Luteolin Potentially Treating Prostate Cancer and COVID-19 Analyzed by the Bioinformatics Approach: Clinical Findings and Drug Targets전립선암 및 COVID-19를 잠재적으로 치료하는 루테올린, 생물정보학 접근법으로 분석: 임상 결과 및 약물 표적Endocrinology Published on 2022-02-012022-09-11 Journal: Frontiers in Endocrinology [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, [키워드] Anti-inflammatory effects anticancer bioinformatics characterized clinical clinical feature conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 treatment curative demonstrated Differential gene expression downregulated gene drug drug target Efficiency enhancement enrichment Epidemic evidenced expression finding FOS function Genes Immunity Infection Luteolin malignancies mechanism metabolism molecular docking MPO Mutation network pharmacology Patient patients pharmacological mechanism Prostate cancer RNA sequencing SARS-COV-2 infection signaling pathways target targets the SARS-CoV-2 treating Treatment Vaccine was determined [DOI] 10.3389/fendo.2021.802447 PMC 바로가기 [Article Type] Endocrinology
The Role of Ionizing Radiation for Diagnosis and Treatment against COVID-19: Evidence and ConsiderationsReview Published on 2022-01-292022-10-31 Journal: Cells [Category] COVID-19, SARS, [키워드] alleviate Anti-inflammatory effects anti-inflammatory treatment Cancer cardiac disease Chest CT Clinical use Computed tomography Coronavirus disease 2019 COVID-19 COVID-19 patient deaths decrease diagnostic effective Evidence health worker healthcare identify imaging ionizing radiation life-threatening low dose low dose radiation therapy (LDRT) management pandemic patients Pneumonia Radiation radiation therapy Radiotherapy risk role Spread Symptom the disease treat Treatment [DOI] 10.3390/cells11030467 PMC 바로가기 [Article Type] Review
Yindan Jiedu granules exhibit anti-inflammatory effect in patients with novel Coronavirus disease (COVID-19) by suppressing the NF-κB signaling pathwayYindan Jiedu 과립은 NF-κB 신호 전달 경로를 억제하여 신종 코로나바이러스 감염증(COVID-19) 환자에서 항염증 효과를 나타냅니다.Randomized Controlled Trial Published on 2022-01-012022-09-11 Journal: Phytomedicine : international journal of phytother [Category] SARS, 유전자 메커니즘, 임상, [키워드] accompanied Activation acute lung injury amyloid A Analysis animals anti-inflammatory effect Anti-inflammatory effects assigned caused CD4 cells clinical Clinical research Compound compounds control group coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 progression Cytokines death decrease disease dissipation docking Effect enrichment analysis erythrocyte sedimentation erythrocyte sedimentation rate evaluate evaluated Factor Granule high-performance liquid chromatography histological HPLC IL-1β IL-6 immune in vitro increase in Inflammation Inflammatory Inflammatory cytokine Inflammatory cytokines inflammatory factors inhibit inhibiting Interaction IκBα kaempferol lesion Ligand ligands lipopolysaccharide lung Lung injury Luteolin mass spectrometry mechanism mechanism of action molecular docking Negative conversion network model NF-κB NF-κB pathway NF-κB signaling NF-κB signaling pathway nuclear translocation nucleic acid overlapping p65 pandemic participant pathway Patient Pharmacology Pharmacology analysis Phosphorylation progression propensity score matching PSM quercetin Randomly recruited sedimentation rate serum serum amyloid significantly strong interaction suppressed T cell Tandem mass spectrometry target targets therapeutic effect therapeutic effects TNF-α viral nucleic acid were measured Yindan jiedugranules. [DOI] 10.1016/j.phymed.2021.153784 PMC 바로가기 [Article Type] Randomized Controlled Trial
