Charlson Comorbidity Index – Page 3 – Communicable Diseases Research

A Tale of Two Surges: Differences in Outcomes in the COVID-19 Pandemic in a Community Teaching Hospital in Massachusetts

Internal Medicine

Published on 2022-01-242022-10-31
Journal: Cureus [Category] COVID-19,

Effect of dexamethasone in patients with ARDS and COVID-19 (REMED trial)—study protocol for a prospective, multi-centre, open-label, parallel-group, randomized controlled trial

ARDS 및 COVID-19 환자에서 덱사메타손의 효과(REMED 시험) - 전향적, 다기관, 공개 라벨, 병렬 그룹, 무작위 대조 시험을 위한 연구 프로토콜

Update

Published on 2022-01-152022-09-10
Journal: Trials [Category] SARS, 임상,

[키워드] 1:1 Administered Adult patients adverse event adverse events age ARDS ARMS Barthel Index Charlson Comorbidity Index clinical Comorbidity conducted consequence Corticosteroid Corticosteroids COVID-19 COVID-19 pneumonia CRP level CRP levels Czech Republic deleterious effect Dexamethasone dexamethasone 6 mg different dose dose doses of corticosteroids Effect Efficacy and safety enrolled EudraCT Factor followed by ICUs Independence Inflammatory intensive care unit intensive care units intravenously life marker mechanical ventilation moderate to severe Mortality once daily Open-label outcome oxygen Oxygen therapy parallel-group participant patients with ARDS patients with COVID-19 patients with moderate per day Pneumonia Prevent primary endpoint protocol Quality of life randomisation randomised randomised controlled trial randomization Randomized controlled trial SARS-CoV-2 virus scale secondary endpoint Secondary endpoints severe ARDS Stratification therapeutic potential Treatment Trial Trial registration university hospital ventilator-free day Ventilator-free days WHO
[DOI] 10.1186/s13063-021-05963-6 PMC 바로가기 [Article Type] Update

Association between pharmaceutical modulation of oestrogen in postmenopausal women in Sweden and death due to COVID-19: a cohort study

스웨덴 폐경 후 여성에서 에스트로겐의 제약 조절과 COVID-19로 인한 사망의 연관성 : 코호트 연구

Epidemiology

Published on 2022-01-142022-08-31
Journal: BMJ Open [Category] COVID19(2023년), Fulltext, MERS, SARS, 치료제,

[키워드] 95% CI absolute risk adjusted Adjustment age annual income augmentation board Board of Health Breast cancer Charlson Comorbidity Index Cohort cohort study Comorbidity confounder control group COVID-19 death decrease defined diagnosed diagnosed with COVID-19 Endocrine Endocrine Therapy Epidemiology groups highest hormone replacement therapy individual Intervention level of education modulation objective outcome measure participant pharmaceutical positive postmenopausal Primary outcome Public Public Health Agency randomised receiving registries remained replacement therapy Result retrospective risk risk of death sex steroids & HRT significantly Statistics Swedish tested therapy Trial variables Welfare women
[DOI] 10.1136/bmjopen-2021-053032 PMC 바로가기 [Article Type] Epidemiology

Neck of Femur Fractures in the First Eight Months of the COVID-19 Pandemic: A UK Systematic Review and Meta-Analysis

Infectious Disease

Published on 2021-12-082022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] 30-Day mortality 95% confidence interval acute respiratory syndrome article Care Charlson Comorbidity Index concurrent infection coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 in patient COVID-19 infection Femur FIVE Fracture Future hip hip and proximal femur trauma incidence include increase Infection item majority Meta-analysis Month Mortality mortality rates mortality risk Neck Neck of femur fracture Odds ratio orthopaedic research outcome pandemic Patient performed postoperative predict remained reported Reporting review risk searched systematic review Time to surgery United Kingdom was performed
[DOI] 10.7759/cureus.20262 PMC 바로가기 [Article Type] Infectious Disease

Compassionate Use of Hydroxychloroquine in Clinical Practice for Patients With Mild to Severe COVID-19 in a French University Hospital

프랑스 대학 병원의 경증 내지 중증 COVID-19 환자를 위한 임상 실습에서 하이드록시클로로퀸의 자비로운 사용

Observational Study

Published on 2021-12-062022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 신약개발, 임상,

[키워드] addition Admission age Analysis analyzed Arterial hypertension Charlson Comorbidity Index clinical Comorbidity conducted confidence interval confounder confounders contraindication contraindications Controlled trial coronavirus disease Coronavirus disease 2019 COVID-19 death decision defined determine dosage effective French group hazard ratio help Hospitalized Hydroxychloroquine hypertension initial intensive care intensive care unit laboratory-confirmed Laboratory-confirmed COVID-19 medical history Mild National Early Warning Score NEWS2 Nonrandomized studies nonrandomized study not significantly different obesity outcome overall survival Patient patients treated Pneumonia Practice primary analysis primary endpoint Propensity score reduced risk reduction retrospective cohort study risk SARS-CoV-2 score severe COVID-19 severity Sex significantly Standard of care suggested symptom onset the mean the median therapeutic therapeutic agent Treatment treatment of COVID-19 university university hospital was performed Weighting with COVID-19
[DOI] 10.1093/cid/ciaa791 PMC 바로가기 [Article Type] Observational Study

