Fluoxetine as an anti-inflammatory therapy in SARS-CoV-2 infection
SARS-CoV-2 감염에서 항염증제로서의 Fluoxetine
Article
[키워드] activated
acute respiratory syndrome
acute respiratory syndrome coronavirus
Admission
Anti-inflammatory effects
Anti-inflammatory therapy
antidepressants
Asthma
B cell
caused
cell line
cell lines
Clinical outcome
complex
coronavirus
coronavirus 2
coronavirus disease
Coronavirus disease 2019
COVID-19
Critical
Cytokine IL6
Cytokine storm
disease
downstream
drug
Fluoxetine
gp130
Hyperinflammatory response
hyperinflammatory state
identify
IL6
IL6R
IL6ST
increase
Infection
Inflammation
inflammatory pathways
intensive care
intensive care unit admission
interact
interleukin 6
knockdown
mechanism
Mortality
NF-κB
NFkB1
nuclear
Nuclear factor kappa B subunit 1
Organ failure
Patient
potential therapy
Protein
receptor
regulate
respiratory
SARS-CoV-2
SARS-COV-2 infection
Selective serotonin reuptake inhibitors
Sepsis
Serotonin
severe acute respiratory syndrome Coronavirus
severe acute respiratory syndrome coronavirus 2
Signal transduction
SSRIs
subunit
suppressed
target gene
transcription factor
Transcription factor NF-κB.
transcriptomic
variety
[DOI] 10.1016/j.biopha.2021.111437 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.biopha.2021.111437 PMC 바로가기 [Article Type] Article