Rapid Weight Loss, Central Obesity Improvement and Blood Glucose Reduction Are Associated with a Stronger Adaptive Immune Response Following COVID-19 mRNA VaccineArticle Published on 2022-01-052022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] adaptive Adaptive immune response antibodies baseline blood glucose BMI cell-mediated response correlated correlation COVID-19 COVID-19 prognosis diabetes doses Efficacy evaluated Evidence Health humoral IFNγ immune response immunogenicity improvement Infection Loss mRNA mRNA vaccine obesity Patient peptide Prognosis Public Rapid reduced reduction response response to vaccination risk SARS CoV-2 secretion subject vaccination Waist circumference weight weight loss were assessed [DOI] 10.3390/vaccines10010079 PMC 바로가기 [Article Type] Article
COVID-19 in a Patient With Severe Eosinophilic Asthma on Benralizumab Therapy: A Case Report and Review of LiteratureAllergy/Immunology Published on 2021-12-232022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome addition Affect antiviral activity Asthma Asymptomatic COVID-19 benralizumab clinical status contribute coronavirus coronavirus disease Course COVID-19 COVID-19 patients COVID-19 prognosis cytotoxicity deplete Deterioration develop eosinophil Eosinophilic functions IL-5 immunoregulation Infection inflammatory reaction literature literature review modulation monoclonal antibody Patient positive report review SARS-CoV-2 Severe asthma severity of COVID-19 tested the disease therapy [DOI] 10.7759/cureus.20644 PMC 바로가기 [Article Type] Allergy/Immunology
Role of Neutrophil Extracellular Traps in COVID-19 Progression: An Insight for Effective TreatmentReview Published on 2021-12-232022-10-28 Journal: Biomedicines [Category] COVID-19, [키워드] Activation acute respiratory distress acute respiratory distress syndrome alveolar damage ARDS biochemical Biomarker caused clinical Coagulation components confirmed case coronavirus disease correlation COVID-19 COVID-19 patients COVID-19 prognosis Critical Cytokine storm Cytokines cytotoxic activity death demonstrated described develop Disease progression disease severity DNA effective help hematological highest highlighting Histones in some induce Infection Inflammatory inflammatory markers insight Lungs multiple organ failure myeloperoxidase NET NETs neutrophil Neutrophil extracellular trap Neutrophil extracellular traps Neutrophil-to-lymphocyte ratio Neutrophils NLR pandemic pathophysiology Potential biomarker progression Proteases reactive oxygen specy role ROS SARS-CoV-2 severe cases severity signaling pathways syndrome the disease treatment for COVID-19 triggered with COVID-19 [DOI] 10.3390/biomedicines10010031 PMC 바로가기 [Article Type] Review
Impact of visceral fat on the prognosis of coronavirus disease 2019: an observational cohort studyObservational Study Published on 2021-12-102022-10-04 Journal: BMC Infectious Diseases [Category] SARS, 임상, [키워드] 95% CI adipose association assumed AUC BMI body mass index characteristic Chest computed tomography Clarification Computed tomography confounders coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients COVID-19 prognosis Cox regression analysis death defined Disease progression elevated enrolled Evidence fat hazard ratio Health Impact incidence independent risk factor indicated individual investigated kidney mechanical ventilation morbidity morbidity and mortality nasal obesity Observational cohort study oxygen positive predict Predictive Prognosis progressed progression recent remained Respiratory failure Result risk factor severe acute respiratory syndrome coronavirus 2 severe COVID-19 severity significantly stages subjects supplementary material TAT tissue upper pole visceral Visceral adipose tissue with COVID-19 [DOI] 10.1186/s12879-021-06958-z PMC 바로가기 [Article Type] Observational Study
Genomic Characterization of Host Factors Related to SARS-CoV-2 Infection in People with Dementia and Control Populations: The GR@ACE/DEGESCO StudyArticle Published on 2021-12-072022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] APOE added Analysis ApoE association available data characterization chromosomal region confirmed case Control COVID-19 COVID-19 disease COVID-19 prognosis COVID-19 severity Dementia disease disease severity Factor Genetic Genome-wide association study GR@ACE/DEGESCO GWAS Host implicated individual initiative involved locus LZTFL1 Meta-analysis outcome performed SARS-CoV-2 SARS-COV-2 infection sensitivity analysis SLC6A20 statistically significant stratified suggested susceptibility TYK2 with COVID-19 [DOI] 10.3390/jpm11121318 PMC 바로가기 [Article Type] Article
