuhan, China [DOI] 10.3390/ijms22157979 PMC 바로가기 [Article Type] Review