Model-based cost-effectiveness analysis of oral antivirals against SARS-CoV-2 in Korea국내 SARS-CoV-2에 대한 경구용 항바이러스제의 모델 기반 비용 효율성 분석Article Published on 2022-01-012022-09-11 Journal: Epidemiology and Health [Category] SARS, 치료제, [키워드] Admission Adult patients Adults Analysis Antiviral antiviral agent Antiviral agents calculated Care coronavirus disease Coronavirus disease 2019 Cost-effectiveness analysis country COVID-19 COVID-19 patient Efficacy Elderly patient elderly patients Emergency use group health system Hospital admission Hospitalization ICU less medical system Mild-to-moderate molnupiravir Nirmatrelvir Patient patients predicted reduce reducing Ritonavir SARS-CoV-2 Severe case severe COVID-19 Severe patient standard care symptomatic Treatment underlying disease underlying diseases [DOI] 10.4178/epih.e2022034 PMC 바로가기 [Article Type] Article
How Does COVID-19 Pandemic Impact on Incidence of Clostridioides difficile Infection and Exacerbation of Its Gastrointestinal Symptoms?Medicine Published on 2021-12-132022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Clostridioides difficile infection addition Affect all age groups alteration Antibiotic therapy Antibiotic treatment Antibiotics antimicrobial Antiviral Bacterial infection cephalosporins Clostridioide Clostridioides difficile infection colonization resistance complicate contributing to Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 infection COVID-19 pandemic COVID-19 patients death develop diarrhea elderly Elderly patient elderly patients Exacerbation excessive use explain facilitated fecal Gastrointestinal gut microbiota healthcare highlight Hospitalized hospitalized patient immunomodulatory drug Impact incidence infection with COVID-19 lung involvement manifestation microbial infection Mortality nasopharyngeal NSAIDS organ outcome pathogen Pathogenesis Pathogens Patient patients with COVID-19 persistence physician presence of comorbidity receiving reduced risk risk factor SARS-CoV-2 SARS-CoV-2 viral particle severe disease Spread Symptom Transmissibility Transmission virus entry widespread with COVID-19 [DOI] 10.3389/fmed.2021.775063 PMC 바로가기 [Article Type] Medicine
Epidemiological features of COVID-19 patients with prolonged incubation period and its implications for controlling the epidemics in ChinaResearch Published on 2021-12-092022-10-28 Journal: BMC Public Health [Category] COVID-19, SARS, [키워드] accelerated adjusted administration analyzed association China clinical feature Clinical practice Clinical severity COVID-19 COVID-19 case COVID-19 patient determinant disease onset elderly patients Epidemics epidemiological Evidence exceeded extreme feature implication Incubation period Level Local lower risk measure Patient Poisson regression model Prolonged incubation period provide quarantine reduced remained reported Result SARS-CoV-2 South supplementary material Transmissibility were used [DOI] 10.1186/s12889-021-12337-9 PMC 바로가기 [Article Type] Research
Serology-based therapeutic strategy in SARS-CoV-2-infected patientsSARS-CoV-2 감염 환자의 혈청학 기반 치료 전략Article Published on 2021-12-012022-09-12 Journal: International immunopharmacology [Category] MERS, SARS, 진단, [키워드] Admission anti-inflammatory treatment antibody B cell benefit convalescent plasma Convalescent plasma therapy COVID-19 Dexamethasone disease early administration elderly patients High-dose Hospitalization immune response immunological Immunosuppressed Immunotherapy impair individual Infection intensive care life-threatening lung damage lymphocyte lymphoid NK cell not affect Patient patients patients with SARS-CoV-2 plasma positive serology presence of antibody progression receive required SARS-CoV-2 SARS-CoV-2-infected patient serology T cell T cells the patient the SARS-CoV-2 virus therapeutic strategy therapy Tocilizumab Treatment virus [DOI] 10.1016/j.intimp.2021.108214 PMC 바로가기 [Article Type] Article
A comparison between virus- versus patients-centred therapeutic attempts to reduce COVID-19 mortalityCOVID-19 사망률을 줄이기 위한 바이러스 중심 치료와 환자 중심 치료 간의 비교Review Published on 2021-12-012022-09-10 Journal: Emerging Microbes & Infections [Category] SARS, 치료제, [키워드] ACE2 acute respiratory disease acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aging angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 anti-inflammatory treatment anti-inflammatory treatments Antiviral antivirals bind caused changed Comorbidities coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 mortality death rate death rates Dexamethasone dysfunction Effectiveness effort elderly elderly patients enzyme explain hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient hospitalized patients Infection inhibit limit majority Mas receptor Mortality Patient patients patients hospitalized reduce Renin renin-angiotensin system replicative required respiratory Respiratory failure SARS-CoV-2 SARS-CoV-2 viral load Scientific community severe acute respiratory syndrome Coronavirus severe COVID-19 symptoms severity severity of symptom Spike protein syndrome the disease the spike protein therapeutic therapeutic option therapeutic options therapeutic strategy those with comorbidity Tocilizumab Treatment Viral Viral load virus with COVID-19 [DOI] 10.1080/22221751.2021.2006579 PMC 바로가기 [Article Type] Review
