Modelling the interplay of SARS-CoV-2 variants in the United Kingdom영국에서 SARS-CoV-2 변종 상호작용 모델링Article Published on 2022-07-202022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] affecting appearance applied available data compartmental model country COVID-19 COVID-19 vaccine delta variant determine Effect effective favor feature geographical distribution help include infections key factor measure pandemic parameter Prevalence prevalent Prevent recurrence SARS-CoV-2 variant severe disease Spread strain Stress the disease United Kingdom vaccination Vaccination strategies variants variants of concern [DOI] 10.1038/s41598-022-16147-w PMC 바로가기 [Article Type] Article
Multi-Faceted Analysis of COVID-19 Epidemic in Korea Considering Omicron Variant: Mathematical Modeling-Based Study오미크론 변이를 고려한 국내 코로나19 다면 분석: 수학적 모델링 기반 연구Article Published on 2022-07-042022-09-11 Journal: Journal of Korean medical science [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] Administered age Analysis antiviral drug antiviral drugs available data average B.1.1.529 booster Border caused Community COVID-19 Effectiveness Endemic examined exceeded Factors force force of infection Formula group Hospital stay incidence influx intensity Intervention likelihood mathematical mathematical model mathematical modeling maximum likelihood estimation measure Nonpharmaceutical interventions NPI NPIs omicron Omicron variant Omicron Variant, Nonpharmaceutical Interventions parameter quantified ranged reduced representing Severe case severe cases Severity rate social distancing Spread the epidemic the timing Transmission transmission rate transmission rates vaccination Vaccine variant was performed [DOI] 10.3346/jkms.2022.37.e209 PMC 바로가기 [Article Type] Article
Hybrid immunity against COVID-19 in different countries with a special emphasis on the Indian scenario during the Omicron period오미크론 기간 동안 인도 시나리오에 특히 중점을 둔 여러 국가의 COVID-19에 대한 하이브리드 면역Article Published on 2022-07-012022-09-11 Journal: International immunopharmacology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Antibody Response available data country COVID-19 COVID-19 vaccine cumulative cumulative effect described dose herd immunity hybrid Hybrid immunity Immunity India individual infected individual Infection less molecular basis omicron produced provide robust SARS-CoV-2 SARS-CoV-2 variants scientist the disease the vaccine Third wave in India. Vaccine virus [DOI] 10.1016/j.intimp.2022.108766 PMC 바로가기 [Article Type] Article
Tumor marker response to SARS-CoV-2 infection among patients with cancer암 환자의 SARS-CoV-2 감염에 대한 종양 표지자 반응Article Published on 2022-07-012022-09-11 Journal: Cancer Medicine [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] Antigen available data Cancer cancer diagnosis Cancer management cancer patient Cancer patients cancer progression carbohydrate Carcinoembryonic antigen Case series case sery CEA clinical Clinical data Clinical management clinical observations condition conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection demographics Diagnosis Electronic health record Elevation Evidence evidence of Health health record implication induce Infection Inflammatory response Inflammatory responses knowledge Laboratory Laboratory test malignancy marker occurred Patient patients Patients with cancer patients with COVID-19 PCR test positive SARS-CoV-2 PCR positive SARS-CoV-2 PCR test Post-infection Research respiratory Respiratory Coronavirus response resulting SARS-CoV-2 SARS-COV-2 infection severe acute respiratory coronavirus severity of COVID-19 solid tumor Treatment Tumor tumor marker tumor markers Viral viral infection [DOI] 10.1002/cam4.4646 PMC 바로가기 [Article Type] Article
Acceptability and feasibility of leveraging community-based HIV counselling and testing platforms for same-day oral PrEP initiation among adolescent girls and young women in Eastern Cape, South Africa남아프리카 공화국 이스턴 케이프의 청소년 소녀와 젊은 여성을 대상으로 당일 구두 PrEP 시작을 위한 커뮤니티 기반 HIV 상담 및 테스트 플랫폼 활용의 수용 가능성 및 타당성Article Published on 2022-07-012022-09-11 Journal: Journal of the International AIDS Society [Category] 치료제, [키워드] acceptability acquisition adolescent girls and young women African available data baseline Cape Care cohort characteristics community-based HIV testing Complete COVID-19 pandemic Descriptive statistics detectable differentiated care. eligibility facilitate feasibility Health high risk HIV HIV prevention HIV testing HIV-negative Infection initiated integration measure medication platform post-hoc PrEP Prevalence Prophylaxis proportion questionnaire reported required risk Risk assessment sexually transmitted infection South South Africa study participant tent tested transmitted were measured women [DOI] 10.1002/jia2.25968 PMC 바로가기 [Article Type] Article
Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis2021년 11월 14일까지 SARS-CoV-2의 전 세계, 지역 및 국가 일일 및 누적 감염 추정: 통계 분석Article Published on 2022-06-252022-09-11 Journal: Lancet (London, England) [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] accounted adjusted Analysis antibody approach Asia assumption available data B.1.1.529 Baltimore calculated Complete country COVID-19 COVID-19 research cumulative database death deaths determinant determinants distribution effective estimate excess mortality foundation future infection help herd immunity Herd immunity threshold highest Hospital admissions hospitalisation hospitalisations identify IFR IHR Immunity India individual individuals Infection infection rate infection rates infections infectious infectiousness information Johns Hopkins Johns Hopkins University location lowest Melinda Gate Melinda Gates Mortality National occurred Oceania pandemic parameter peaking per day Population predict predictor produced proportion Reinfection reported Reporting reproductive responses risk robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections sensitivity seroprevalence survey Seven statistical statistical analysis statistical model sub-Saharan Africa susceptibility systematic reviews These data transmission patterns USA Vaccinations Vaccine variant variants [DOI] 10.1016/S0140-6736(22)00484-6 PMC 바로가기 [Article Type] Article
Risks of SARS-CoV-2 Infection and Immune Response to COVID-19 Vaccines in Patients With Inflammatory Bowel Disease: Current Evidence염증성 장 질환 환자의 코로나19 백신에 대한 SARS-CoV-2 감염 및 면역 반응의 위험: 현재 증거Review Published on 2022-06-232022-09-11 Journal: Frontiers in Immunology [Category] 변종, [키워드] aberrant immune response Affect available data bowel Combination condition Corticosteroid Corticosteroids Course COVID-19 COVID-19 vaccine COVID-19 vaccines Crohn's disease Crohn’s disease current disease dysregulated environmental factors Factor forms healthy subjects IBD immune immune response immunogenicity Immunosuppressant immunosuppressants increased risk infection with SARS-CoV-2 infections Inflammatory Inflammatory bowel disease inflammatory bowel diseases intestinal intestinal disease less majority many case many cases measure modify Necrosis occur pandemic Pathogens Patient patients treated PROTECT Psychological psychological factors question receive reduce reduced response risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants significantly increased subject susceptibility susceptibility to infection susceptible individual therapy ulcerative colitis Vaccine [DOI] 10.3389/fimmu.2022.933774 PMC 바로가기 [Article Type] Review
Artificial intelligence and machine learning approaches for drug design: challenges and opportunities for the pharmaceutical industries약물 설계를 위한 인공 지능 및 기계 학습 접근 방식: 제약 산업의 도전과 기회Review Published on 2022-06-012022-09-11 Journal: Molecular diversity [Category] 신약개발, [키워드] addition applied artificial artificial intelligence available data clinical clinical trial clinical trials compounds computer-aided drug design costly Critical critical point decrease deep deep learning Developing disease drug design drug target drugs imaging information intractable machine machine learning machine learning approach momentum overcome pharmaceutical industry Pharmaceutical industry. raised Research resource spread of COVID-19 step Trial Virtual screening [DOI] 10.1007/s11030-021-10326-z PMC 바로가기 [Article Type] Review
Post-COVID-19 syndrome, low-grade inflammation and inflammatory markers: a cross-sectional studyPost-COVID-19 증후군, 저등급 염증 및 염증 표지자: 단면 연구Article Published on 2022-06-012022-09-11 Journal: Current medical research and opinion [Category] MERS, 바이오마커, [키워드] acute COVID-19 acute phase affected age Ageusia analysed Analysis Anosmia association available data best Biomarker Biomarkers BMI C-reactive protein collected Community community setting Comorbidities correlation COVID-19 COVID-19 case cross-sectional cross-sectional study CRP D-dimer level D-dimer levels defined develop distributions Dyspnea Elevation epidemiological data fatigue ferritin fibrinogen Fibrinogen levels Frequency highest identify increased risk Infection Inflammatory inflammatory markers Laboratory Laboratory test Lactate lactate dehydrogenase low-grade inflammation lymphocyte lymphocyte counts marker men Mild mild COVID-19. multivariable analysis multivariate multivariate analyses myalgia neutrophil neutrophil count neutrophil counts neutrophil/lymphocyte ratio NLR pathophysiological mechanism performed post-COVID syndrome prevalent reported symptom selected serum C-reactive protein Sex Sex difference Signs and symptoms smoking subject Symptom Symptoms syndrome the median variable with COVID-19 woman women [DOI] 10.1080/03007995.2022.2042991 PMC 바로가기 [Article Type] Article
Single-cell transcriptome profiling of the immune space-time landscape reveals dendritic cell regulatory program in polymicrobial sepsis면역 시공간 환경의 단일 세포 전사체 프로파일링은 다균성 패혈증에서 수지상 세포 조절 프로그램을 보여줍니다Article Published on 2022-05-292022-09-11 Journal: Theranostics [Category] 치료제, [키워드] activated adopted alteration Analysis applied available data Cancer canonical CD4 cDCs characterized co-cultured comprehensive view conserved COVID-19 patients Cytometry demonstrated dendritic dendritic cell dendritic cells described determined by dissect experiment experiments expression Flow flow cytometry generate Genes heterogeneity Host immune response hyperinflammation identify IFNGR2 immune Immune cell immune cell types immune cells immunofluorescence Immunosuppression indicated inhibitory initiated Intracellular majority maturation morbidity multiplex immunofluorescence myeloid cells naïve natural killer observation organ dysfunction pathway Pathways progression promoted protein level Puncture rationale Regulatory regulatory T cells reveal scRNA-seq ScRNA-seq analysis Sepsis septic septic patients signaling pathway single-cell single-cell analysis Single-cell RNA sequencing specific type staining STAT3 subset T cell T cells tissue tissue sites Transcriptome unique upregulation [DOI] 10.7150/thno.72760 PMC 바로가기 [Article Type] Article