active treatment – Page 3 – Communicable Diseases Research

Management of prostate cancer radiotherapy during the COVID-19 pandemic: A necessary paradigm change

코로나19 팬데믹(세계적 대유행) 중 전립선암 방사선 치료의 관리: 필요한 패러다임의 변화

Review

Published on 2021-01-012022-09-11
Journal: Cancer treatment and research communications [Category] 바이오마커,

A randomized, multicentre, open-label phase II proof-of-concept trial investigating the clinical efficacy and safety of the addition of convalescent plasma to the standard of care in patients hospitalized with COVID-19: the Donated Antibodies Working against nCoV (DAWn-Plasma) trial

COVID-19로 입원한 환자의 표준 치료에 회복기 혈장 추가의 임상 효능과 안전성을 조사하는 무작위, 다기관, 공개 라벨 2상 개념 증명 시험: nCoV에 대항하는 기증된 항체(DAWn- 플라즈마) 시험

Clinical Trial

Published on 2020-11-272022-08-13
Journal: Trials [Category] SARS, 임상, 진단,

[키워드] absence active treatment addition administration Belgium Bronchoalveolar lavage Clinical efficacy clinical status convalescent plasma COVID-19 infection COVID-19 pandemic defined diagnosed with COVID-19 Diagnosis diagnosis of COVID-19 died Effect eligible feature Health care Health care system health care systems Hospitalized hospitalized patient hospitalized patients Immunity include Infection Influenza information Intervention mechanical ventilation Mortality multicentre nCoV novel SARS-CoV-2 virus Open-label Ordinal Scale past Patient patients hospitalized PCR primary endpoint proof-of-concept clinical trial proportion radiological randomization Randomized receive recruit Registered Safe SARS-CoV-2 virus secondary endpoint Standard of care study inclusion supplementary material Support Swab symptomatic the disease the WHO Treatment treatment group Trial Trial registration with COVID-19 working
[DOI] 10.1186/s13063-020-04876-0 PMC 바로가기 [Article Type] Clinical Trial

COVID-19 and pneumothorax: a multicentre retrospective case series

COVID-19와 기흉: 다기관 후향적 사례 시리즈

Original Articles

Published on 2020-11-192022-09-06
Journal: The European Respiratory Journal [Category] Communicable Disease, COVID-19, Fulltext, SARS,

[키워드] acidosis active treatment addition age case sery clinical Clinical management clinically collected complicate Complication complication of COVID-19 coronavirus disease Coronavirus disease 2019 COVID-19 demographics described develop diagnosis of COVID-19 extracorporeal membrane oxygenation female hospital Hospital admission incidence inclusion criteria independent individual inpatient admission Intubated Laboratory laboratory investigations Lung disease males marker mechanical ventilation medical record multicentre not different not significantly different occur pathology Patient patients Pneumomediastinum pneumothorace pneumothoraces Pneumothorax poor prognosis radiology Result retrospective significantly lower survival Treatment UK hospital UK hospitals Ventilated with COVID-19
[DOI] 10.1183/13993003.02697-2020 PMC 바로가기 [Article Type] Original Articles

Impact of the COVID-19 Pandemic on Patient-Reported Outcomes of Breast Cancer Patients and Survivors

코로나19 팬데믹이 유방암 환자 및 생존자의 환자 보고 결과에 미치는 영향

Multicenter Study

Published on 2020-11-052022-09-11
Journal: JNCI Cancer Spectrum [Category] SARS, 임상,

[키워드] 95% confidence interval active treatment affected Analysis Breast Breast cancer breast cancer patient breast cancer patients Cancer change Cohort collected conducted confounders Contact core coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic Deterioration emotional European evaluated general practitioner HADS Impact implementation improvement Intervention intervention study less life lockdowns loneliness management Measures mental health moderate moderate to severe multicenter Multiple organization outcome pandemic Participants Patient physical physician pros Quality Quality of life questionnaire reported resulting scale social distancing social interaction statistically significant survivor Survivors threshold treated Treatment Well-being
[DOI] 10.1093/jncics/pkaa104 PMC 바로가기 [Article Type] Multicenter Study

Managing the front-line treatment for diffuse large B cell lymphoma and high-grade B cell lymphoma during the COVID-19 outbreak

COVID-19 발생 기간 동안 미만성 거대 B 세포 림프종 및 고급 B 세포 림프종에 대한 최전선 치료 관리

Article

Published on 2020-11-012022-09-11
Journal: British Journal of Haematology [Category] SARS, 진단, 치료제,

Lopinavir–ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

COVID-19로 병원에 입원한 환자의 Lopinavir-ritonavir(RECOVERY): 무작위, 통제, 공개, 플랫폼 시험

Randomized Controlled Trial

Published on 2020-10-242022-08-13
Journal: Lancet (London, England) [Category] 임상,

[키워드] 28-day mortality 95% CI active treatment all-cause mortality allocation concealment assigned Azithromycin baseline both groups by mouth composite endpoint death Dexamethasone died discharge discharged eligible finding funding groups hospital Hospital stay Hydroxychloroquine IMPROVE in both groups in vitro activity intention-to-treat basis Invasive mechanical ventilation ISRCTN Lopinavir Lopinavir–ritonavir median Medical Research Council mouth no significant difference observational studies Open-label outcome Participants Patient Platform trial preclinical studies Primary outcome proportion randomisation randomised Randomised trial Randomly rate ratio receive recovery reductions reductions in Registered Result risk risk ratio Ritonavir Standard of care subgroups of patients Support the patient treat Treatment treatment for COVID-19 treatment group Trial usual care web-based simple with COVID-19
[DOI] 10.1016/S0140-6736(20)32013-4 PMC 바로가기 [Article Type] Randomized Controlled Trial

