The historical aspects of vaccination in pregnancyArticle Published on 2020-10-132023-06-14 Journal: Best practice & research. Clinical obstetrics & gynaecology [Category] MERS, SARS, [키워드] Influenza pertussis Pregnancy rubella Tetanus Vaccines [DOI] 10.1016/j.bpobgyn.2020.09.005 PMC 바로가기
Estimating the Percentage of a Population Infected with SARS-CoV-2 Using the Number of Reported Deaths: A Policy Planning ToolArticle Published on 2020-10-132022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] Accuracy approach coronavirus country COVID19 death deaths dependent on estimate Fatality rate help immune IMPROVE Infection less Low- and middle-income countries magnitude number percentage Planning Policy Population population immunity populations Prevalence public health authority reported SARS-CoV-2 SARS-CoV-2 antibody Sero-prevalence serology Vaccines widespread [DOI] 10.3390/pathogens9100838 PMC 바로가기 [Article Type] Article
Biomedical Science to Tackle the COVID-19 Pandemic: Current Status and Future PerspectivesReview Published on 2020-10-112022-10-30 Journal: Molecules [Category] COVID-19, MERS, SARS, [키워드] addressed approach approaches caused clinical trials combating coronavirus coronavirus 2 COVID-19 current diagnostic diagnostics epidemiologists Future Health healthcare Infection Infectious disease knowledge management mechanisms medical doctors nanomedicine pandemic Pandemics Perspective prevention Protein raised reported respiratory Safe SARS-CoV-2 Science solution status survival Symptoms tested the SARS-CoV-2 virus therapy Treatment unique urgency Vaccine Vaccines while [DOI] 10.3390/molecules25204620 PMC 바로가기 [Article Type] Review
In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hingesResearch Article Published on 2020-10-092022-10-28 Journal: Science (New York, N.y.) [Category] COVID-19, Fulltext, SARS, [키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 antibody binding cell entry contribute coronavirus coronavirus spike protein domain engage explain flat glycan glycosylated glycosylation host cell host cell surface Molecular dynamics simulation Neutralizing antibodies occurred prefusion conformation receptor required reveal Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike Science spike Spike protein Structural analysis tomography Vaccine development Vaccines viral entry viral surface virions [DOI] 10.1126/science.abd5223 PMC 바로가기 [Article Type] Research Article
Evolutionary Analysis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reveals Genomic Divergence with Implications for Universal Vaccine EfficacyArticle Published on 2020-10-082022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome alteration Amino acid Analysis caused conducted coronavirus coronavirus 2 COVID-19 disease Divergence E protein early stage Efficacy effort faster Genes Genome genomic genomic divergence implication increase in investigation isolate lack M protein mapped mutations N protein observation outbreak outlined pandemic Phylogenetic analysis Phylogeny public health Region reported respiratory S protein SARS-CoV-2 similarity target target region Transmission Universal Vaccine vaccine candidate vaccine candidates Vaccine development Vaccines Variation Wuhan [DOI] 10.3390/vaccines8040591 PMC 바로가기 [Article Type] Article
Experimental and in silico evidence suggests vaccines are unlikely to be affected by D614G mutation in SARS-CoV-2 spike proteinBrief Communication Published on 2020-10-082022-10-04 Journal: NPJ Vaccines [Category] 변종, [키워드] Affect affected approach cleavage site comparable COVID-19 vaccine D614G mutation dose Efficacy Evidence experimental evidence ferret glycoprotein in silico INO-4800 introduced lack Mutation neutralisation assay performed Proteases RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 spike protein sera shown Spike protein Support supported the SARS-CoV-2 unlikely Vaccine Vaccines viral evolution virus isolate [DOI] 10.1038/s41541-020-00246-8 PMC 바로가기 [Article Type] Brief Communication
Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral ResponseArticle Published on 2020-10-072024-08-28 Journal: Cell Host & Microbe [Category] 말라리아, [키워드] antibody antibody feedback B cells Ig-knockin mice malaria Plasmodium falciparum Vaccines
Towards integrated surveillance-response systems for the prevention of future pandemicsOpinion Published on 2020-10-072022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, Fulltext, MERS, SARS, 조류인플루엔자, [키워드] approach Bank contribute COVID-19 pandemic cumulative disease drug engage Evidence Health highest Host Human human pathogen inquiry Integrated surveillance-response Italy means MOST one health outbreak Outbreaks Pandemics pathogen Prevent Research reservoirs risk Surveillance Transdisciplinarity Transmission Vaccines West Nile Virus zoonose zoonoses zoonotic zoonotic origin [DOI] 10.1186/s40249-020-00757-5 PMC 바로가기 [Article Type] Opinion
Is smaller better? Vaccine targeting recombinant receptor-binding domain might hold the key for mass production of effective prophylactics to fight the COVID-19 pandemicResearch Highlight Published on 2020-10-062022-10-29 Journal: Signal Transduction and Targeted Therapy [Category] COVID-19, MERS, SARS, [키워드] Adaptive immunity COVID-19 pandemic domain effective Infectious diseases Vaccines [DOI] 10.1038/s41392-020-00317-1 PMC 바로가기 [Article Type] Research Highlight
Evidence of a wide gap between COVID-19 in humans and animal models: a systematic reviewResearch Published on 2020-10-062022-11-01 Journal: Critical Care [Category] COVID-19, MERS, [키워드] animal animal model animal models bioRxiv clinical manifestations Coagulopathy COVID-19 criteria Cytokine storm death elicited Endpoint English evidence of ferret ferrets full recovery hamster hamsters high viral replication Human hypoxemic inclusion criteria Lower respiratory tract Lung pathology macaques medRxiv mice Mild Mortality MOST multiple organ dysfunction non-human primate Other pandemic peer-reviewed study phenotype Prophylaxis Protective reported Research Respiratory failure Result review rodent SARS-CoV-2 searched specific IgG antibody Spike proteins supported systematic review systemic inflammation the MEDLINE Therapies Transient Vaccines [DOI] 10.1186/s13054-020-03304-8 PMC 바로가기 [Article Type] Research