Rapid identification of SARS-CoV-2 in the point-of-care using digital PCR-based Dr. PCR™ Di20K COVID-19 Detection Kit without viral RNA extraction바이러스 RNA 추출 없이 디지털 PCR 기반 Dr. PCR™ Di20K COVID-19 Detection Kit를 사용하여 현장 진료에서 SARS-CoV-2의 신속한 식별Article Published on 2022-05-012022-09-11 Journal: Genes & genomics [Category] COVID19(2023년), SARS, 치료기술, [키워드] 2019-nCoV addition assessment biosafety Concordance Contamination COVID-19 cross-over detection Diagnosis diagnostic diagnostic sensitivity diagnostic test diagnostic tests dPCR evaluate evaluated Kappa coefficient limitation pandemic performed POCT point-of-care point-of-care testing pre-diagnosis previous study qRT-PCR Rapid reliability reported RNA extraction SARS-CoV-2 sensitivity Sensitivity and specificity Space specificity specimen Spread the WHO viral RNA extraction was measured were measured [DOI] 10.1007/s13258-022-01242-z PMC 바로가기 [Article Type] Article
Analytical sensitivity and clinical performance of “COVID-19 RT-PCR Real TM FAST (CY5) (ATGen, Uruguay) and “ECUGEN SARS-CoV-2 RT-qPCR” (UDLA-STARNEWCORP, Ecuador)”: High quality-low cost local SARS-CoV-2 tests for South America"COVID-19 RT-PCR Real TM FAST (CY5) (ATGen, Uruguay) 및 "ECUGEN SARS-CoV-2 RT-qPCR" (UDLA-STARNEWCORP, Ecuador)"의 분석 민감도 및 임상 성능: 고품질-저비용 남미 지역 SARS-CoV-2 테스트Article Published on 2022-04-132022-09-11 Journal: PLoS Neglected Tropical Diseases [Category] COVID19(2023년), SARS, 치료기술, [키워드] 2019-nCoV analytical sensitivity approach authorization Brazil contributed country COVID-19 pandemic Diagnosis diagnostic Ecuador Emergency Emergency use authorization EUA evaluated FDA gold gold standard IMPROVE Infectious disease Infectious diseases limit of detection Local overcome produced reduce regulatory agencies RNA extraction RT-PCR RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RT-PCR SARS-CoV-2 test SARS-CoV-2 tests SARS-CoV2 detection sensitivity South South America specificity supply shortage Supply shortages Surveillance TaqMan Thermofisher USA [DOI] 10.1371/journal.pntd.0010082 PMC 바로가기 [Article Type] Article
COVID-19 Australia: Epidemiology Report 59 Reporting period ending 13 March 2022Article Published on 2022-04-122023-07-08 Journal: Communicable diseases intelligence (2018) [Category] COVID19(2023년), [키워드] 2019-nCoV acute respiratory disease Australia Coronavirus disease 2019 COVID-19 Epidemiology Novel coronavirus SARS-CoV-2 [DOI] 10.33321/cdi.2022.46.25
Role Of Ct Chest As First Choice For Early Diagnosis Of Covid-19 Pneumonia Even In Rt-Pcr Negative CaseCase Reports Published on 2022-04-012023-07-09 Journal: Journal of Ayub Medical College, Abbottabad : JAMC [Category] COVID19(2023년), [키워드] 2019-nCoV COVID-19 hrct chest Real Time RT-PCR. SARS-CoV-2 [DOI] 10.55519/JAMC-02-9127 [Article Type] Case Reports
In silico analysis of the interactions of certain flavonoids with the receptor-binding domain of 2019 novel coronavirus and cellular proteases and their pharmacokinetic properties특정 플라보노이드와 2019년 신종 코로나바이러스 수용체 결합 도메인의 상호작용 및 세포성 프로테아제 및 이들의 약동학적 특성에 대한 실리코 분석Article Published on 2022-04-012022-09-11 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 치료제, [키워드] 2019 2019 novel coronavirus 2019-nCoV acute respiratory syndrome coronavirus Analysis binding blood-brain barrier cathepsin B caused cellular protease cellular proteases Compound conducted coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 death drug-likeness eukaryotic cells evaluated FIVE flavonoid flavonoids gallate glycoprotein hepatotoxicity hydrogen Hydrogen bond inhibit Interaction interactions microorganism MM/PBSA molecular molecular docking molecular dynamics Molecular mechanics nCoV P-glycoprotein pharmacokinetic Protein Proteins RBD Receptor binding domain respiratory SARS-CoV-2 Serine serine protease severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike glycoprotein subgroup substrate supported surface area target proteins the receptor-binding domain TMPRSS2 Toxicity transmembrane serine protease transmembrane serine protease 2 Van [DOI] 10.1080/07391102.2020.1840444 PMC 바로가기 [Article Type] Article
The governance of imported 2019-nCov infections: What can be learned from China’s experience?수입된 2019-nCov 감염의 거버넌스: 중국의 경험에서 무엇을 배울 수 있습니까?Perspective Published on 2022-03-092022-09-10 Journal: Global Health Research and Policy [Category] SARS, 변종, [키워드] 2019-nCoV China Community Complete country COVID-19 Defense Delta Disinfection Epidemic exposure to global pandemic Government illegal immigration Imported infection indicate Infection information information management International leadership Local local outbreaks management measure nCoV omicron Omicron variants outbreak outlined Policy implication Prevention and control quarantine Regulation required Safe Spread suggested target variant vector [DOI] 10.1186/s41256-022-00243-5 PMC 바로가기 [Article Type] Perspective
