Knowledge and Awareness of Masks and N95 Respirators Used for COVID-19 Prevention Among Chemical Engineering Students at Al-Balqa Applied University, JordanPublic Health Published on 2022-01-072022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Affect Al-Balqa Applied University analyzed Awareness BAU Chemical chemical engineering students collected Community comparison conducted coronavirus disease COVID-19 COVID-19 pandemic cross-sectional effective effort Engineering filtration IMPROVE investigated Jordan knowledge lack Mask Masks masks and respirators material measure mechanism mechanism of action mechanisms moderate Pandemics prevention Protective provided questionnaire random Respirator Responder Spread SPSS statistically student surgical university World Health Organization [DOI] 10.3389/fpubh.2021.620725 PMC 바로가기 [Article Type] Public Health
A Review of the Current Landscape of SARS-CoV-2 Main Protease Inhibitors: Have We Hit the Bullseye Yet?Review Published on 2021-12-272022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] 3CL-pro inhibitors acute respiratory syndrome analyzed Antiviral cellular ChEMBL Chemical collected Compound Computational chemistry Concentration coronavirus COVID COVID-19 current database DTT effective expressed half-maximal inhibitory concentration in vitro include inhibit inhibitor inhibitory inhibitory activity inhibitory potency landscape M-pro inhibitors protease inhibitors review SARS-CoV-2 the SARS-CoV-2 treat Variation viral replication Virtual screening virus replication [DOI] 10.3390/ijms23010259 PMC 바로가기 [Article Type] Review
Rosin Soap Exhibits Virucidal ActivityResearch Article Published on 2021-12-222022-10-30 Journal: Microbiology Spectrum [Category] COVID-19, SARS, [키워드] activity acute respiratory syndrome Affect antimicrobial Antiviral Chemical Concentration Contamination Control coronavirus coronavirus disease COVID-19 death dependent on derivative Evidence fomite Health help hospitals human disease hygiene IAV in vitro inactivation Infection influenza A virus Influenza virus inhibitory effect mammalian mitigate pandemic pathogenic Prevent produced reduction in Resin respiratory syncytial virus Rosin SARS-CoV-2 shown soap Spread temperature Viral transmission virucidal virus virus inactivation virus infection viruses [DOI] 10.1128/spectrum.01091-21 PMC 바로가기 [Article Type] Research Article
Virtual Screening in Search for a Chemical Probe for Angiotensin-Converting Enzyme 2 (ACE2)안지오텐신-수색 효소 2 (ACE2)에 대한 화학 프로브 검색의 가상 스크리닝Article Published on 2021-12-142022-08-31 Journal: Molecules [Category] SARS, 신약개발, [키워드] ACE ACE2 ACE2 receptor angiotensin-converting enzyme 2 Chemical compounds CPU time demonstrated Drug discovery Efficacy evaluate in silico inhibitors management molecular docking molecular probe probe protocol REAL database SARS-CoV-2 saving Screening Virtual screening [DOI] 10.3390/molecules26247584 PMC 바로가기 [Article Type] Article
Chemical Composition of the Red Sea Green Algae Ulva lactuca : Isolation and In Silico Studies of New Anti-COVID-19 CeramidesArticle Published on 2021-11-292022-10-30 Journal: Metabolites [Category] COVID-19, [키워드] Ulva lactuca activities addition Algae Anticoagulant antioxidant Antiviral antiviral activity biological activity caused ceramide Ceramides Chemical claimed Community compounds Coronavirus disease 2019 COVID-19 derivatives effective electrospray ionization Encephalitis enzyme fatty acids green hACE2 High-resolution human cell human host identify immunomodulatory in silico Approach include inhibiting investigated M pro MPro mass spectroscopy metabolic profiling metabolite New pandemic protease protein complex Red reported Research responsible Safe SARS-CoV-2 the disease the SARS-CoV-2 the SARS-CoV-2 virus Transcription Treatment Ulva viral replication virus [DOI] 10.3390/metabo11120816 PMC 바로가기 [Article Type] Article
Site-Specific Labeling of Endogenous Proteins Using CoLDR ChemistryArticle Published on 2021-11-242022-10-29 Journal: Journal of the American Chemical Society [Category] Coronavirus, SARS, [키워드] addition Affect approach binding binding pocket BTK Cell cells Chemical Chemistry CRBN Degradation demonstrated endogenous fluorescent functional inhibit interactions labeling Ligand maintain Modification MONITOR probe Protein quantification SARS-CoV-2 selective shown stability target protein variety [DOI] 10.1021/jacs.1c06167 PMC 바로가기 [Article Type] Article
