Sa1000: DIARRHEA, ELEVATED AST, AND ELEVATION OF INFLAMMATORYRELATED BIOMARKERS IS A PREDICTOR FOR MORTALITY IN MINORITY HOSPITALISED COVID-19 PATIENTSConference abstract Published on 2022-05-012022-10-05 Journal: Gastroenterology [Category] 바이오마커, [키워드] AST COVID-19 [DOI] 10.1016/S0016-5085(22)60661-9 [Article Type] Conference abstract
Genetic Sequence of Coronavirus Strains Isolated from Iraqi Patients and their Relationship with some Liver Enzymes and InterleukinsArticle Published on 2022-04-302022-11-15 Journal: Archives of Razi Institute [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome Admission Alpha ALT assigned AST asymptomatic patients Baghdad blood sample cause caused characterized coronavirus coronavirus disease correlation COVID-19 Deceased disease severity enzyme faster five group Genetic Genetic sequence genus Betacoronavirus groups hospitalized patient Il -10 Il- 18 IL-10 IL-18 Illumina indicated intensive care units interleukin Iraq isolate Isolated isolation hospital lactate dehydrogenase LDH less liver enzyme Ministry of Health moderate nasopharyngeal outcome polymerase chain positive sample positive-sense single-stranded RNA Public Quantitative relationship RT-PCR SARS-CoV-2 sequence severe symptom significantly Spread statistically significant strain TNF- α venous virulence virulent virus was determined WHO World Health Organization Wuhan Wuhan strain [DOI] 10.22092/ARI.2022.357089.1967 PMC 바로가기
Liver Injury in COVID-19 Patients with Drugs as Causatives: A Systematic Review of 996 DILI Cases Published 2020/2021 Based on RUCAM as Causality Assessment Method약물을 원인으로 하는 COVID-19 환자의 간 손상: 인과 평가 방법으로 RUCAM을 기반으로 2020/2021 게시된 996개의 DILI 사례에 대한 체계적인 검토Review Published on 2022-04-272022-09-11 Journal: International Journal of Molecular Sciences [Category] 치료제, [키워드] Abnormalities abnormality Alanine alanine aminotransferase Algorithm ALT ALT/AST antiviral drug antiviral drugs aspartate Aspartate aminotransferase assessment AST Causality caused Characteristics China Clinical characteristics clinical feature Clinical features confounders confounding variable coronavirus disease country COVID-19 COVID-19 case COVID-19 patient COVID-19 patients defined Diagnosis diagnostic DILI drug drug treatment Drug-induced liver injury drug-induced liver injury. Established diagnosis feature female hepatocellular injury India Japan Liver disease liver diseases Liver injury liver test Liver tests male median age Montenegro Most patients outcome patients patients treated provided ranged reported review robust Roussel Uclaf Causality Assessment Method RUCAM searched Spain systematic review the mean therapeutic efficacy Treatment Undetermined virus [DOI] 10.3390/ijms23094828 PMC 바로가기 [Article Type] Review
Laboratory Biomarkers for Diagnosis and Prognosis in COVID-19COVID-19 진단 및 예후를 위한 실험실 바이오마커Review Published on 2022-04-272022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, [키워드] Admission Analysis aspartate Aspartate transaminase AST Biomarker Biomarkers BNP Brain brain natriuretic peptide cause clinical manifestations Clinical practice coronavirus disease Coronavirus disease 2019 COVID-19 creatine creatine kinase Cytokines D-dimer Diagnosis diagnostic disease severity focus Future Hospitalization ICU identify include Inflammation intensive care intensive care unit laboratory biomarker laboratory biomarkers Lactate lactate dehydrogenase LDH Lymphocytes metabolomic metabolomics Mortality multiorgan failure Myoglobin N-terminal Neuron-specific enolase neutrophil neutrophil count Neutrophils NT-proBNP outcome outcomes peptide predict Prognosis Prognostic value progression proinflammatory cytokines proteomic proteomics Research respiratory risk stratification SARS-CoV-2 Severe acute respiratory syndrome severe cases severe COVID-19 shown translated [DOI] 10.3389/fimmu.2022.857573 PMC 바로가기 [Article Type] Review
Longitudinal relationship of liver injury with inflammation biomarkers in COVID-19 hospitalized patients using a joint modeling approach공동 모델링 접근법을 사용하는 COVID-19 입원 환자의 염증 바이오마커와 간 손상의 종단 관계Article Published on 2022-04-012022-09-11 Journal: Scientific Reports [Category] 바이오마커, 치료법, 치료제, [키워드] age Alanine Alanine transaminase alkaline phosphatase ALT approach aspartate Aspartate transaminase AST Biomarker blood lymphocyte count C-reactive protein change consecutive patient correlated correlation COVID-19 COVID-19 infection CRP D-dimer decrease died evaluate Generalized hospital Hospitalization hospitalized patient Inflammation inflammation marker inflammation markers interleukin interleukin-6 joint Liver damage Liver disease Liver injury longitudinal lymphocyte Lymphocyte count marker mechanism negative correlation Patient patients with COVID-19 phosphatase plasma positive serum serum C-reactive protein Sex Spain statistical survival Survivors systemic inflammation the patient therapy was used were used [DOI] 10.1038/s41598-022-09290-x PMC 바로가기 [Article Type] Article
High Serum Progranulin Levels in COVID-19 Patients: A Pilot StudyCOVID-19 환자의 높은 혈청 프로그래뉼린 수치: 파일럿 연구Article Published on 2022-03-012022-09-11 Journal: Biochemistry. Biokhimiia [Category] MERS, 바이오마커, [키워드] All participants ALT AST Asymptomatic AUC Biomarker can be used Concentration control group Course COVID-19 COVID-19 disease CRP determinant determine Diagnosis ELISA kits evaluate examined healthy individual healthy individuals IL-6 infected with COVID-19 Level moderate participant Patient patients PCT predict Prognosis progranulin ROC analysis serum severity statistically the disease the patient TNF-α was performed WBC were measured [DOI] 10.1134/S0006297922030026 PMC 바로가기 [Article Type] Article
