Synthetic, biological and optoelectronic properties of phenoxazine and its derivatives: a state of the art reviewShort Review Published on 2023-02-092024-09-05 Journal: Molecular diversity [Category] update2024, [키워드] Actinomycin D antimalarial Antiviral Fluorescent probe Phenoxazine [DOI] 10.1007/s11030-023-10619-5 PMC 바로가기 [Article Type] Short Review
Evaluation of Pharmacokinetics, Biodistribution, and Antimalarial Efficacy of Artemether-Loaded Polymeric NanorodsArticle Published on 2023-01-022024-08-29 Journal: Molecular Pharmaceutics [Category] 말라리아, [키워드] antimalarial Artemether nanoprecipitation Nanorods Plasmodium berghei poly(lactic-co-glycolic) acid polymeric nanoparticles.
Evaluation of ferrocenyl-containing γ-hydroxy-γ-lactam-derived tetramates as potential antiplasmodialsarticle Published on 2022-12-312024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] antimalarial Fenton Ferrocene lactam ROS Tetramate [Article Type] article
Structural-activity Relationship of Metallo-aminoquines as Next Generation Antimalarialsarticle Published on 2022-12-312024-09-01 Journal: Current Topics in Medicinal Chemistry [Category] 말라리아, [키워드] Aminoquinolines antimalarial Chloroquine cytotoxicity Ferroquine in vitro in vivo β-hematin inhibition [Article Type] article
Targeting Artemisinin-Resistant Malaria by Repurposing the Anti-Hepatitis C Virus Drug AlisporivirArticle Published on 2022-12-202024-08-29 Journal: Med Instrum [Category] 말라리아, [키워드] alisporivir antimalarial Artemisinin resistance cyclosporin A PfCyclophilin 19B
In silico validation of novel inhibitors of malarial aspartyl protease, plasmepsin V and antimalarial efficacy predictionArticle Published on 2022-11-302024-09-10 Journal: J Biomol Struct Dyn [Category] 말라리아, [키워드] antimalarial drug design in silico Plasmepsin PMC 바로가기
Virtual screening of quinoline derived library for SARS-COV-2 targeting viral entry and replicationArticle Published on 2022-11-012022-11-15 Journal: Journal of biomolecular structure & dynamics [Category] SARS, 치료제, [키워드] added antibiotic antimalarial Antiviral approved binding domain Bruton tyrosine kinase inhibitors China claimed contagious Control country COVID-19 pandemic Dependent disease domain drug drug design FDA in viral in-depth analysis increase Infection inhibiting inhibitor Interaction interfere M pro MD simulation number of infected outbreak Papain Population protease provide Psychological distress quinoline based FDA approved Drugs. RBD Remdesivir Replication required resource RNA RNA dependent RNA polymerase RNA polymerase RNA virus SARS-CoV-2 selected Spike protein spread to target Vaccines viral entry viral replication Virtual screening [DOI] 10.1080/07391102.2021.1913228 PMC 바로가기
Computational and experimental insights on the interaction of artemisinin, dihydroartemisinin and chloroquine with SARS-CoV-2 spike protein receptor-binding domain (RBD)Article Published on 2022-10-012022-11-15 Journal: Natural Product Research [Category] COVID19(2023년), SARS, 치료제, [키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 antimalarial Antiviral agents Artemisinin bind bio-layer interferometry Chloroquine complexes Compound computational tool Coronavirus disease-19 Coronavirus-2 COVID-19 demonstrated derivative docking study domain drug candidate host cell in vitro Interaction interfere Invasion investigated mechanism mechanisms metabolite molecular molecular dynamics predicted Protein RBD SARS-CoV-2 SARS-CoV-2 spike protein small molecule Spike protein stability treat [DOI] 10.1080/14786419.2021.1925894 PMC 바로가기
Designing and development of phthalimides as potent anti-tubulin hybrid molecules against malariaarticle Published on 2022-09-302024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] antimalarial Drug discovery drug resistance Phthalimide analogs Plasmodium falciparum tubulin [Article Type] article
In vitro and in silico assessment of new beta amino ketones with antiplasmodial activity항말라리아 활성을 가진 새로운 베타 아미노 케톤의 인 비트로 및 인 실리코 평가Article Published on 2022-09-262024-08-26 Journal: Revista da Sociedade Brasileira de Medicina Tropical [Category] 말라리아, [키워드] antimalarial Chemotherapy docking malaria [DOI] 10.1590/0037-8682-0590-2022 PMC 바로가기