Double-blind placebo-controlled randomized clinical trial to assess the efficacy of montelukast in mild to moderate respiratory symptoms of patients with long COVID: E-SPERANZA COVID Project study protocol장기간 COVID-19 환자의 경증에서 중등도의 호흡기 증상에 대한 몬테루카스트의 효능을 평가하기 위한 이중 맹검 위약 대조 무작위 임상 시험: E-SPERANZA COVID 프로젝트 연구 프로토콜Study Protocol Published on 2022-01-062022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 acute phase Affect Ageusia Analysis Anosmia approved assessment asthenia Awareness Brain Clinical research clinical trial clinician Confusion control group COPD coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 symptom COVID-19 symptoms defined Desaturation disabling symptoms dissemination double-blind Dyspnea effective Efficacy Ethics ethics committee EudraCT evaluate evaluate the effect Exercise capacity exertion explained functional Functional status globe headache Health Health status healthcare include Infection Intervention life Likert scale Long COVID Mental mental confusion Mild mild to moderate moderate Montelukast Mortality objective Open Access oxygen oxygen saturation pandemic participant pathophysiology Patient patients with SARS-CoV-2 peer-reviewed phase Placebo placebo group placebo-controlled primary care Primary outcome professionals Quality of life questionnaire Randomized randomized clinical trial Randomized controlled trial Randomly reference number Registered Research Ethics respiratory respiratory symptom respiratory symptoms SARS-CoV-2 SARS-COV-2 infection Secondary objectives Secondary outcomes sick Side effect Study protocol subgroup of patient Test the SARS-CoV-2 Treatment Trial Trial registration while [DOI] 10.1186/s13063-021-05951-w PMC 바로가기 [Article Type] Study Protocol
Outpatient Pulmonary Rehabilitation in Patients with Long COVID Improves Exercise Capacity, Functional Status, Dyspnea, Fatigue, and Quality of LifeObservational Study Published on 2022-01-012022-10-05 Journal: Respiration [Category] 임상, [키워드] acute respiratory syndrome age assessment average baseline benefit Borg breathlessness Capacity changes in conducted consecutive patient coronavirus Coronavirus disease 2019 COVID COVID-19 COVID-19 patient diffusion capacity disease Dyspnea Endpoint exercise Exercise capacity Exercise training expiratory fatigue functional Functional status Future impairment improvement Infection IQR life limitations Long Long coronavirus disease lung median Outpatient Patient primary endpoint prospective observational cohort protocol pulmonary pulmonary function parameter Pulmonary function test pulmonary rehabilitation Quality Quality of life rehabilitation reported risk scale secondary secondary endpoint Sequelae severe acute respiratory syndrome coronavirus 2 significantly increased survivor Symptom Volume women [DOI] 10.1159/000522118 PMC 바로가기 [Article Type] Observational Study
Predictors of Prolonged Cardiopulmonary Exercise Impairment After COVID-19 Infection: A Prospective Observational StudyMedicine Published on 2021-12-242022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome addition adjusted affected affecting age Asymptomatic BMI body mass index cardiopulmonary exercise testing contributed control group coronavirus Coronavirus disease 2019 CoV COVID-19 COVID-19 diagnosis CPET creatinine kinase Evidence exercise Exercise capacity Exercise limitation explained global pandemic impairment implication individual Infection intensive care Linear regression analysis Lung function Male sex Mild Mild symptom moderate Multiple negatively affected NT-proBNP oxygen uptake Patient patients performed physical predicted Prolonged Prospective prospective observational study R 2 reduced rehabilitation Result SARS-CoV-2 Severe case severe COVID-19 severity Sex significantly Skeletal muscle Ventilation [DOI] 10.3389/fmed.2021.773788 PMC 바로가기 [Article Type] Medicine
Modulatory Effects of Physical Activity Levels on Immune Responses and General Clinical Functions in Adult Patients with Mild to Moderate SARS-CoV-2 Infections—A Protocol for an Observational Prospective Follow-Up Investigation: Fit-COVID-19 StudyProtocol Published on 2021-12-162022-10-04 Journal: International Journal of Environmental Research an [Category] SARS, 임상, [키워드] activity Adipose tissue analyzed approach baseline Biochemistry Blood blood sample body composition clinical collected conducted Control coronavirus coronavirus disease COVID-19 cytokine profile determine Effect evaluated Evidence exercise Exercise capacity explain expressed function functional healthy help homologous immune Immunity immunomodulatory in-vitro assay inactive individual Infection Inflammation Inflammatory information innate immune system knowledge Level long-COVID mechanism Mental mental health metabolic parameters metabolism Mild Moderate COVID-19 mononuclear cell obese participant Patient patients with COVID-19 PBMC PBMCs peripheral phenotypic physical physical activity physical activity level physically positive procedure Prospective prospective observational cohort provided Pulmonary function registry repeated-measures ANOVA Respiratory muscle strength respond response SARS-CoV-2 SARS-COV-2 infection Seahorse serum stimulated survival the SARS-CoV-2 virus the vaccine Trajectories treated vaccination venous viral infection virus [DOI] 10.3390/ijerph182413249 PMC 바로가기 [Article Type] Protocol
