Immunogenicity and safety of two-dose SARS-CoV-2 vaccination via different platforms in kidney transplantation recipientsArticle Published on 2022-09-162022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] acute respiratory syndrome Administered adverse effect analyzed Anti-spike antibody BNT162b2 cellular cellular response Cellular responses ChAdOx1 Characteristics coronavirus creatinine Efficacy elicited first dose highest humoral immunogenicity interferon-γ kidney kidney transplant mRNA mRNA1273 Patient patients platform positive Protein Protein subunit recipient rejection renal function SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine second dose the patient the spike protein vaccination Vaccination strategy Vaccine Vaccines Viral vector [DOI] 10.3389/fimmu.2022.951576 PMC 바로가기
MiRNA-SARS-CoV-2 dialogue and prospective anti-COVID-19 therapiesMiRNA-SARS-CoV-2 대화 및 전향적인 항-COVID-19 치료법Review Published on 2022-09-152022-09-11 Journal: Life sciences [Category] COVID19(2023년), MERS, SARS, 바이오마커, 변종, 비임상, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 adverse effect adverse effects Affect antiviral response approach approved Biomarker caused Cell signaling chance Clinical significance Comorbidities coronavirus Coronavirus-2 country COVID-19 COVID-19 illness COVID-19 infection COVID-19 pathogenesis COVID-19 patient Critical death detect differential expression disease disease onset disease pathology effort etiology expression FDA focus Host host cell host inflammatory response host miRNA host miRNAs identify Infection life cycle microRNA miRNA miRNAs molecular interaction non-coding RNA offer pathogen Pathogen-host interaction patients with COVID-19 post-transcriptionally quest reduce respiratory respond RNA RNA silencing SARS Coronavirus SARS coronavirus 2 SARS coronavirus 2. SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 virus Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severity Signaling target gene the SARS-CoV-2 virus therapy treat Treatment Viral viral miRNA viral miRNAs [DOI] 10.1016/j.lfs.2022.120761 PMC 바로가기 [Article Type] Review
Aseptic osteonecrosis of the maxilla after severe COVID-19 infection and its treatmentCase report Published on 2022-09-012022-10-05 Journal: Radiology Case Reports [Category] 진단, 치료법, [키워드] adverse effect Affect Antibiotics Aseptic Complication complications concerning Course COVID-19 expected Glucocorticoids hypotheses Infection inhibitors interleukin-6 investigated joint majority Maxilla mechanism medication new SARS-CoV-2 osteonecrosis Respiratory system Severe COVID-19 Infection subject suffered the disease therapeutic tissue treat Treatment underlying disease [DOI] 10.1016/j.radcr.2022.06.009 [Article Type] Case report
Review of embryo-fetal developmental toxicity studies performed for pharmaceuticals approved by FDA in 2020 and 2021.Research article Published on 2022-09-012022-10-05 Journal: Reproductive toxicology (Elmsford, N.Y.) [Category] 비임상, [키워드] adopted adverse effect approvals approved clinician conducted developmental drug drugs FDA information majority monoclonal antibody non-human primate performed Pregnancy recommendation review risk rodent rule tested therapeutic Toxicity while [DOI] 10.1016/j.reprotox.2022.06.012 [Article Type] Research article
IGHG3 hinge length variation was associated with the risk of critical disease and death in a Spanish COVID-19 cohortArticle Published on 2022-09-012022-11-15 Journal: Genes and Immunity [Category] SARS, 진단, [키워드] 95% CI adverse effect Affect allele Amino acid carrier cohorts COVID-19 COVID-19 cohort Critical Critical disease death explained functions genotyped ICU IgG3 IGHG3 immune adaptive response impair increased risk induce less moderate-severe Mortality neutralization Patient phagocytosis plasma polymorphism reduce reduced risk risk of COVID-19 risk of death S allele SARS-CoV-2 sequence severity Spanish Variation viral neutralization [DOI] 10.1038/s41435-022-00179-3 PMC 바로가기
