COVID-19 Vaccines in Older Adults: Challenges in Vaccine Development and Policy MakingReview article Published on 2022-08-012022-10-05 Journal: Clinics in Geriatric Medicine [Category] 변종, [키워드] challenge COVID-19 development disability frailty immunosenescence Making Policy Vaccine [DOI] 10.1016/j.cger.2022.03.006 [Article Type] Review article
Syndemic Nature of COVID-19 in Latin American and Caribbean Countries: The Challenge AheadEditorial Published on 2022-07-012022-10-05 Journal: Archives of medical research [Category] 유전자 메커니즘, [키워드] challenge COVID-19 Latin Nature syndemic [DOI] 10.1016/j.arcmed.2022.06.003 [Article Type] Editorial
High Challenge Exercise and Learning Safe Landing Strategies among Community-Dwelling Older Adults: A Randomized Controlled TrialRandomized Controlled Trial Published on 2022-06-162022-10-04 Journal: International Journal of Environmental Research an [Category] 임상, [키워드] age baseline both groups challenge change control group Controlled COVID-19 pandemic decrease Effect effective evaluated exercise Follow-up functions Health status improvement in both group initiated Injury Intervention judo landing learning martial arts men motor skill offered Older Older adults participant physical physical activity physical activity level populations postintervention Psychological Randomized controlled trial Randomly RCT Research significantly Strategy sustained two groups women [DOI] 10.3390/ijerph19127370 PMC 바로가기 [Article Type] Randomized Controlled Trial
Progress and Challenges in Targeting the SARS-CoV-2 Papain-like ProteaseSARS-CoV-2 파파인 유사 프로테아제 표적화의 진행 상황 및 과제Review Published on 2022-06-092022-09-11 Journal: Journal of medicinal chemistry [Category] Coronavirus, COVID19(2023년), SARS, 변종, 치료제, [키워드] addition Antiviral antiviral drug target approval approved causative agent challenge class cleavage clinic combating COVID-19 pandemic Encouraging highlight Host include inhibitor inhibitors innate immune response knowledge mechanism modulate molnupiravir Nirmatrelvir offer pandemic Papain-like protease pharmacokinetic polymerase polyprotein Progress Protease inhibitor Remdesivir Ritonavir SARS-CoV-2 structure-based design targeting the SARS-CoV-2 U.S. FDA Vaccine variant variants viral infection [DOI] 10.1021/acs.jmedchem.2c00303 PMC 바로가기 [Article Type] Review
Challenges of rapamycin repurposing as a potential therapeutic candidate for COVID-19: implications for skeletal muscle metabolic health in older personsCOVID-19의 잠재적인 치료 후보로 라파마이신 용도 변경의 도전: 노인의 골격근 대사 건강에 대한 영향Editorial Published on 2022-06-012022-09-11 Journal: American journal of physiology. Endocrinology and [Category] COVID19(2023년), SARS, 신약개발, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered administration affected aging anabolic anabolic resistance antiviral medication attenuate bed rest block blunting causative agent Cell cell growth challenge clinical trial coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 hospitalization death Decline demonstrated downstream drug Drug repurposing Effect effective effective vaccine Effective vaccines effectors greater growth Health healthy Hospitalization Human implication lack master regulator Mortality MPS mTOR muscle loss muscle mass muscle protein muscle protein synthesis muscle protein synthesis. Older pandemic Pandemics Rapamycin reduced resulting risk SARS-CoV-2 sedentariness Severe infection Skeletal muscle Spread susceptible the disease therapeutic with COVID-19 younger patients [DOI] 10.1152/ajpendo.00064.2022 PMC 바로가기 [Article Type] Editorial
The Successes and Challenges of SARS-CoV-2 Molecular Testing in the United States미국에서 SARS-CoV-2 분자 테스트의 성공과 도전Review Published on 2022-06-012022-09-12 Journal: Clinics in laboratory medicine [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] assays challenge challenges COVID-19 diagnostic Diagnostic method genotyping Laboratory molecular Molecular tests pandemic public health Regulatory Research SARS-CoV-2 Successes. Testing the United State [DOI] 10.1016/j.cll.2022.02.007 PMC 바로가기 [Article Type] Review
Challenges of SARS-CoV-2 Omicron Variant and appropriate countermeasuresSARS-CoV-2 오미크론 변이의 도전과제 및 적절한 대책Review Published on 2022-06-012022-09-11 Journal: Journal of microbiology, immunology, and infection [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Accuracy B.1.1.529 booster cause caused challenge COVID-19 COVID-19 vaccine Critical deaths diagnosed diagnostic Diagnostic accuracy Efficacy help Immune escape Improving increased risk Infection infectious Isolation mild clinical symptom mild clinical symptoms monoclonal antibody Mutation nonpharmaceutical intervention Nonpharmaceutical interventions omicron Omicron variant Omicron variants Panic reduced reduction Reinfection reported Research resulting SARS-CoV-2 Severe case shown South Africa Spread Therapies Treatment treatment failure Vaccine Vaccines variant [DOI] 10.1016/j.jmii.2022.03.007 PMC 바로가기 [Article Type] Review
Low rates of HPV vaccination and cervical cancer screening: Challenges and opportunities in the context of the COVID-19 pandemicDiscussion Published on 2022-06-012022-10-05 Journal: Preventive medicine [Category] 유전자 메커니즘, [키워드] Cancer cervical cancer Cervical precancer challenge COVID-19 COVID-19 pandemic HPV HPV vaccination IMPROVE pandemic Richard SARS-CoV-2 Screening vaccination [DOI] 10.1016/j.ypmed.2022.107070 [Article Type] Discussion
Development of an integrated environmental monitoring protocol for SARS-CoV-2 contamination. Applications at the IRCSS San Martino Polyclinic Hospital in Genoa, ItalySARS-CoV-2 오염에 대한 통합 환경 모니터링 프로토콜 개발. 이탈리아 제노바에 있는 IRCSS San Martino Polyclinic Hospital의 애플리케이션Article Published on 2022-06-012022-09-11 Journal: Environmental research [Category] COVID19(2023년), SARS, 치료기술, [키워드] application assessment biological significance carried Cell challenge Challenge test collected Contamination correlation COVID-19 patients development distance Effectiveness environmental monitoring evaluate evaluated functional Height hospital Hospital contamination in vitro infecting Infection Italy less measure non-specific performed Polyclinic positive predicted Prophylaxis protocol qPCR RNA sampling SARS-CoV-2 SARS-COV-2 infection sensitivity single sampling Spread tested to define Viral RNA virion virus virus spread [DOI] 10.1016/j.envres.2022.112790 PMC 바로가기 [Article Type] Article
Invasive fungal infections in critically ill COVID-19 patients in a large tertiary university hospital in IsraelResearch article Published on 2022-06-012022-10-05 Journal: Journal of critical care [Category] 바이오마커, [키워드] aspergillosis Awareness Candidemia carbapenem challenge co-morbidity collected control group COVID-19 COVID-19 patient COVID-19 patients Critically ill determine Diagnosis Fungal infection high mortality IFI imperative incidence Infection intensive care unit invasive Invasive fungal infection Mortality outcome Patient predictor Result risk factor university hospital [DOI] 10.1016/j.jcrc.2022.154004 [Article Type] Research article