Subclinical Myocardial Dysfunction in Patients Recovered from COVID-19 Disease: Correlation with Exercise CapacityArticle Published on 2021-11-182022-10-28 Journal: Biology [Category] COVID-19, [키워드] abnormality age Capacity chest pain clinical Complication consecutive patient control patients correlation COVID-19 COVID-19 disease COVID-19 infection COVID-19 patients diastolic Dyspnea echocardiographic parameters Ejection fraction examined exercise Exercise capacity GLS groups identify longitudinal Myocardial strain no difference Patient patients performed prolong COVID-19 recovered Research risk factor severe disease significantly lower simple strain stress echocardiography Subclinical Symptom Symptoms the disease Treatment ventricular were assessed [DOI] 10.3390/biology10111201 PMC 바로가기 [Article Type] Article
Six-month outcomes and effect of pulmonary rehabilitation among patients hospitalized with COVID-19: a retrospective cohort studyResearch Article Published on 2021-11-122022-10-28 Journal: Annals of Medicine [Category] COVID-19, SARS, [키워드] adjusted affecting age Analysis assigned Biomarker blood chemistry CD4+ T cell changed changes in China confounders control group covariate COVID-19 COVID-19 hospitalization COVID-19 patient disease Effect evaluated exercise Exercise capacity FIVE Follow-up greater groups Health IgM Immunity immunoglobulins immunology increase in investigated maintain majority male outcome Patient patients patients hospitalized performed physical Primary outcome promote pulmonary rehabilitation ranged rehabilitation Respiration Result retrospective cohort retrospective cohort study SARS-CoV-2 SARS-CoV-2 IgG secondary significantly Standard deviation T-lymphocyte variable [DOI] 10.1080/07853890.2021.2001043 PMC 바로가기 [Article Type] Research Article
Measures of physical performance in COVID-19 patients: a mapping reviewCOVID-19 환자의 신체 기능 측정: 매핑 검토Review Published on 2021-11-012022-09-11 Journal: Pulmonology [Category] 임상, [키워드] 6MWT Abstract abstracts activity article articles assessment tool assessments Barthel Index battery CINAHL Cohort comparison Comparisons conducted Consensus Controlled trial COVID-19 COVID-19 infection COVID-19 patients cross-sectional Cross-sectional studies database Desaturation discrepancies distance Dyspnoea English language evaluated Evidence evidence of exercise Exercise capacity Exercise induced desaturation Exercise tests fatigue functional Functional status impairment inclusion criteria Infection investigator measure Measures median NIH observational studies observational study Other Pain patients patients with COVID-19 performance physical protocol Randomized controlled trial ranged rehabilitation reported resolved Sample sample sizes scored screened searched secondary Symptom Symptoms target Test variety verification walking [DOI] 10.1016/j.pulmoe.2021.06.005 PMC 바로가기 [Article Type] Review
COVID-19 in lung transplant recipients—Risk prediction and outcomesResearch Article Published on 2021-10-062022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] analyzed Clinical outcome clinical outcomes Comorbidities Comorbidity COVID-19 Depression died disease Exercise capacity Follow-up Follow-up visit hazard Hospitalized Impact Infection infections knowledge life-threatening lung lung transplant Mortality outcome outcomes pandemic parameter Patient patient population physical predict predicted predictor psychological health Quality of life recipient recipients regression models remained Retrospective analysis risk survival survivor Survivors Treatment was performed were assessed [DOI] 10.1371/journal.pone.0257807 PMC 바로가기 [Article Type] Research Article
Effectiveness of Pulmonary Rehabilitation in Interstitial Lung Disease, Including Coronavirus Diseases: A Systematic Review and Meta-analysis코로나바이러스 질환을 포함한 간질성 폐질환에서 폐재활의 효과: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-10-012022-09-11 Journal: Archives of physical medicine and rehabilitation [Category] SARS, 임상, [키워드] 95% CI 95% confidence interval analyses association baseline Bia caused Cochrane Library conducted coronavirus coronavirus disease Coronavirus disease 2019 Coronaviruses COVID-19 data extraction determine Dyspnea effect size effective eligible evaluated Evidence Exercise capacity fibrosis forced vital capacity functional functional capacity FVC Health identify IMPROVE Improvements inception Including Interstitial lung disease Interstitial lung diseases Intervention life Lung disease Lung function medRxiv Meta-analysis Patient patients predicted pulmonary pulmonary fibrosis pulmonary rehabilitation Quality of life Randomized controlled trial Randomized controlled trials RCT RCTs rehabilitation remained Result review RoB SARS virus searched Sensitivity analyses Support therapeutic strategy vital capacity Web of Science [DOI] 10.1016/j.apmr.2021.03.035 PMC 바로가기 [Article Type] Meta-Analysis
Severity does not impact on exercise capacity in COVID-19 survivorsObservational Study Published on 2021-10-012022-10-04 Journal: Respiratory medicine [Category] 임상, [키워드] acute COVID-19 acute illness addition Cardiopulmonary Cardiopulmonary exercise test Chest computed tomography clinically cohort study comparable COVID-19 Critical disease discharge Efficiency enrolled evaluated Exercise capacity follow-up time group groups interquartile range IQR limit mechanism mild-to-moderate disease outcomes oxygen Patient post-hoc analysis predicted preserved pulmonary Pulmonary function testing reduced severe disease severity Standard deviation survivor Survivors the median Ventilation ventilatory [DOI] 10.1016/j.rmed.2021.106577 PMC 바로가기 [Article Type] Observational Study