A third dose of the BNT162b2 mRNA vaccine significantly improves immune responses among liver transplant recipientsBNT162b2 mRNA 백신의 세 번째 접종은 간 이식 환자의 면역 반응을 크게 향상시킵니다Article Published on 2022-09-012022-09-12 Journal: Journal of hepatology [Category] Fulltext, MERS, 진단, [키워드] Adverse adverse effect adverse effects age Anti-RBD IgG anti-SARS-CoV-2 antibody Antibody Response binding domain BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccine Booster vaccine cellular immune responses cellular response center correlated determine dose doses Effect evaluate evaluated Factor fatigue Follow-up geometric humoral humoral immune response IgG immune immune response Immunity Immunosuppression immunosuppressive medications IMPROVE inhibitor liver liver transplant recipients local pain majority male median age Mild monotherapy neutralizing antibody Older age Patient predict RBD recipient recipients reported response Side effect side effects BNT162b2 mRNA vaccine significantly solid organ transplant T-cell the patient third dose Treatment Vaccine vaccine dose [DOI] 10.1016/j.jhep.2022.03.042 PMC 바로가기 [Article Type] Article
Liposome encapsulated clodronate mediated elimination of pathogenic macrophages and microglia: A promising pharmacological regime to defuse cytokine storm in COVID-19Review article Published on 2022-09-012022-10-05 Journal: Medicine in Drug Discovery [Category] 신약개발, 치료제, [키워드] activated macrophage Activation administration adverse effect alleviate Brain Clinical management Clodronate COVID-19 COVID-19 vaccine COVID-19 vaccines Cytokine storm death depleting discharge dysregulation encapsulation event Factor Host immune response immunogenic reaction immunological induce Inflammation life-threatening Liposomal clodronate Liposome Macrophage microglia microglial microglial cell Mortality multiorgan failure new SARS-CoV-2 offer pathogenic phagocytic cell pharmacological positive proinflammatory public health reactive reported resulting SARS-CoV-2 infected individuals SARS-COV-2 infection therapeutic strategy variant while [DOI] 10.1016/j.medidd.2022.100136 [Article Type] Review article
SARS-CoV-2 infection- induced growth factors play differential roles in COVID-19 pathogenesisSARS-CoV-2 감염 유발 성장 인자는 COVID-19 발병 기전에서 다른 역할을 합니다Article Published on 2022-09-012022-09-11 Journal: Life sciences [Category] COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, [키워드] adverse effect adverse effects angiopoietin association COVID-19 COVID-19 pathogenesis COVID-19 patient Critical Critically ill cytokine Cytokine storm Cytokine storms Cytokines D-dimer disease dysregulation EGF elevated Endothelial dysfunction EPO erythropoietin exhibited G-CSF growth factor Growth factors HGF Hospitalized ICU Inflammation Injury inverse correlation investigation marker moderate Myoglobin negative correlation non-ICU occur P-selectin Pathogenesis pathogenesis of COVID-19 pathophysiology PDGF plasma positive correlation reflected remained repair SARS-COV-2 infection selectin specific disease Thromboembolism tissue tissue injury Tissue injury. upregulated vague VEGF was performed [DOI] 10.1016/j.lfs.2022.120703 PMC 바로가기 [Article Type] Article
Watch out for neuromyelitis optica spectrum disorder onset or clinical relapse after COVID-19 vaccination: What neurologists need to know?Article Published on 2022-09-012022-11-15 Journal: Multiple sclerosis and related disorders [Category] 진단, [키워드] Adverse adverse effect adverse effects adverse event age Analysis AQP4 article Comorbidity conducted COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines described disease disorder dose EDSS Effectiveness examined female FIVE Frequency impacted inclusion criteria investigated local pain median time Methylprednisolone Mild moderate MOGAD mRNA vaccine nine NMOSD Occurrence Patient patients plasma pulse question reported safety profile SARS-CoV-2 searched severity significantly systematic review the patient therapy Treatment vaccinate vaccination Web of Science [DOI] 10.1016/j.msard.2022.103960 PMC 바로가기
Cataracts in setting of multisystem inflammation after COVID-19 vaccinationCase report Published on 2022-09-012022-10-05 Journal: American Journal of Ophthalmology Case Reports [Category] 진단, [키워드] adverse effect BNT162b2 mRNA Cataract Cataracts coronavirus COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine dose healthy Inflammation male Multisystem inflammatory syndrome-vaccine observation ocular Post-vaccination inflammation raise reported systemic inflammation unique vaccination while widespread with COVID-19 [DOI] 10.1016/j.ajoc.2022.101654 [Article Type] Case report