The Possible Role of Bruton Tyrosine Kinase Inhibitors in the Treatment of COVID-19: A ReviewReview article Published on 2021-12-152022-10-05 Journal: Current Therapeutic Research [Category] 바이오마커, 변종, 치료법, [키워드] anti-inflammatory cytokines Anti-inflammatory effects Bruton tyrosine kinase inhibitor BTK BTK inhibitor caused Clin clinician Complication Coronavirus disease 2019 COVID-19 cytokine level Cytokine release syndrome Cytokines develop disease Effect Effectiveness Elsevier evaluate Exp immune response Inflammation Inflammatory cytokines information journal kinase less management medication Mortality Novel coronavirus objective pandemic Pathogenesis pathogenesis of COVID-19 pathway Patient patients patients with COVID-19 provide receiving reduce Result review role SARS-CoV-2 Serum level Severe case severe respiratory illness Signaling Spread subsequent Support the disease treating COVID-19 Treatment tyrosine Web of Science [DOI] 10.1016/j.curtheres.2021.100658 [Article Type] Review article
Niclosamide for Covid-19: bridging the gapCovid-19용 니클로사미드: 격차 해소Review Published on 2021-12-012022-09-11 Journal: Molecular biology reports [Category] SARS, 치료제, [키워드] acute respiratory distress syndrome angiotensin Angiotensin-converting enzyme anthelminthic Anti-inflammatory anti-inflammatory effect Anti-inflammatory effects anti-SARS-CoV-2 Antiviral antiviral activities Antiviral effect antiviral effects biological processes clinical outcomes clinical study clinical trial clinical trials Concentration concerning COVID-19 COVID-19 severity Cytokines Cytopathic effect Direct disease distress Effect endosomal pH enzyme Google Scholar homeostasis immune in vivo Inflammasome inflammatory signaling inhibit interruption mandatory maturation mechanism modulate modulating mTOR mTOR signaling NCL neutralization NF-κB niclosamide NLRP3 NLRP3 inflammasome oral bioavailability oxidative phosphorylation pandemic pathway Patient pleiotropic pro-inflammatory cytokines Prospective protective role reduce reducing Regulatory respiratory distress Respiratory distress syndrome SARS-CoV-2 SARS-COV-2 infection Science Science Direct serum severity signaling pathway suppression therapeutic therapy treat viral proliferation Viral protein was done Web of Science [DOI] 10.1007/s11033-021-06770-7 PMC 바로가기 [Article Type] Review
Fluvoxamine for the Early Treatment of SARS-CoV-2 Infection: A Review of Current EvidenceSARS-CoV-2 감염의 조기 치료를 위한 Fluvoxamine: 현재 증거 검토Review Published on 2021-12-012022-09-11 Journal: Drugs [Category] SARS, 비임상, 임상, [키워드] anti-inflammatory effect Anti-inflammatory effects appear available data breath Canada cause Clinical deterioration clinician condition controlled trials COVID-19 COVID-19 pandemic COVID-19 treatment COVID-19 treatment guidelines current cytokine production Decision making Dosing early treatment Efficacy fluvoxamine Infection inhibitor investigators knowledge long-lasting mechanism medication meeting morbidity morbidity and mortality NIH observational study potential mechanism potential mechanisms Psychiatric randomized clinical trial Randomized controlled trial receptor reduce Research review Safe SARS-CoV-2 SARS-COV-2 infection selective Sepsis Serotonin Treatment Trial USA [DOI] 10.1007/s40265-021-01636-5 PMC 바로가기 [Article Type] Review