Investigation of a COVID-19 Outbreak and Its Successful Containment in a Long Term Care Facility in QatarPublic Health Published on 2021-11-262022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] age Artery average blood glucose Care case sery Comorbidities Comorbidity Compliance Contact tracing Containment Coronary COVID-19 COVID-19 complications COVID-19 outbreak COVID-19 positive patient Deceased develop effective elderly elderly patients Evidence facility females Infection infection control Infection prevention Intensive investigation Long long term care lung management material measure outbreak pandemic Patient patients persistent Personal protective equipment prevention preventive measure protocol Qatar radiological recommendation retrospective Seven symptomatic term the patient Treatment were assessed [DOI] 10.3389/fpubh.2021.779410 PMC 바로가기 [Article Type] Public Health
Increasing Burden of Nursing Care on the Treatment of COVID-19 Patients in the Aging Society: Analyses During the First to the Third Wave of Pandemic in Kyoto City, JapanMedicine Published on 2021-11-182022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% confidence interval activity Admission aging aging society Anxiety burden Care center Characteristics Chronic kidney disease city Cluster Complication coronavirus disease COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients daily living Diabetes Mellitus discharge disease disease severity duration of hospitalization Elderly patient elderly patients enrolled evaluate Health healthcare healthcare worker Healthcare workers hospital Hospitalization hospitalized COVID-19 patient hospitals Increasing Intervention Japan Kyoto Mental Mental Disorders Mortality Nursing nursing care Older organization outcome P -value pandemic Patient physical Poor poor prognosis prevalent proportion reduce required resource resources significantly significantly more study period the patient underlying disease unique Wave with COVID-19 [DOI] 10.3389/fmed.2021.767110 PMC 바로가기 [Article Type] Medicine
Analysis of SARS-CoV-2 haplotypes and genomic sequences during 2020 in Victoria, Australia, in the context of putative deficits in innate immune deaminase anti-viral responses2020년 호주 빅토리아에서 SARS-CoV-2 일배체형 및 게놈 서열 분석Article Published on 2021-11-012022-09-11 Journal: Scandinavian journal of immunology [Category] SARS, 변종, [키워드] ADAR analysed Analysis Anti-viral anti-viral response anti-viral responses APOBEC APOBEC and ADAR deamination motifs Care cascades coronavirus vaccine COVID‐19 COVID‐19 haplotypes curated Data analysis Deamination death deficiency Department described Elderly patient elderly patients Epidemics epidemiological epidemiological data explain expression Genetic genomic sequence Government Haplotype help Human Hypothesis immune implication infected patient Infection innate immune Innate immunity interferon majority Mutagenesis occurred Patient predicted proportion response SARS-CoV-2 SARS-CoV-2 epidemic SARS-CoV-2 genome SARS-CoV-2 genomes stimulated Support tested Vaccine development variant Victoria Wave [DOI] 10.1111/sji.13100 PMC 바로가기 [Article Type] Article
The significant impact of Coronavirus disease 2019 (COVID-19) on in-hospital mortality of elderly patients with moderate to severe traumatic brain injury: A retrospective observational studyObservational Study Published on 2021-11-012022-10-05 Journal: Journal of clinical neuroscience : official journa [Category] SARS, 임상, [키워드] analyzed Anticoagulant Brain cause Cohort Coronavirus disease 2019 correlated COVID-19 COVID-19 disease death discharge drug elderly Elderly patient elderly patients evaluated hospital hyperglycemia In-hospital in-hospital mortality increased risk independent risk factor Infection investigated Laboratory Logistic regression analysis moderate mortality rate Other pandemic Patient patient population patients receiving treatment patients with COVID-19 positive predictor radiological retrospective risk scale significantly Traumatic brain injury variable [DOI] 10.1016/j.jocn.2021.09.029 PMC 바로가기 [Article Type] Observational Study
Results of the Second Phase of the GER-e-TEC Experiment concerning the Telemonitoring of Elderly Patients Affected by COVID-19 Disease to Detect the Exacerbation of Geriatric SyndromesArticle Published on 2021-10-292022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] affected age alerts Analysis average Care concerning conducted coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 disease death decompensated heart failure deteriorate Deterioration died disorder elderly Elderly patient elderly patients Exacerbation experiment France Gender general condition geriatric syndromes global public health Health Hospital stay Hospitalization hospitalized patients MyPredi platform not affected pandemic Patient per day phase positive Predictive Result risk second sensitivity syndrome Telemonitoring the epidemic the mean took place university were recorded [DOI] 10.3390/jpm11111117 PMC 바로가기 [Article Type] Article