Compassion toward others and self-compassion predict mental and physical well-being: a 5-year longitudinal study of 1090 community-dwelling adults across the lifespanArticle Published on 2021-07-132022-10-04 Journal: Translational Psychiatry [Category] 바이오마커, [키워드] Adults age baseline Compassion cross-sectional Diego evaluate Follow-up Health IMPROVE improvement increase increases in Interaction Intervention inverse correlation Linear regression model loneliness men Mental mixed-effects model outcome outcomes peaking physical predict predicted Predictive markers predictor Prognostic markers rating scale self-compassion target trajectory were used while women [DOI] 10.1038/s41398-021-01491-8 PMC 바로가기 [Article Type] Article
ABO phenotype and clinical correlates of COVID-19 severity in hospitalized patientsResearch Article Published on 2021-06-122022-10-31 Journal: Future Science OA [Category] COVID-19, [키워드] ABO ABO blood type Abstract Admission Analysis Anemia association Blood Blood Group blood phenotype clinical disease confounding variables COVID-19 COVID-19 disease COVID-19 severity death diagnosed with COVID-19 Diagnosis Diego Disease progression Evidence Exploratory analyses Exploratory analysis FIVE help Hispanic hospital Hospitalization Hospitalized hospitalized patient imperative increased risk intensive care intubation male Male sex Manifestations material morbidity and mortality outcome Patient phenotype predictor San Diego severity Support suppress susceptibility total patients with COVID-19 [DOI] 10.2144/fsoa-2021-0045 PMC 바로가기 [Article Type] Research Article
AI-guided discovery of the invariant host response to viral pandemics바이러스 전염병에 대한 불변 숙주 반응의 AI 유도 발견Research Paper Published on 2021-06-112022-09-11 Journal: EBioMedicine [Category] MERS, 바이오마커, 진단, 치료제, [키워드] “cytokine storm” abrogate ACE2 acting analyzed Angiotensin converting enzyme (ACE)-2 Antiviral antiviral agent Apoptosis approach Artificial intelligence/machine learning Boolean equivalent clusters candidate drugs cause cell senescence center clinical conserved Cooperative Coronavirus COVID-19 coronavirus disease Coronavirus disease 2019 COVID-19 cytokine Cytokine storm dataset determine Diego disease severity EIDD-2801 elevated ENCODE entry of SARS-CoV-2 epithelial facilitate fatal COVID-19 fatal disease fatality finding Fund funding hamster Healthcare system High-dose host cells Host immune response host response Human IL15 IL15RA immune response immunologist implicated in viral Interleukin 15 (IL15) knowledge limit limits LJI lung Lung alveoli lung epithelial Lungs myeloid cell myeloid cells natural killer (NK) cells Neutralizing antibodies neutralizing antibody NIH NK cell office over Pandemics paradoxical Patient plasma Plasma levels President Program Quantitative receptor scientist signature STEM stem cell subset supported System therapeutic to define transcriptomic University of California utility Viral virus was used [DOI] 10.1016/j.ebiom.2021.103390 PMC 바로가기 [Article Type] Research Paper
The Southern California Extracorporeal Membrane Oxygenation Consortium During the Coronavirus Disease 2019 PandemicConcepts in Disaster Medicine Published on 2021-06-082022-10-31 Journal: Disaster Medicine and Public Health Preparedness [Category] COVID-19, [키워드] benefit Clinical practice Community coordinator coronavirus coronavirus disease COVID-19 Diego ECMO effective eligible patient Extracorporeal extracorporeal membrane oxygenation guideline Human lack pandemic Pandemics participant Patient physician resource Resource allocation resources seeking service The United States United States [DOI] 10.1017/dmp.2021.179 PMC 바로가기 [Article Type] Concepts in Disaster Medicine
Safety and efficacy of Ayurvedic interventions and Yoga on long term effects of COVID-19: A structured summary of a study protocol for a randomized controlled trialCOVID-19의 장기적인 영향에 대한 아유르베다 중재 및 요가의 안전성 및 효능: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-06-032022-09-10 Journal: Trials [Category] MERS, SARS, 임상, [키워드] 1:1 Acute coronary syndrome acute respiratory distress acute respiratory distress syndrome Adverse Adverse drug reaction Agastya Agastya Haritaki alcoholism ARDS Arm arrhythmia Ashwagandha Atrial fibrillation Ayurveda baseline biochemical blinded Blinding calculated Care CBC change chronic respiratory disease clinical clinical assessment Clinical Management Protocol comparator completion Computed tomography conducted confidence confidence level coronary syndrome COVID 19 COVID-19 COVID-19 case Critically ill Critically ill patient critically ill patients CTRI D-dimer depressive diabetes Diabetes Mellitus diagnosed Diego disease dropout rate drug drug reaction Effect Efficacy element eligible enrolled enrolment evening excluded exploratory study generate GMP Government Government of India group hematological hepatic disease HIV HRCT hs-CRP hypersensitivity IgM antibodies IgM antibody illness illnesses immunosuppressive medications Impact impaired cognition index India intensive care intensive care unit Intervention invasive respiratory support journal Laboratory parameters lactating women Level life long term long-COVID malignancy management motor neuron motor neuron disease multiple sclerosis Myocardial infarction negative RT-PCR number objective