Whole-lung low-dose radiation therapy (LD-RT) for non-intubated oxygen-dependent patients with COVID-19-related pneumonia receiving dexamethasone and/or remdesevir덱사메타손 및/또는 렘데세비르를 투여받는 COVID-19 관련 폐렴이 있는 삽관되지 않은 산소 의존 환자를 위한 전폐 저선량 방사선 요법(LD-RT)Article Published on 2021-12-012022-09-11 Journal: Radiotherapy and oncology : journal of the Europea [Category] SARS, 바이오마커, 비임상, 치료기술, [키워드] Adding addition Analysis animal model anti-inflammatory effect Anti-inflammatory effects Biomarkers biomarkers of inflammation breath C-reactive protein cardiac injury clinical clinical recovery Cohort Control controls COVID-19 COVID-19 patient creatine creatine kinase CRP declined Dexamethasone drug therapy drug treatment drug treatments febrile Hospitalization Inflammation Injury intubation Intubation rates low-dose Low-dose radiation Non-intubated outcome oxygen Oxygenation Patient patients evaluated Pneumonia predicted Predictive produced Prospective trial radiation therapy Radiographic Radiotherapy randomized trial receiving reduced reduction reduction in Significant significant differences subset survival therapy treated Treatment Trial [DOI] 10.1016/j.radonc.2021.10.003 PMC 바로가기 [Article Type] Article
Protective potential of high-intensity interval training on cardiac structure and function after COVID-19: protocol and statistical analysis plan for an investigator-blinded randomised controlled trialCOVID-19 이후 심장 구조 및 기능에 대한 고강도 인터벌 트레이닝의 보호 가능성: 조사자 맹검 무작위 대조 시험을 위한 프로토콜 및 통계 분석 계획Article Published on 2021-11-182022-09-11 Journal: BMJ Open [Category] SARS, 임상, [키워드] 1:1 Anti-inflammatory effects approved Capital Capital Region cardiac injury cardiac mass Cardiology Cardiopulmonary cardiorespiratory cardiorespiratory fitness changes in Committee control group COVID-19 Denmark discharged Ethics hospital Hypothesis hypothesise hypothesised IMPROVE Inconclusive Injury interval training Intervention life Lung function morbidity peer-reviewed positive protocol Quality of life randomised randomised controlled trial reduce reducing Region Registered registration number Safe Sex Sports Medicine standard care Statistical analysis plan survivor Symptom systemic inflammatory response Trial Registration Number [DOI] 10.1136/bmjopen-2020-048281 PMC 바로가기 [Article Type] Article
Update on Intravenous Immunoglobulin in Neurology: Modulating Neuro-autoimmunity, Evolving Factors on Efficacy and Dosing and Challenges on Stopping Chronic IVIg TherapyCurrent Perspectives Published on 2021-11-112022-10-30 Journal: Neurotherapeutics : the journal of the American So [Category] Coronavirus, MERS, SARS, [키워드] Activation addressed affecting Anti-inflammatory effects anti-SARS-CoV-2 antibodies antibody antigenic peptides approved autoantibodies Autoimmune challenge chronic complement conditions conserved cross-react Cytokines Dosing Effect effective Efficacy Encephalitis epilepsy Evidence exhibit Express Factor fatigue FcγRIIb genes encoding Genetic healthy donors Humoral immunity IgG IgG1 Immunomodulation by IVIg Inflammatory mediators infused Initiating and stopping IVIg Intravenous immunoglobulin isotype IVIG IVIg and IgG4 neuro-autoimmunities MMN neurological Neurological disorders neurological sign neuronal pathogenic autoantibody Patient polymorphism positive Protein Randomized controlled trials recent receptors sera stability Stopping Symptom therapy Treatment weakness worsening [DOI] 10.1007/s13311-021-01108-4 PMC 바로가기 [Article Type] Current Perspectives
The Role of an Anti-Inflammatory Diet in Conjunction to COVID-19Review Published on 2021-10-292022-11-01 Journal: Diseases [Category] COVID-19, [키워드] acute respiratory syndrome Anti-inflammatory anti-inflammatory diet Anti-inflammatory effects approach chemokines component conjunction Coronavirus-2 COVID-19 COVID-19 and diet COVID-19 patient Cytokine release syndrome diet dietary supplement Effects fatty acids Healthcare system immune system International investigated nutrition nutritional status omega-3 Patient Prevent Proinflammatory cytokine Research role SARS-CoV-2 severity shown suppresse systemic inflammatory response the disease Vitamin C [DOI] 10.3390/diseases9040076 PMC 바로가기 [Article Type] Review