Characterization of Entry Pathways, Species-Specific Angiotensin-Converting Enzyme 2 Residues Determining Entry, and Antibody Neutralization Evasion of Omicron BA.1, BA.1.1, BA.2, and BA.3 VariantsArticle Published on 2022-09-142022-11-15 Journal: Journal of Virology [Category] SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] ACE2 ACE2 receptor addition angiotensin-converting enzyme 2 animal ACE2 receptors antibody breakthrough infections Cell characterization Chloroquine D614G D614G variant Determining dose elicit endosomal entry ENhance exhibit greater groups immune evasion Infection inhibitor less Lineage mechanism mRNA vaccination mRNA vaccine neutralization neutralization resistance neutralization titer Neutralizing antibodies neutralizing antibody omicron Pathways pseudovirus public health SARS-CoV-2 SARS-CoV-2 Omicron variants sensitivity spike mutation Spread Substitution substitutions tested TMPRSS2 transmembrane serine protease transmembrane serine protease 2 Transmissibility Transmission vaccination Vaccine vaccine booster variant variants virus entry virus entry pathways. zoonotic [DOI] 10.1128/jvi.01140-22 PMC 바로가기
Effects of SARS-CoV-2 Alpha, Beta, and Delta variants, age, vaccination, and prior infection on infectiousness of SARS-CoV-2 infectionsArticle Published on 2022-09-132022-11-16 Journal: Frontiers in Immunology [Category] SARS, 변종, [키워드] age Analysis association Beta Breakthrough infection breakthrough infections children conducted COVID-19 cycle threshold declined Delta demonstrated Effect Epidemiology highest Immunity incidence increase individual individuals Infection infections investigated lowest PCR random Regression Reinfection SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant Sex Symptom tested Travel vaccination Vaccine vaccine doses variant variants [DOI] 10.3389/fimmu.2022.984784 PMC 바로가기
Neutralising activity and antibody titre in 10 patients with breakthrough infections of the SARS-CoV-2 Omicron variant in Japan일본 SARS-CoV-2 오미크론 변이형 돌발성 감염 환자 10명의 중화 활성 및 항체 역가Article Published on 2022-09-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amino acid Antibody titre Breakthrough infection breakthrough infections caused coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) dose elicited evade examined Immunity induce Japan Mutation Neutralising activity omicron Omicron variant Patient respiratory severe acute respiratory syndrome Coronavirus significantly lower Spike proteins the SARS-CoV-2 titre vaccination variant Wuhan strain [DOI] 10.1016/j.jiac.2022.04.018 PMC 바로가기 [Article Type] Article
Pre-endoscopy coronavirus disease 2019 screening and severe acute respiratory syndrome coronavirus-2 nucleic acid amplification testing in the Veterans Affairs healthcare system: clinical practice patterns, outcomes, and relationship to procedure volume2019년 내시경 전 코로나바이러스 질병 검진 및 중증급성호흡기증후군 코로나바이러스-2 핵산 증폭 검사(재향군인회 의료 시스템): 임상 진료 패턴, 결과 및 시술량과의 관계Article Published on 2022-09-012022-09-11 Journal: Gastrointestinal endoscopy [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Affair analyzed association Breakthrough infection breakthrough infections Characteristics Clinical practice coronavirus disease Coronavirus disease 2019 Coronavirus-2 correlation COVID-19 COVID-19 symptom determine healthcare Healthcare system Impact implication individual NAAT National Negative predictive value nucleic acid nucleic acid amplification nucleic acid amplification testing Omicron variant outcome outcomes pandemic positive Positive predictive value Predictive value reported SARS-CoV-2 SARS-CoV-2 delta screened Screening sensitivity Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 Spearman rank correlation specificity tested the SARS-CoV-2 vaccinated individual vaccinated individuals veteran Volume [DOI] 10.1016/j.gie.2022.04.018 PMC 바로가기 [Article Type] Article
Evaluating risk factors associated with COVID-19 infections among vaccinated people early in the U.S. vaccination campaign: an observational study of five states, January-March 2021Observational Study Published on 2022-09-012022-10-04 Journal: BMC Infectious Diseases [Category] SARS, 변종, 임상, [키워드] 95% CI age breakthrough infections caused CDC circulating COVID-19 COVID-19 vaccine COVID-19 vaccines effective Effectiveness evaluated Evaluating FIVE genomic higher risk immunization incidence individual infected with SARS-CoV-2 Infection Moderna National Observational data Pfizer-BioNTech Poisson regression models Prevent preventing infection proportion recipient recipients reported risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant Sex Surveillance vaccination Vaccine vaccine breakthrough infection Vaccine breakthrough infections. variants of concern virus with COVID-19 [DOI] 10.1186/s12879-022-07702-x PMC 바로가기 [Article Type] Observational Study