Mass COVID-19 patient screening using UvsX and UvsY mediated DNA recombination and high throughput parallel sequencingUVSX 및 UVSY 매개 DNA 재조합 및 높은 처리량 병렬 시퀀싱을 사용한 질량 COVID-19 환자 스크리닝Article Published on 2022-03-082022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 유전자 메커니즘, 치료기술, [키워드] 2019 novel coronavirus 2019-nCoV Amplicon amplicons amplification approach Bioinformatics analysis Community Containment coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 patient detect develop DNA downstream fatigue Fever foundation Generation Genome High-throughput screening Illumina include individuals Infection Isolation isothermal life-threatening mass Mediated Medical conditions Molecular assay molecular assays non-infectious Novel coronavirus Patient per day platform protocol REcombinase Recombination REMBRANDT respiratory respiratory symptom RNA virus SARS-CoV-2 Sequencing Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 Shortness of breath Symptom Symptomatic patients [DOI] 10.1038/s41598-022-08034-1 PMC 바로가기 [Article Type] Article
SARS-CoV-2 and Coronavirus Disease Mitigation: Treatment Options, Vaccinations and VariantsReview Published on 2022-02-202022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] 2019-nCoV addition caused China co-morbidities conducted COVID-19 Effectiveness effort globe individual Infection International knowledge measure morbidity and mortality Novel coronavirus overcome pandemic pandemic disease Pandemics persistence polymorphic variant Prevent question raise SARS-CoV-2 Stage Transmissibility treat Treatment vaccination Vaccine Vaccines variant variants [DOI] 10.3390/pathogens11020275 PMC 바로가기 [Article Type] Review
A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflammatory Responses in the Syrian Hamster Model of SARS-CoV-2 Infection새로운 글루코코르티코이드 및 안드로겐 수용체 조절제는 SARS-CoV-2 감염의 시리아 햄스터 모델에서 바이러스 진입 및 선천성 면역 염증 반응을 감소시킵니다Immunology Published on 2022-02-162022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료제, [키워드] 2019-nCoV 2019-nCoV/USA-WA1/2020 ACE2 acting Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered administration amplify Analysis androgen Androgen receptor angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 animal animals antagonist antagonists bind caused CD4 Cell clinical development Clinical studies clinical study coronavirus COVID-19 Critical days post-infection decrease Defense domain dose-dependent DPI Efficacy enzyme examined expression glucocorticoid Glucocorticoid receptor golden hamster hamster Host host defense humans IL-6 indicated infiltration Inflammation inflammatory lung injury Inflammatory response Innate innate immune Innate immunity intranasally lack lung Lung histopathology Lung injury lung tissue Macrophage macrophages mechanism mechanism of action Model modulator molecular docking studies Molecular docking study novel oral administration outcome patients Phylogenetic analysis positive Predictive Prevent progression protease Protein PT150 receptor receptors reduce regulated Replication replication of SARS-CoV-2 required Research respiratory response Result SARS – CoV – 2 SARS-CoV-2 SARS-COV-2 infection sequence identity Serine serine 2 severe acute respiratory syndrome Coronavirus shown strain surface protein T-cell T-cells TCID the cell therapeutic therapeutic efficacy Therapeutics tissue damage tissue injury TMPRSS2 transcriptional repressor transcriptionally transmembrane Treatment USA-WA1/2020 variants variants of SARS-CoV-2 Viral viral entry Viral load virus were infected [DOI] 10.3389/fimmu.2022.811430 PMC 바로가기 [Article Type] Immunology
Long persistence of severe acute respiratory syndrome coronavirus 2 swab positivity in a drowned corpse: a case reportCase Report Published on 2022-02-092022-10-30 Journal: Journal of Medical Case Reports [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] 2019-nCoV acute respiratory syndrome Asymptomatic Autopsy Case report Contagion coronavirus COVID-19 COVID-19 on drowned cadaver dead death evaluate highlight initial viral load Italy knowledge lack Long Nasopharyngeal swab performed persistence Postmortem positivity Postmortem swab risk SARS-CoV-2 Specific Spread subject Swab swabs TaqMan Thermo Fisher Scientific viral genome virus was used [DOI] 10.1186/s13256-022-03297-8 PMC 바로가기 [Article Type] Case Report