COVID-19 and non–COVID-19 pneumonia: a comparison

Research Article

Published on 2021-12-022022-10-28
Journal: Annals of Medicine [Category] COVID-19, SARS,

[키워드] Admission age analyzed average caused Charlson Comorbidity Index Chronic kidney disease chronic obstructive clinical Clinical characteristics clinical feature consequence COVID COVID patient Covid patients COVID-19 COVID-19 disease COVID-19 pandemic disease Duration duration of hospitalization early stage elderly evaluated greater Ground-glass opacities health system healthcare Hospitalization HRCT in-hospital mortality infected patients Laboratory males message Mortality mortality rate Neurological diseases no statistical difference Non-COVID-19 outcome pandemic Pathologies Patient patients performed Pneumonia presence of comorbidity Prevalence pulmonary disease radiological resource resources Result risk factor SARS-CoV-2 SARS-COV-2 infection statistically significant statistically significant difference two group with COVID-19
[DOI] 10.1080/07853890.2021.2010797 PMC 바로가기 [Article Type] Research Article

The Impact of Charlson Comorbidity Index on Mortality From SARS-CoV-2 Virus Infection

Infectious Disease

Published on 2021-11-272022-10-31
Journal: Cureus [Category] COVID-19,

A Multi-Center Retrospective Review of COVID-19 Outcomes in Patients with Lymphoid Malignancy

Conference abstract

Published on 2021-11-232022-10-05
Journal: Blood [Category] 유전자 메커니즘,

[키워드] adaptive addition adjusted age Analysis anti-CD20 Antibody testing anticancer association cancer patient CCI center Characteristics Charlson Comorbidity Index Chemotherapy Clinical characteristics CLL Cohort Comorbidity Complete covariate COVID-19 COVID-19 diagnosis current death Descriptive statistics Diagnosis disease download Effect EMR endpoints equity estimate evaluate event events female figure Final funding Genentech General population Hematologic malignancy high risk higher risk Hoffmann-La Roche Hospital admission humoral immune response Humoral immunity immune defects increased risk indolent Interaction interaction effect Kite lower risk lymphoid lymphoma male malignancies malignancy median monoclonal antibody Mortality Multivariate analysis NHL nucleocapsid Odds ratio outcome outcomes P-value Patient patients positive result Previous studies Prophylaxis Regression model response to vaccination retrospective review risk risk factor SARS-CoV-2 SARS-CoV-2 PCR Seattle Sharp shown speaker statistically significant suggested table therapy USA variable was used were used while with COVID-19
[DOI] 10.1182/blood-2021-146398 [Article Type] Conference abstract

Clinical Characteristics, Complications and Outcomes of Patients with Severe Acute Respiratory Distress Syndrome Related to COVID-19 or Influenza Requiring Extracorporeal Membrane Oxygenation—A Retrospective Cohort Study

Article

Published on 2021-11-212022-10-30
Journal: Journal of Clinical Medicine [Category] COVID-19,

[키워드] 113 patient acute respiratory distress age ARDS bleeding bleeding event Characteristics Charlson Comorbidity Index clinical Clinical characteristics Clinical outcome complex Complication consecutive patient coronavirus disease COVID-19 disease severity ECMO Extracorporeal female Germany ICU Influenza influenza pandemic invasive IQR membrane Mortality multiple organ failure outcome Oxygenation P/F ratio parameter Patient patients with COVID-19 renal replacement therapy respiratory Retrospective analysis SARS-CoV-2 severe ARDS SOFA score syndrome therapy thrombosis treated Treatment two group university utilised VV-ECMO with COVID-19
[DOI] 10.3390/jcm10225440 PMC 바로가기 [Article Type] Article

Clinical characteristics and outcomes of COVID-19 patients admitted to the intensive care unit during the first year of the pandemic in Brazil: a single center retrospective cohort study

Original Article

Published on 2021-11-192022-10-31
Journal: Einstein [Category] COVID-19, SARS,

[키워드] age assessment Betacoronavírus Betacoronavirus Brazil Characteristics Charlson Comorbidity Index clinical Clinical characteristics cohort study Comorbidity conducted Coronavírus coronavirus Coronavirus infections COVID-19 COVID-19 patient critical care outcomes died discharged exhibited extracorporeal membrane oxygenation failure hospital hospital discharge Hospital stay identify in-hospital mortality Infecções por coronavírus intensive care intensive care units interquartile range mechanical ventilation morbidity and mortality Mortalidade Mortality nasal non-survivor Non-survivors Noninvasive ventilation Older organ support outcome outcomes Oxigenação por membrana extracorpórea pacientes com COVID-19 pandemic Patient patients with COVID-19 Physiology predictor prolonged intensive care renal renal replacement therapy resource Respiração artificial Respiration, artificial Resultados de cuidados críticos retrospective cohort study SARS-CoV-2 score severe COVID-19 single center single-center study period Support survivor Survivors Unidades de terapia intensiva Ventilação não invasiva with COVID-19
[DOI] 10.31744/einstein_journal/2021AO6739 PMC 바로가기 [Article Type] Original Article