Utilization of the Abbott SARS-CoV-2 IgG II Quant Assay To Identify High-Titer Anti-SARS-CoV-2 Neutralizing Plasma against Wild-Type and Variant SARS-CoV-2 VirusesArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 95% confidence interval Abbott Abbott SARS-CoV-2 IgG acute respiratory syndrome Analysis approach authorization BAU Beta binding antibody unit Canada CCP characterized Chicago Chicago IL clinical trial convalescent convalescent plasma coronavirus COVID-19 COVID-19 convalescent plasma Cutoff Delta disease course drug Emergency EUA evaluated Evidence experiment FDA food Gamma highest hospitalized patient Humoral immunity identify IgG immune IMPROVE Mann-Whitney U method comparisons Neutralization assay Neutralizing neutralizing antibody outcome Patient patient group plaque reduction neutralization plaque reduction neutralization. plasma PRNT quantitative determination required SARS-CoV-2 SARS-CoV-2 antibody selected significantly specimen tested the SARS-CoV-2 time-consuming treat United State utilization variant VLP VoC wild-type with COVID-19 [DOI] 10.1128/spectrum.02811-22 PMC 바로가기
A review of clinical efficacy data supporting emergency use authorization for COVID-19 therapeutics and lessons for future pandemicsArticle Published on 2022-10-012022-11-15 Journal: Clinical and translational science [Category] COVID19(2023년), SARS, 치료제, [키워드] Anti-inflammatory Antiviral approved authorization chloroquine/hydroxychloroquine Clinical data Clinical efficacy clinical evidence clinical study clinical trial coronavirus disease COVID-19 COVID-19 pandemic COVID-19 therapeutics Critical demonstrated drug Efficacy Emergency Emergency use authorization EUA Evidence FDA food Guidance majority medication Pandemics public health emergency question Randomized controlled trial RCT Regulatory Resilience statistically significant submitted subsequent Support supported therapeutic withdrawn [DOI] 10.1111/cts.13384 PMC 바로가기
Mental health needs associated with COVID-19 on the diamond princess cruise ship: A case series recorded by the disaster psychiatric assistance teamResearch article Published on 2022-10-012022-10-05 Journal: International Journal of Disaster Risk Reduction [Category] 진단, [키워드] addition Anxiety assistance case sery collected Coronavirus disease 2019 counseling COVID-19 diamond Diamond Princess disaster DPAT Emergency event Evidence examined facilitate Health ideation Infection prevention Japan measure men mental health mental health issue mental health issues Mental health needs physical positive Princess Psychiatric Psychological public health quarantine recorded response self-care stress-related symptom Support team variety with COVID-19 women Yokohama [DOI] 10.1016/j.ijdrr.2022.103250 [Article Type] Research article
Early Lung Ultrasound Findings in Patients With COVID-19 Pneumonia: A Retrospective Multicenter Study of 479 PatientsArticle Published on 2022-10-012022-11-15 Journal: Journal of Ultrasound in Medicine [Category] COVID19(2023년), SARS, 진단, [키워드] Accuracy acute respiratory syndrome categorical variable chest X-ray consolidation continuous variable coronavirus coronavirus disease COVID COVID negative patient COVID-19 CXR Department diagnosed Diagnosis diagnostic distress Emergency enrolled evaluate Fever finding interstitial lung Lung ultrasound median molecular molecular test MOST multicenter multicenter study normal Patient patient cohort percentage performed Physicians Pneumonia point of care point-of-care positive presenting radiologic radiologist regions Retrospective study SARS-CoV-2 Sex standard error Ultrasound was performed were expressed White blood cell with COVID-19 [DOI] 10.1002/jum.15944 PMC 바로가기
Monkeypox: A Comprehensive ReviewReview Published on 2022-09-292023-06-09 Journal: Viruses [Category] 원숭이두창, [키워드] Emergency emerging viral infectious diseases Epidemic international concern prevention public health vaccination zoonosis [DOI] 10.3390/v14102155 PMC 바로가기 [Article Type] Review