Clinical manifestations of COVID-19 breakthrough infections: A systematic review and meta-analysisCOVID-19 돌발 감염의 임상 양상: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-09-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval Analysis asymptomatic infection Breakthrough infection breakthrough infections clinical manifestation clinical manifestations Clinical outcome Coronavirus 2019 COVID-19 COVID-19 infection COVID-19 infections Delta delta variant Effect Effectiveness examined groups heterogeneity Hospitalization individual individuals Infection Invasive mechanical ventilation Meta-analysis Mortality need for oxygen other variants oxygen oxygen supplementation Patient Relative risk risk Risk factors risk of infection significantly significantly higher statistically statistically significant difference Still study heterogeneity supplemental oxygen systematic review Treatment strategies Vaccine vaccine effectiveness variant variants Web of Science [DOI] 10.1002/jmv.27871 PMC 바로가기 [Article Type] Meta-Analysis
Neutralization Titers in Vaccinated Patients with SARS-CoV-2 Delta Breakthrough InfectionsArticle Published on 2022-08-302022-11-15 Journal: mBio [Category] SARS, 변종, 진단, [키워드] analyzed antibody Antibody neutralization Breakthrough infection breakthrough infections caused COVID-19 Delta delta variant determine exhibited humans immune evasion implication laboratory result less neutralization neutralization titer Neutralizing neutralizing antibody Neutralizing antibody titer Patient positive Prevent public health required SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant sera tested threshold titer to define Transmission USA-WA1/2020 vaccinated individual Vaccine vaccine booster variants of concern [DOI] 10.1128/mbio.01996-22 PMC 바로가기
Clinical and Genomic Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) Infections in mRNA Vaccinated Health Care Personnel in New York CityArticle Published on 2022-08-242022-11-16 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome B.1.617.2 Breakthrough infection breakthrough infections Cancer center characterization circulation clade clinical Clustering Cohort coronavirus coronavirus 2 death Delta dominant domination dose Effectiveness epidemiologic feature examined finding genomic hcp healthcare personnel Hospitalization Infection infections isolate laboratory-confirmed Messenger RNA moderate mRNA New York City occurred Post-vaccine respiratory Retrospective study SARS CoV-2 SARS-CoV-2 selection of variant Spread Strong study period Vaccine vaccine effectiveness variant WGS Whole genome sequencing [DOI] 10.1093/cid/ciab886 PMC 바로가기
Coronavirus Disease 2019 Vaccine-Breakthrough Infections Requiring Hospitalization in Mayo Clinic Florida Through August 20212021년 8월까지 플로리다 메이요 클리닉에서 입원이 필요한 코로나바이러스 질병 2019 백신 혁신적 감염Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, [키워드] Breakthrough infection breakthrough infections characterized Comorbidities coronavirus disease Coronavirus disease 2019 COVID-19 delta variant Hospitalization hospitalizations Mayo Clinic Older Patient preventive measure preventive measures single center vaccination Vaccine vaccine-breakthrough. variant [DOI] 10.1093/cid/ciab932 PMC 바로가기 [Article Type] Article
Contact-Tracing Outcomes Among Household Contacts of Fully Vaccinated Coronavirus Disease 2019 (COVID-19) Patients: San Francisco, California, 29 January-2 July 20212019년 코로나바이러스 완전 예방접종(COVID-19) 환자의 가족 접촉자 중 접촉자 추적 결과: 캘리포니아주 샌프란시스코, 2021년 1월 29일-7월 2일Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, [키워드] attack rate breakthrough Breakthrough infection breakthrough infections Contact Contact tracing coronavirus disease Coronavirus disease 2019 COVID-19 Department diagnosed face masking genomic sequencing household household contact household contacts household transmission Households identify index case Neutralizing antibodies occur outcome Patient patients with COVID-19 Positive test positive test result Public public health receive resistance to neutralizing antibodies San Francisco secondary attack rate sequenced symptomatic test result tested Transmission vaccination variant were infected [DOI] 10.1093/cid/ciab1042 PMC 바로가기 [Article Type] Article