Fighting the pandemic with collaboration at heart: Report from cardiologists in a COVID-19-dedicated Portuguese intensive care unit협력을 중심으로 전염병 퇴치: COVID-19 전담 포르투갈 집중 치료실의 심장 전문의의 보고서Article Published on 2021-12-012022-09-11 Journal: Revista portuguesa de cardiologia [Category] SARS, 치료기술, [키워드] Adult patients age analyzed cardiac marker Cardiac markers Cardiologia Cardiology cardiovascular risk Care changed coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 prognosis Cuidados intensivos Cuidados multidisciplinares de novo Decision making died discharged dysfunction dyslipidemia English Extra-corporeal membrane oxygenation Fighting followed by hypertension ICU intensive care male Manifestations mechanical ventilation membrane mobilization Multidisciplinary care myocardial injury N-terminal N-terminal pro-B-type natriuretic peptide Nova NT-proBNP one patient Oxigenação por membrana extracorporal pandemic Patient Patient care patients with COVID-19 pelo peptide pro-B-type natriuretic peptide report required Respiratory illness severe COVID-19 Spread Takotsubo the disease Vasopressor vasopressor support [DOI] 10.1016/j.repce.2021.11.009 PMC 바로가기 [Article Type] Article
Lung Ultrasound, Clinical and Analytic Scoring Systems as Prognostic Tools in SARS-CoV-2 Pneumonia: A Validating CohortArticle Published on 2021-11-262022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Admission analysed characteristic clinical conducted correlated correlation COVID-19 COVID-19 patient COVID-19 prognosis death determine diagnostic died Early warning score Infection Infectious disease intensive care intubation logistic regression models lung mechanical ventilation Microbiology NEWS2 Non-invasive outcome Patient predict prospective cohort study SARS-CoV-2 score Scoring scoring system single-center Society Spanish statistically statistically significant System the disease Ultrasound [DOI] 10.3390/diagnostics11122211 PMC 바로가기 [Article Type] Article
The Predictive Value of Myoglobin for COVID-19-Related Adverse Outcomes: A Systematic Review and Meta-AnalysisCardiovascular Medicine Published on 2021-11-182022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] 95% CIs 95% confidence interval Adverse adverse outcomes Anomaly article Biomarker cardiac injury cardiac troponin Cardiac troponin I coronavirus disease correlation COVID-19 COVID-19 prognosis database demonstrated elevated Elevation enrolled estimate examined General population higher odd marker meta-analyses Meta-analysis Mortality Myoglobin Odds ratio outcomes Patient patients with COVID-19 Predictive value Prevalence PROSPERO Registration review risk searched severe COVID-19 severe disease severe illness significantly higher value Web of Science with COVID-19 [DOI] 10.3389/fcvm.2021.757799 PMC 바로가기 [Article Type] Cardiovascular Medicine
SARS-CoV-2 infection as a trigger of humoral response against apolipoprotein A-1SARS-CoV-2 감염은 Apolipoprotein A-1에 대한 체액 반응을 유발합니다.Article Published on 2021-11-012022-09-12 Journal: European Journal of Clinical Investigation [Category] MERS, SARS, 진단, [키워드] anti-apolipoprotein A-1 autoantibodies anti-SARS-CoV-2 anti-SARS-CoV-2 IgG association Autoimmune Autoimmunity bioinformatics Case-control clinical settings Cohort COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 prognosis cross-reactivity cytokine epitope Epitopes experiment experimental evidence General population healthy donor high-density homology humoral ICU Patients IgG IgG level immunoassay individual induce intensive care linear Lipoproteins molecular molecular mimicry peptide Prognosis prognostic Protein receptor SARS-CoV-2 SARS-COV-2 infection scrutiny sequence sequence homology seroconversion rate seronegative seropositive individual Significant spike Spike protein target the disease therapeutic TLR2 Toll-like receptor toll-like receptor 2. triggered were assessed were used [DOI] 10.1111/eci.13661 PMC 바로가기 [Article Type] Article
Novel Systemic Inflammation Markers to Predict COVID-19 PrognosisCOVID-19 예후를 예측하는 새로운 전신 염증 표지자Review Published on 2021-10-222022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, [키워드] Admission albumin Biomarkers C-reactive protein C-reactive protein (CRP CAR coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 prognosis CRP death demonstrated Effect Effectiveness Evidence evidence of global pandemic greater group Hospitalization ICU Inflammation inflammatory markers Inflammatory response intensive care intensive care unit intubation lymphocyte marker neutrophil NLR not limited novel novel vaccines Numerous outcome outcomes Patient predict Prognosis prognostic robust SARS-CoV-2 SARS-CoV-2 virus Scientific community severe disease SII systemic systemic immune-inflammation index systemic inflammatory marker systemic inflammatory markers the disease the SARS-CoV-2 virus Vaccine [DOI] 10.3389/fimmu.2021.741061 PMC 바로가기 [Article Type] Review