A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodiesArticle Published on 2022-09-122022-11-15 Journal: Journal of Biomedical Science [Category] SARS, 변종, 신약개발, 치료제, [키워드] abrogated acute respiratory syndrome addition Analysis antibodies antibody Antiviral antiviral drugs authorization BNT162b2 clinical benefits Clinical data clinical trial coronavirus COVID-19 Critical diagnostic distribution drug drugs Effect Effectiveness Efficacy effort Emergency global public health help Infection mRNA vaccines mRNA-1273 mutant strain Mutation Neutralizing antibodies neutralizing antibody neutralizing effect novel coronavirus disease omicron overcome pandemic presenting problems Regulatory SARS-CoV-2 SARS-CoV-2 strains SARS-CoV-2 variant Scientific community shown small molecule Small molecule antiviral drugs small molecule drugs Support the spike protein therapeutic Therapeutics Treatment utility Vaccine Vaccine development Vaccines variant variants widespread [DOI] 10.1186/s12929-022-00852-9 PMC 바로가기
Cheminformatics-Based Discovery of Potential Chemical Probe Inhibitors of Omicron Spike ProteinArticle Published on 2022-09-072022-11-15 Journal: International Journal of Molecular Sciences [Category] SARS, 변종, 진단, 치료제, [키워드] ACE2 Antiviral compound antiviral drug authorization bind carried Chemical Compound compounds COVID-19 COVID-19 pandemic database determine DFT drug treatment effective Emergency evaluate facilitate FDA FIVE Health human Angiotensin-converting enzyme identify IMPROVE in vitro in vivo indicated Initially Invasion less Lineage MD simulation molecular monoclonal antibody mutant neutralizing monoclonal antibody omicron Potential profile Protein protein-ligand interaction provided raised reactivity receptor reduce Reinfection Replication rising risk SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants spike Spread the Spike therapeutic intervention vaccination Vaccine-induced immunity variant Virtual screening virus virus transmission was performed [DOI] 10.3390/ijms231810315 PMC 바로가기
EQUIP emergency: can interventions to reduce racism, discrimination and stigma in EDs improve outcomes?Clinical Trial Published on 2022-09-022022-10-05 Journal: BMC health services research [Category] 임상, [키워드] activities activity age Analysis Canada Care clinical collected Community COVID 19 death Department dimension discrimination Emergency Emergency Departments Epidemic equity group Health Health disparities health equity Health inequity IMPROVE Indigenous intensity Intervention Intervention research longitudinal mounted Multiple regression overdose pandemic Patient post-intervention presenting promote question racism reduce reduction Research resource robust shown sick significant decrease significantly Stigma supported survey tested Throughout the study trauma was tested worsening [DOI] 10.1186/s12913-022-08475-4 PMC 바로가기 [Article Type] Clinical Trial
Successful recruitment of monolingual Spanish speaking Latinos to university phase II and III outpatient COVID-19 clinical treatment trials in Northern CaliforniaClinical Trial Published on 2022-09-012022-10-05 Journal: Contemporary clinical trials [Category] 유전자 메커니즘, 임상, 진단, 치료법, [키워드] authorization Clinical treatment clinical trial contribute COVID-19 Emergency Enrollment EUA FDA Health Latino Mild Moderate COVID-19 monoclonal antibody Outpatient patients Population receive recruited recruitment research coordinator Spanish Stanford University Treatment treatment trial Trial with COVID-19 [DOI] 10.1016/j.cct.2022.106891 [Article Type] Clinical Trial
The Effects of Motivational Messages Sent to Emergency Nurses During the COVID-19 Pandemic on Job Satisfaction, Compassion Fatigue, and Communication Skills: A Randomized Controlled TrialResearch article Published on 2022-09-012022-10-05 Journal: Journal of emergency nursing [Category] 임상, [키워드] Administered affected age assigned communication Communication skills Compassion Compassion fatigue conducted control group control groups Controlled COVID-19 COVID-19 pandemic Effect Emergency Factor fatigue hospital IMPROVE Intervention intervention group Isolation İstanbul job Job satisfaction message motivation no significant difference Nurse Nursing participant physically psychologically Randomized Randomly reducing Research resources Result Satisfaction scale Sent significantly higher significantly lower skill [DOI] 10.1016/j.jen.2022.06.001 [Article Type] Research article