Effectiveness of COVID-19 mRNA Vaccines Against COVID-19-Associated Hospitalizations Among Immunocompromised Adults During SARS-CoV-2 Omicron Predominance – VISION Network, 10 States, December 2021-August 2022Article Published on 2022-10-212022-11-15 Journal: Morbidity and Mortality Weekly Report [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] Against Analysis antibody antivirals B.1.1.529 benefit booster booster dose cause circulating Committee component conditions COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines dose doses Effectiveness eligible Hospitalization Hospitalized immunocompromising condition Mask moderate molecular test mRNA network nonpharmaceutical intervention offered omicron Person positive Practice predominant Prophylactic protection Protective receive recipient recommendation recommendations reduced Restricting SARS-CoV-2 therapy vaccination Vaccine variant virus [DOI] 10.15585/mmwr.mm7142a4 PMC 바로가기
Pre-existing humoral immunity to low pathogenic human coronaviruses exhibits limited cross-reactive antibodies response against SARS-CoV-2 in childrenArticle Published on 2022-10-192022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome analyzed anti-S IgG antibody Antigen antigen specific antibody Asymptomatic cause children collected coronavirus cross-react cross-reactive cross-reactive antibody exhibit HCoV-OC43 Hospitalization Humoral immunity IgG antibody Infection low pathogenic human coronaviruses median age mild symptoms Mutant SARS-CoV-2 Neutralizing activity neutralizing antibody nucleocapsid occurred outbreak pathogenic pathogenic human coronavirus question Re-infection reached Receptor binding domain SARS-CoV-2 seropositive sample serum sample Seven SRAS-CoV-2 These data wild-type [DOI] 10.3389/fimmu.2022.1042406 PMC 바로가기
Metagenomic analysis reveals differences in the co-occurrence and abundance of viral species in SARS-CoV-2 patients with different severity of diseaseArticle Published on 2022-10-192022-11-15 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] age Analysis cause characterized clinical manifestation co-occurrence condition COVID-19 COVID-19 patient Deceased disease disease severity DNA virus eukaryotic fraction Hospitalized hospitalized patient Human Identified individuals Measle metagenomic sequencing outcome outcomes Patient presence of comorbidities Prevalence prevalent prevalent virus Prognosis respiratory respiratory virus respiratory viruses Result reveal rotavirus Sample SARS-CoV-2 SARS-CoV-2 infected patient SARS-COV-2 infection SARS-CoV-2 patient Severity of disease significantly more torque Virological virus viruses [DOI] 10.1186/s12879-022-07783-8 PMC 바로가기
Tools to Alleviate the Drug Resistance in Mycobacterium tuberculosisArticle Published on 2022-10-172022-11-15 Journal: Molecules [Category] 진단, [키워드] acid-fast bacillus Antibiotics Asymptomatic cause caused COVID-19 pandemic death detect diagnosed Diagnosis drug Drug discovery drug resistance drug-resistant estimates exhibiting Factor Frequency highlight Host intrinsically isolate isolates majority MDR molecular mechanism mutations Mycobacterium Mycobacterium tuberculosis Nucleic acid detection pathogen reduced reduction in resistance Treatment treatment regimen Tuberculosis WHO [DOI] 10.3390/molecules27206985 PMC 바로가기
Why Does the Omicron Variant Largely Spare Olfactory Function? Implications for the Pathogenesis of Anosmia in Coronavirus Disease 2019Article Published on 2022-10-172022-11-16 Journal: The Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 acute respiratory syndrome alkaline Anosmia cause Cell coronavirus COVID-19 D614G D614G mutation Efficiency Express expressing host cell hydrophobic less Loss of Smell Mucus Mutation olfactory dysfunction Olfactory epithelium olfactory function omicron Omicron variant penetration potential mechanism Prevalence Receptor binding reduce reduced SARS-CoV-2 Support target cell tissue tropism TMPRSS2 transmembrane serine protease variants [DOI] 10.1093/infdis/jiac113 PMC 바로가기
