distinguishing

[키워드] allele alleles amino-acid Analysis Antigen applicability binding site bone-marrow transplant bone-marrow transplants breadth common allele common alleles core alleles Defense determined by develop distinguishing domain Donor donors effort engage exponential growth Facilitating Families family family member Frequency functional Genetic variation glycoprotein growth HLA HLA class I HLA class I alleles HLA class I glycoproteins HLA complex HLA gene HLA genes HLA type HLA variation HLA-A HLA-B HLA-C HLA-C alleles homologous human gene human genes Human genome human population human populations immune functions immune reaction immune system genes incidence individuals Infection kill lymphocyte majority MOST Mutation mutation rate nucleotide nucleotides Older Patient peptide peptides Point mutation polymorphism populations Positive selection predict produced random receptors recombinant recombinants registries required selected sequence sequenced Sequencing Single nucleotide polymorphism single nucleotide polymorphisms Spread subject Substitution the patient variant variants Variation Viral viral infections
[DOI] 10.1371/journal.pgen.1006862 PMC 바로가기 [Article Type] Research Article