Synthetic repurposing of drugs against hypertension: a datamining method based on association rules and a novel discrete algorithmMethodology Article Published on 2020-07-162022-10-27 Journal: BMC Bioinformatics [Category] Coronavirus, Fulltext, SARS, [키워드] Algorithm applied approaches association Combination computational method COVID-19 criteria Data mining datasets detect different disease dosages drug Drug repurposing DrugBank Efficacy help hypertension indicated introduced KEGG medication Optimization algorithm reduce reducing required researcher Result statistical synthetic Synthetic repurposing Therapeutic benefit Toxicity treat Treatment [DOI] 10.1186/s12859-020-03644-w PMC 바로가기 [Article Type] Methodology Article
SARS-CoV-2: An Update on Potential Antivirals in Light of SARS-CoV Antiviral Drug DiscoveriesReview Published on 2020-06-232022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] 2019-nCoV anti-SARS-CoV-2 antibodies Antiviral antivirals CoV COVID-19 CoVs death deaths described different disease drug drugs effective Fatality rate group Human humans illnesses in vitro in vivo infections life-threatening LIGHT MERS-CoV Middle East mild respiratory MOST outbreak Patient Potential Research resource respiratory resulting RNA virus Safe SARS-CoV SARS-CoV-2 SARS-CoV-2 replication sequence identity severe respiratory disease Severe respiratory distress shown Spread spread to syndrome therapeutic strategy treat Viral pneumonia virus Wuhan, China [DOI] 10.3390/vaccines8020335 PMC 바로가기 [Article Type] Review
The Network of Angiotensin Receptors in Breast CancerReview Published on 2020-05-272022-10-31 Journal: Cells [Category] COVID-19, [키워드] ACE1 ACE2 acute respiratory syndrome Analysis angiotensin AT1R AT2R Breast Breast cancer Cancer candesartan component Compound coronavirus COVID-19 disease different disease Disruption drug target drugs Effect Endocrine expressed G-protein hormone human physiology identify immune system knowledge losartan MasR molecular MRGD multifactorial network offer pathology pathway Pathways produced proliferative Protein RAS receptor renin-angiotensin system Signaling transmembrane Treatment [DOI] 10.3390/cells9061336 PMC 바로가기 [Article Type] Review