Chemical Exposures Affect Innate Immune Response to SARS-CoV-2화학적 노출은 SARS-COV-2에 대한 선천성 면역 반응에 영향을 미칩니다Article Published on 2021-11-192022-08-31 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료제, [키워드] affected Antigen presentation B-cells cells Chemical chemical compounds Compound COVID-19 COVID-19 pathogenesis death rate death rates dendritic Evidence exposure IFN IFN signaling Immune cell immune cells immune system in silico in silico Approach Infection Innate Interaction knowledge molecular molecular basis molecular mechanism molecular mechanisms monocyte Monocytes open outcome overlapping pathological response pathway Pathways populations predict response resulting SARS-CoV-2 SARS-COV-2 infection signaling pathway significant increases in T-cells the SARS-CoV-2 therapeutic interventions Toxicity xenobiotics [DOI] 10.3390/ijms222212474 PMC 바로가기 [Article Type] Article
A chemical-enhanced system for CRISPR-Based nucleic acid detectionCRISPR 기반 핵산 검출을 위한 화학 강화 시스템Article Published on 2021-11-152022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 치료기술, 치료제, [키워드] addition albumin amplification bovine bovine serum albumin buffer Chemical condition COVID-19 COVID-19 pandemic CRISPR detection Detection sensitivity determine determined by develop diagnostics effectors ENhance enhanced help Inclusion isothermal amplification L-proline LAMP lateral flow strip nucleic acid Nucleic acid detection parameter Pathogens point-of-care provide RPA SARS-CoV-2 SARS-CoV-2 pseudovirus secure serum albumin shown viral pathogens [DOI] 10.1016/j.bios.2021.113493 PMC 바로가기 [Article Type] Article
Multi-targeting approach for nsp3, nsp9, nsp12 and nsp15 proteins of SARS-CoV-2 by Diosmin as illustrated by molecular docking and molecular dynamics simulation methodologies분자 도킹 및 분자 역학 시뮬레이션 방법론으로 설명된 Diosmin의 SARS-CoV-2의 nsp3, nsp9, nsp12 및 nsp15 단백질에 대한 다중 표적화 접근Article Published on 2021-11-012022-09-11 Journal: Methods (San Diego, Calif.) [Category] SARS, 치료제, [키워드] absence Analysis analyzed approach approved drug binding binding affinity binding efficiency binding free energy Chemical Clinical stage Clinical stages complexes Compound compounds coronavirus COVID-19 COVID-19 disease demonstrated Diosmin docking score drug Dynamics economic loss effective enzyme experiment FDA FDA-approved drugs food Food and Drug Administration free energy Glide Health highest binding affinity in-silico inhibitor library MD simulation methodology molecular docking molecular dynamics Molecular dynamics simulation multi-targeting non-structural protein non-structural proteins novel Novel coronavirus Nsp12 Nsp15 Nsp3 Nsp9 Protein Protein target protein targets SARS-CoV-2 Schrodinger selected stability target targeting therapeutic Treatment Virtual screening [DOI] 10.1016/j.ymeth.2021.02.017 PMC 바로가기 [Article Type] Article
Viral Inactivation with Emphasis on SARS-CoV-2 Using Physical and Chemical Disinfectants물리적 및 화학적 소독제를 사용한 SARS-CoV-2에 중점을 둔 바이러스 비활성화Review Published on 2021-10-252022-09-12 Journal: The Scientific World Journal [Category] Coronavirus, MERS, SARS, 진단, [키워드] 2-propanol acute respiratory syndrome Analysis Animal coronaviruses canine CCV Chemical Concentration conducted Contact coronavirus coronavirus SARS-CoV-2 Coronaviruses COVID-19 database decontamination disinfectant dose dry heat endemic human coronavirus endemic human coronaviruses Ethanol formaldehyde gastroenteritis glutaraldehyde hands HCoV Health help human coronavirus human coronaviruses humans hydrogen hydrogen peroxide hypochlorite identify inactivated inactivation information Iodine less measure MERS MHV Middle East Middle East respiratory syndrome mouse hepatitis mouse hepatitis virus occur outbreak persistence physical povidone povidone-iodine Prevent prevention propanol researchers Respiratory droplets respiratory tract infection Respiratory tract infections Result SARS-CoV-2 Severe acute respiratory syndrome sodium sodium hypochlorite syndrome TGEV transmissible gastroenteritis virus Transmission ultraviolet light virus virus transmission WHO [DOI] 10.1155/2021/9342748 PMC 바로가기 [Article Type] Review