Coordinate genomic association of transcription factors controlled by an imported quorum sensing peptide in Cryptococcus neoformansCryptococcus neoformans에서 가져온 쿼럼 센싱 펩타이드에 의해 제어되는 전사 인자의 게놈 연관성을 조정합니다.Research Article Published on 2020-09-212022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] acting Affect association binding Cell Cell density cell surface receptor cell wall change chromatin immunoprecipitation Control control cell Coordinate Cryptococcus Cryptococcus neoforman Cryptococcus neoformans Deletion eukaryotic expression form function functions fungal fungal pathogens Gene Expression Genes Genetic genomic genomic studies genomic study human body Hypothesis identify Impact infect Macrophage macrophages mating mechanism Meningitis microbe modulate modulating pathogen pathogenic Pathogens peptide predicted promote promoters proximal quorum regulated required reveal secreted surface receptor target transcription factor transcription factors virulence whole-genome [DOI] 10.1371/journal.pgen.1008744 PMC 바로가기 [Article Type] Research Article
A case report of cryptococcal meningitis associated with ruxolitinibarticle Published on 2020-03-272024-09-02 Journal: Molecular biology of the cell [Category] 대상포진, [키워드] Cryptococcus Immunosuppression Janus kinase inhibitor Meningitis ruxolitinib [DOI] 10.1097/MD.0000000000019587 PMC 바로가기 [Article Type] article
Triple infection with Cryptococcus , varicella-zoster virus, and Mycobacterium abscessus in a patient with anti-interferon-gamma autoantibodies: a case reportCase Report Published on 2020-03-192023-05-23 Journal: BMC Infectious Diseases [Category] Fulltext, 두창, 수두, 홍역, [키워드] Mycobacterium abscessus Anti-interferon-gamma autoantibody Cryptococcus nontuberculous mycobacteria Varicella-Zoster Virus [DOI] 10.1186/s12879-020-4949-4 PMC 바로가기 [Article Type] Case Report
Pulmonary Macrophage and Dendritic Cell Responses to Cryptococcus neoformansArticle Published on 2020-02-112023-08-30 Journal: Frontiers in Cellular and Infection Microbiology [Category] E형 간염, [키워드] Cryptococcus Dendritic cell subsets innate phagocytes macrophage subsets phagocyte-Cryptococcus interaction primary phagocytes pulmonary dendritic cell pulmonary macrophages [DOI] 10.3389/fcimb.2020.00037 PMC 바로가기
Unisexual reproduction promotes competition for mating partners in the global human fungal pathogen Cryptococcus deneoformans단성 생식은 세계적인 인간 곰팡이 병원균인 Cryptococcus deneoformans에서 짝짓기 파트너를 위한 경쟁을 촉진합니다Research Article Published on 2019-09-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence Activation assays benefit bisexual reproduction Cell Cell fusion cell-cell fusion cells colonies colony competing competition complex Contact contribute Courtship Cryptococcus Cryptococcus neoforman Cryptococcus neoformans Diversity ecological Efficiency ENhance enhanced facilitate followed by foraging fungal fungal pathogens Genome growth hyphae hyphal isolate isolates lack life cycle majority MAT a MAT α mating mating type mating types mechanism meiotic recombination Morphological nuclear nuclear fusion nuclei opposite outcrossing pathogen Pathogens pathway pheromone positively correlated prevalent promote promoted Quantitative reflect repressor gene scarcity sexual cycles sexual reproduction strain Strains surface area undergo yeast [DOI] 10.1371/journal.pgen.1008394 PMC 바로가기 [Article Type] Research Article
Convergent evolution of linked mating-type loci in basidiomycete fungi담자균류에서 연결된 교배형 유전자좌의 수렴진화Research Article Published on 2019-09-062022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] allele alleles Analysis analyzed Author bipolar bipolarity Cell chromosomal Combination completion conserved convergent evolution Cryptococcus eukaryotes Evolution fungal fungi fused fusion genomic groups Hypothesis Interaction Lineage loci locus mating mating type mechanism meiosis nuclear nuclear fusion occurred organization pathogenic pheromone physical physically receptor Recombination regions sexual development species subsequent thought transcription factor transcription factor gene Tremellale Tremellales undergo while [DOI] 10.1371/journal.pgen.1008365 PMC 바로가기 [Article Type] Research Article
A case report of disseminated histoplasmosis and concurrent cryptococcal meningitis in a patient treated with ruxolitinibCase Report Published on 2019-03-272024-09-02 Journal: BMC Infectious Diseases [Category] 대상포진, [키워드] Cryptococcus Histoplasmosis Immunosuppression JAKinhibitor ruxolitinib [DOI] 10.1186/s12879-019-3922-6 PMC 바로가기 [Article Type] Case Report
Community-Acquired Meningitis in HIV-Infected Patients in the United Statesarticle Published on 2018-02-282024-09-01 Journal: AIDS patient care and STDs [Category] 폐렴구균 감염증, [키워드] AIDS Cryptococcus HIV Meningitis outcome Streptococcus pneumonia [Article Type] article
PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complexPRM1 및 KAR5는 세포-세포 융합 및 핵종에서 기능하여 Cryptococcus 병원성 종 복합체에서 뚜렷한 양성 및 단성 주기를 유도합니다Research Article Published on 2017-11-272022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence adaptation bisexual reproduction Cell Cell fusion cell-cell fusion cellular processe characterization characterized complex conserved Critical Cryptococcus Cryptococcus neoforman Cryptococcus neoformans de novo demonstrated diploid eukaryotic eukaryotic systems events Evolution forms fungal fungal pathogens fungi fusion protein generate Genetic genotypic hyphae hyphal independent individual involved isolate karyogamy mating type mechanism Morphological nuclear nuclear fusion nuclear membrane observation occur offset opposite organism ortholog orthologs pathogen pathogenic Pathogens pathway phenotypic diversity plants plasma membrane PRM1 produced regulate selfing sexual cycles sexual reproduction Sexuality similarities similarity Stage trajectory undergo yeast [DOI] 10.1371/journal.pgen.1007113 PMC 바로가기 [Article Type] Research Article
Glucosamine stimulates pheromone-independent dimorphic transition in Cryptococcus neoformans by promoting Crz1 nuclear translocation글루코사민은 Crz1 핵 전위를 촉진하여 Cryptococcus neoformans에서 페로몬 독립적인 이형 전이를 자극합니다Research Article Published on 2017-09-122022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Affect Antifungal antifungal therapy attenuate calcineurin caused Cell cellular response clinically complex component Cryptococcal cells cryptococcal meningitis cryptococcosis Cryptococcus Cryptococcus neoforman Cryptococcus neoformans cytoplasm demonstrated disease downstream effector effectors elicited fertile fungal Genetic genetic screen glucosamine glycerol Host Host immune response host immune responses hosts identity immune responses immune-stimulatory independent independent of Interaction isolate limitations majority mammalian MAPK Meningitis morphogenesis Morphological morphological change Morphotype nuclear translocation nucleus Pathogenesis pathway pheromone phosphatase promote promoted PROTECT raise recent reference strain responsible serotype shown signaling pathway stimulate stimulated strain Stress stress response subsequent suppressed switching transcription factor translocation Trigger undergo Vaccine Vaccine development virulence virulent yeast [DOI] 10.1371/journal.pgen.1006982 PMC 바로가기 [Article Type] Research Article