Efficacy of an online cognitive behavioral therapy program developed for healthcare workers during the COVID-19 pandemic: the REduction of STress (REST) study protocol for a randomized controlled trial

COVID-19 전염병 동안 의료 종사자를 위해 개발된 온라인 인지 행동 치료 프로그램의 효능: 무작위 대조 시험을 위한 STress 감소(REST) 연구 프로토콜

Study Protocol

Published on 2020-10-212022-08-13
Journal: Trials [Category] MERS, SARS, 임상,

[키워드] ‘My Health too’ CBT program acceptability Accessibility active control group active treatment assessment assessments behavioral therapy bibliotherapy CBT CBT program Chinese circumvent Clinical practice cognitive cognitive behavioral therapy consequence COVID-19 COVID-19 epidemic COVID-19 pandemic credibility decrease Depression effective Efficacy epidemic peak evaluate evidence-based psychological treatment evidence-based psychological treatments expected facilitate flexibility Follow-up Health Health crisis healthcare Healthcare systems healthcare worker Healthcare workers healthcare workers’ mental health immediate perceived stress immediate stress include Insomnia Internet-Based Intervention internet-based interventions long-lasting management mental health mental health toll Online CBT online CBT program open open trial outcome pandemic status Perceived Stress Scale Population Post-traumatic stress disorder prevalence rate prevalence rates Primary outcome Program PSS-10 PSS-10 score PSS-10 scores psychiatric disorder Psychiatric disorders psychological disorder psychological disorders Psychological distress PTSD random assignment Randomized controlled trial Registered reported required Resilience REST Rumination Satisfaction secondary Secondary outcomes significantly sleep disorders Stress stress level stress levels stress-related disorder stress-related disorders Study protocol systemic impact the disease the epidemic therapy Treatment Trial registration
[DOI] 10.1186/s13063-020-04772-7 PMC 바로가기 [Article Type] Study Protocol

Breath Regulation and yogic Exercise An online Therapy for calm and Happiness (BREATH) for frontline hospital and long-term care home staff managing the COVID-19 pandemic: A structured summary of a study protocol for a feasibility study for a randomised controlled trial

호흡 조절 및 요가 운동 COVID-19 대유행을 관리하는 최전선 병원 및 장기 요양원 직원을 위한 평온과 행복을 위한 온라인 치료(BREATH): 무작위 대조 시험에 대한 타당성 연구를 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2020-07-142022-08-13
Journal: Trials [Category] SARS, 임상,

[키워드] 1:1 active treatment All study participant All study participants allocation concealment Analysis Anxiety ARMS blinded Blinding breath breaths Canada Care collected Complete Completeness completion consent form control arm Controlled trial COVID-19 COVID-19 pandemic COVID-19 patient data entry Depression determine dissemination element eligibility English enhancement exercise feasibility feasible foundation Group allocation Health Health promotion Healthcare staff healthcare worker Healthcare workers healthy hospital IMPROVE include Insomnia interactive module Intervention involved London Long-term care management measure medium mental health mind-body intervention mindfulness Mindfulness-based muscle relaxation music therapy number objective offered online session Open-label outcome participant phase Phase I physical Prevent Program progressive muscle relaxation promotion protocol Psychoeducation randomised randomised controlled trial randomization randomize Randomized Randomized controlled trial RCT recruited recruitment REDCap reduce Research researcher Resilience resiliency retention Sample size scheduling significantly status study hypothese study hypotheses Study protocol subsequent supervision therapy Treatment Trial USA website Weekly windows Work stress yoga
[DOI] 10.1186/s13063-020-04583-w PMC 바로가기 [Article Type] Letter

Safety and immunogenicity of a multivalent HIV vaccine comprising envelope protein with either DNA or NYVAC vectors (HVTN 096): a phase 1b, double-blind, placebo-controlled trial

DNA 또는 NYVAC 벡터(HVTN 096)가 있는 외피 단백질을 포함하는 다가 HIV 백신의 안전성 및 면역원성: 1b상, 이중 맹검, 위약 대조 시험

Article

Published on 2019-10-072022-09-06
Journal: The Lancet. HIV [Category] Communicable Disease,

[키워드] active treatment Administered administration adverse event allergy antibodies antibody Antibody Response Antibody responses antibody-dependent cell-mediated cytotoxicity approach assigned binding binding antibody boost Cell-mediated cytotoxicity Combination component computer-generated Coverage cranial cytotoxicity died DNA dose doses double-blind early administration effective Efficacy enrolled envelope protein epitope finding followed by foundation funding glycoprotein gp120 healthy healthy volunteer healthy volunteers HIV infection HIV vaccine IgG IgG response IgG responses immunogenicity individual Infection Infectious diseases injection Lymphadenopathy marker measure Melinda Gate Melinda Gates motor vehicle Neutralising Antibodies outcome participant Participants Placebo placebo group placebo-controlled placebo-controlled trial Primary outcomes priming product Protein purified random Randomly reactogenicity regimen Registered responses risk Safety screened Serious Adverse Event Serious Adverse Events Switzerland the placebo group the vaccine trauma Treatment treatment group treatment groups Trial trials vaccination vaccination schedule Vaccinations Vaccine vector Volunteer
[DOI] 10.1016/S2352-3018(19)30262-0 PMC 바로가기 [Article Type] Article