Glycyrrhizin through liquorice intake modulates ACE2 and HMGB1 levels-A pilot study in healthy individuals with implications for COVID-19 and ARDSArticle Published on 2022-10-172022-11-15 Journal: PLoS ONE [Category] 치료제, [키워드] ACE2 ACE2 expression acute respiratory distress alarmin Analysis angiotensin-converting enzyme 2 Antiviral ARDS ARDS patient baseline baseline levels blood sample cause cellular change collected coronavirus disease COVID-19 enrolled enzyme-linked immunosorbent exhibit expression glycyrrhizin healthy individual healthy volunteer HMGB1 hospitalised COVID-19 patient hospitalised patient immunomodulatory property implication in healthy individual in healthy individuals individual individuals liquorice material Mild modulate Non-COVID-19 not different Patient patients pilot study Plasma HMGB1 Potential treatment pro-inflammatory receptor ACE2 reduced reduction in Respiratory disease significantly significantly higher syndrome viral entry were measured with mild disease [DOI] 10.1371/journal.pone.0275181 PMC 바로가기
Small-Molecule RAF265 as an Antiviral Therapy Acts against PEDV InfectionArticle Published on 2022-10-152022-11-15 Journal: Viruses [Category] COVID19(2023년), SARS, 치료제, [키워드] Act acute diarrhea anticancer Antiviral antiviral strategy cause caused cellular cellular translation Concentration coronavirus cytoskeleton. drug effective epidemic diarrhea family Coronaviridae high mortality host cell inhibited inhibitor inhibitory activity magnitude Newborn PEDV pseudotyped RAF265 reduced reduced viral load Replication shown starting point translation treat Vero cells viral entry viral infection Viral vector virus vomiting [DOI] 10.3390/v14102261 PMC 바로가기
Inflammation Causes Exacerbation of COVID-19: How about Skin Inflammation?Article Published on 2022-10-142022-11-16 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] accumulated aging atopic atopic dermatitis bat bat coronaviruses cause Cell China conditions coronavirus COVID-19 Diabetes Mellitus disease Diseases enzyme epidemiological data Europe Exacerbation help highest homology Host Human humans hypertension infect Inflammation Inflammatory inflammatory condition mechanism membrane fusion Middle East occurred poor prognosis promote psoriasis pulmonary disease receptor ACE2 SARS-CoV-2 skin TMPRSS viral infection virus [DOI] 10.3390/ijms232012260 PMC 바로가기
The pre-exposure SARS-CoV-2-specific T cell repertoire determines the quality of the immune response to vaccinationArticle Published on 2022-10-112022-11-15 Journal: Immunity [Category] COVID19(2023년), SARS, 진단, [키워드] age Analysis antigen-reactive T cell enrichment antigen-specific CD4+ T cells arising cause CD154 CD4 CD4+ CD40L contribute correlated COVID-19 defined determine exclusion generate heterogeneity highlight host-response immune response Immunoglobulin induce Infection intrinsic memory T cells pathogen responses SARS-CoV-2 subsequent T cell T cell receptor T cell response T cells TCR TCR tracking vaccination Variability [DOI] 10.1016/j.immuni.2022.08.003 PMC 바로가기
Theoretical investigation on the interactions of microplastics with a SARS-CoV-2 RNA fragment and their potential impacts on viral transport and exposureSARS-CoV-2 RNA 단편과 미세 플라스틱의 상호 작용 및 바이러스 수송 및 노출에 대한 잠재적 영향에 대한 이론적 조사Article Published on 2022-10-102022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect affinity Behavior Behavior and fate cause condition coronavirus coronavirus disease Coronavirus disease-19 COVID-19 determine electrostatic environmental conditions Environmental pollution Evidence exposure to facilitate FIVE greater HBV hepatitis B Hepatitis B virus Human hydrophobic Impact independent independent of inherent Interaction involved Lungs mechanism media Microplastic pollution microplastics molecular molecular dynamic simulations molecular interaction molecular volume Nucleic acid material pandemic pandemic spread parameter polar risk RNA RNA fragment SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 transmission severe acute respiratory syndrome Coronavirus Spread strong interaction surface area temperature the SARS-CoV-2 Transport vacuum virus water [DOI] 10.1016/j.scitotenv.2022.156812 PMC 바로가기 [Article Type] Article