Abnormal liver chemistries as a predictor of COVID-19 severity and clinical outcomes in hospitalized patientsObservational Study Published on 2022-02-072022-10-04 Journal: World journal of gastroenterology [Category] 임상, [키워드] abnormality acute respiratory syndrome adjusted Admission alanine aminotransferase albumin level alkaline phosphatase ALP ALT Asian Aspartate aminotransferase association AST Baltimore Bilirubin bilirubin. can be used Clinical characteristics Clinical outcome collected coronavirus COVID-19 COVID-19 patient COVID-19 severity Cox regression Cox regression analysis demographic disease severity drugs elevated Factor highest Hospital admission Hospitalization Hospitalized hospitalized patient in-hospital mortality Johns Hopkin Laboratory liver Liver injury Liver tests Measures mechanical ventilation mortality risk obesity Older age Other outcome Patient patients patients with COVID-19 predict Prevalence prevalent Prognosis retrospective risk serum severe acute respiratory syndrome coronavirus 2 severity severity and prognosis severity of COVID-19 System the patient therapy total bilirubin Treatment United States variable was used with COVID-19 [DOI] 10.3748/wjg.v28.i5.570 PMC 바로가기 [Article Type] Observational Study
Continuous Renal Replacement Therapy With oXiris Filter May Not be an Effective Resolution to Alleviate Cytokine Release Syndrome in Non-AKI Patients With Severe and Critical COVID-19Pharmacology Published on 2022-02-042022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Admission alanine aminotransferase ALB albumin alleviate ALT Aspartate aminotransferase AST C-reactive protein circulating cytokine clinical collected Concentration Continuous Continuous renal replacement therapy control group coronavirus disease COVID-19 Critical CRP CRRT CRS Cytokine release syndrome Cytokine storm demographic determine fibrinogen Filter hospital Hospitalization hyper inflammation ICU IFN-γ IL-10 IL-2 IL-4 IL-6 individual inflammatory chemokines intervention group IRB lymphocyte Lymphocyte count medical records medical system neutrophil no significant difference non-acute kidney injury Organ failure oXiris filter Patient Platelet proportion Protein random number table randomly divided Release renal replacement therapy replacement Resolution SARS-COV-2 infection sensitivity serum creatinine severe and critical COVID-19 severity of COVID-19 significantly significantly higher significantly lower SOFA strained TNF-α total bilirubin treated Treatment two groups WBC White blood cell [DOI] 10.3389/fphar.2022.817793 PMC 바로가기 [Article Type] Pharmacology
Implications of SARS-CoV-2 infection on the clinical, hematological, and inflammatory parameters in COVID-19 patients: A retrospective cross-sectional studySARS-CoV-2 감염이 COVID-19 환자의 임상, 혈액학 및 염증 매개변수에 미치는 영향: 후향적 횡단면 연구Article Published on 2022-02-012022-09-11 Journal: Journal of infection and public health [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] acute respiratory distress acute respiratory syndrome Admission age Analysis AST Atypical Atypical pneumonia bacterial and fungal infections baseline data biological markers Biomarker caused characteristic characterized clinical clinical laboratory Clinical parameters Clinical predictors Coagulation colds Comorbidities coronavirus COVID COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity creatine creatinine cross-sectional study CRP D-dimer determine examined ferritin FIVE fungal infections group groups help hematologic hematological hematological parameters highest illnesses Inflammatory biomarker inflammatory biomarkers Inflammatory marker inflammatory markers inflammatory parameter intensive care laboratory data laboratory parameter Laboratory parameters liver liver biomarkers medications Mild Most patients not differ operator Organ failure pandemic parameter Patient patient groups patients Pneumonia predictor procalcitonin receiver Receiver operator characteristic regulated Regulation renal function respiratory respiratory distress Retrospective cross-sectional study ROC ROC analysis SARS CoV SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection secondary bacterial severe acute respiratory syndrome virus severity severity of COVID-19 Sex significant difference significant differences significantly the disease the patient threshold thrombosis Validity virus was used WBC [DOI] 10.1016/j.jiph.2021.12.013 PMC 바로가기 [Article Type] Article
Clinical features, management, and outcome of hemodialysis patients with SARS-CoV-2SARS-CoV-2 혈액투석 환자의 임상 양상, 관리 및 결과Article Published on 2022-02-012022-09-11 Journal: Therapeutic apheresis and dialysis : official peer [Category] COVID19(2023년), SARS, 바이오마커, [키워드] Adult age AST Chest CT chronic renal failure clinical clinical feature Clinical features clinical manifestations Clinical outcome Comorbidity COVID-19 COVID-19 infection CRP level CRP levels cure demographic determine diagnosed died discharged Dyspnea enrolled eosinophil eosinophil counts evaluate evaluated fatigue feature Features Hemodialysis intensive care intensive care unit laboratory data lesion management Mortality mortality rate Older Older age outcome Patient patients patients died patients with SARS-CoV-2 Platelet Potassium prognostic Prognostic factors Prospective Study renal renal failure risk factor SARS-CoV-2 Seven single-center survived Symptom the patient transferred troponin two group two groups with COVID-19 [DOI] 10.1111/1744-9987.13696 PMC 바로가기 [Article Type] Article