Open-label open-label design outcome parallel group parameter participant Participants past history Patient Pharmaceutical Company Pittsburgh positive RT-PCR Post-COVID pregnant Previous studies protocol provided pulmonary Pulmonary function test pulmonary tuberculosis Quality Quality of life random randomised randomised controlled trial Randomized Randomized controlled trial recruitment Registered registry rehabilitation renal renal disease respiratory Respiratory disease respiratory distress Respiratory function Safety Sample Sample size SARS CoV SARS CoV-2 SARS-CoV-2 scale Science score secondary Secondary outcomes Sex Shortness of breath Sleep sleep quality SPSS Standard deviation status stroke study duration study group study period Study protocol Subjective substance dependence supplementary material syndrome Tablet the study group timeline Trial Trial registration Tuberculosis Version warm water water website WHO yoga [DOI] 10.1186/s13063-021-05326-1 PMC 바로가기 [Article Type] Letter
A novel one-step quick assay for detection of SARS-COV2 antibodies across mammalian speciesBiotechnology Published on 2021-04-272022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] acute respiratory syndrome aggregation antibodies antibody Bank can be used caused Community coronavirus Culture death detect Diego Escherichia coli Fluorescence human infection human serum immunoassay lateral flow immunoassay LFIA mammalian negative controls nucleocapsid protein Patient patients positive Protein rapid antibody test SARS-CoV2 secondary antibody sensitivity serological test serum sample serum samples specificity universal test virus virus infection were used [DOI] 10.7717/peerj.11381 PMC 바로가기 [Article Type] Biotechnology
Whole-genome sequencing of SARS-CoV-2 reveals the detection of G614 variant in PakistanSARS-CoV-2의 전체 게놈 시퀀싱은 파키스탄에서 G614 변이체의 검출을 보여줍니다Research Article Published on 2021-03-232022-08-13 Journal: PLoS ONE [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amino acid Analysis aspartic acid characteristic China clade coronavirus D614G D614G mutation Diego Evolution FIVE G614 variant genetic diversity Genome Genome sequences genomic GISAID glycine highlight Illumina Inc. India lead library Missense Mutation mutations NCBI Oman oropharyngeal swab oropharyngeal swabs pandemic Patient Phylogenetic analysis positive PrEP prevalent real-time RT-PCR Region respiratory reveal RNA SARS-CoV-2 SARS-CoV-2 strain selected sequence sequences Sequencing severe acute respiratory syndrome Coronavirus shown Slovakia Spike protein Spread strain Strains submitted United States virus Virus evolution viruses was performed whole genome Whole genome sequencing whole-genome whole-genome sequencing [DOI] 10.1371/journal.pone.0248371 PMC 바로가기 [Article Type] Research Article
High-Throughput Wastewater SARS-CoV-2 Detection Enables Forecasting of Community Infection Dynamics in San Diego CountyObservation Published on 2021-03-022022-10-29 Journal: mSystems [Category] COVID-19, [키워드] Accuracy acute respiratory syndrome alleviate approach ARIMA assessment Asymptomatic automated average Clinical symptoms clinically Community comparison Concentration coronavirus coronavirus disease correlated strongly COVID-19 detect detection Diego Dynamics Efficiency Epidemics Epidemiology estimate estimates faster Forecasting Infection information outbreak predict Prevalence prevalence rate processed protocol reducing reported robust SARS-CoV-2 scaled up sensitivity shown Surveillance Treatment Viral detection viral genome virus Volume wastewater [DOI] 10.1128/mSystems.00045-21 PMC 바로가기 [Article Type] Observation
Real-Time Continuous Glucose Monitoring During the Coronavirus Disease 2019 Pandemic and Its Impact on Time in Range코로나바이러스 질병 2019 팬데믹 동안 실시간 연속 혈당 모니터링 및 범위 내 시간에 미치는 영향Comparative Study Published on 2021-03-012022-09-12 Journal: Diabetes technology & therapeutics [Category] SARS, 진단, [키워드] CDC center change changes in Chicago Continuous Continuous glucose monitoring Control coronavirus disease COVID-19 COVID-19 mortality COVID-19 pandemic diabete diabetes Diego examined FIVE Glucose glycemic glycemic control greater Impact improvement Inc. individual Los Angeles median Metrics MONITOR monitoring New York pandemic parameters prevention proportion Public Range reflected Region regions socioeconomics specificity Standard deviation System The United States time Time-in-range (TIR) user were used [DOI] 10.1089/dia.2020.0649 PMC 바로가기 [Article Type] Comparative Study
Evaluation of two fluorescence immunoassays for the rapid detection of SARS-CoV-2 antigen—new tool to detect infective COVID-19 patientsBiochemistry Published on 2021-01-212022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] antigen detection automated chain characterized clinical sample contagiousness Corporation COVID-19 COVID-19 diagnosis COVID-19 patient detect Diagnosis Diagnostic method Diego early stage evaluated identify immunoassay Inc. indicate individuals Infection infective Laboratory medium Nasopharyngeal swab Patient positive Rapid diagnostic test reaction reduce Result RT-PCR SARS-CoV-2 SARS-CoV-2 antigen SD Biosensor sensitivity significantly specimens symptom onset threshold Transport USA Viral load [DOI] 10.7717/peerj.10801 PMC 바로가기 [Article Type] Biochemistry