Boosting test-efficiency by pooled testing for SARS-CoV-2—Formula for optimal pool sizeResearch Article Published on 2020-11-042022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] amplify benefit COVID19 Efficiency expected False negative rate Healthcare system IMPROVE Infection infection level infections National PCR tests reduce replicate replicates SARS-CoV-2 infections tested [DOI] 10.1371/journal.pone.0240652 PMC 바로가기 [Article Type] Research Article
Nasal lavage containing Angiotensin-Converting Enzyme-2 agonist can prevent and reduce viral load in COVID-19Angiotensin-Converting Enzyme-2 agonist를 함유한 비강 세척은 COVID-19의 바이러스 부하를 예방하고 감소시킬 수 있습니다Article Published on 2020-11-012022-09-11 Journal: Medical Hypotheses [Category] SARS, 치료제, [키워드] ACE inhibitor ACE inhibitors angiotensin angiotensin converting enzyme angiotensin receptor blocker Angiotensin receptor blockers Angiotensin-converting enzyme angiotensin-converting enzyme-2 Anosmia ARBs binding can be used Chain Reaction changes in conditions COVID-19 COVID-19 negative Critical Diagnosis Dilution dosage Efficacy enzyme evaluated False negative False negative rate Formulation heart rate high risk high risk patients hypothese hypotheses include infect cells low blood pressure management medicated medication mode mucosa nasal Nasal lavage nasal mucosa nasal symptom olfactory Olfactory pathway Patient patients PCR penetrate polymerase chain polymerase chain reaction positive patients Potential Prevent raise receptor Receptor Blockers receptors reduce report reported SARS-CoV-2 SARSCoV-2 secondary to Side effect suspicion Symptom trials Vaccine Viral Viral load water [DOI] 10.1016/j.mehy.2020.110207 PMC 바로가기 [Article Type] Article
Direct Clinical Evidence Recommending the Use of Proteinase K or Dithiothreitol to Pretreat Sputum for Detection of SARS-CoV-2Medicine Published on 2020-09-182022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] clinical Clinical practice comparable COVID-19 detect detection detection of SARS-CoV-2 detection rate diagnosing Direct Diseases dithiothreitol DTT Evidence facilitate False negative rate False positive help homogenization IMPROVE nasal non-COVID-19 patient nucleic acid Patient performed pharyngeal proteinase proteinase K (PK) reagent respiratory specimen respiratory specimens RT-PCR SARS-CoV-2 SARS-CoV-2 detection specimen sputum Sputum sample swabs treated Treatment upper respiratory while [DOI] 10.3389/fmed.2020.549860 PMC 바로가기 [Article Type] Medicine
Detection and analysis of nucleic acid in various biological samples of COVID-19 patientsCorrespondence Published on 2020-09-012022-10-05 Journal: Travel medicine and infectious disease [Category] SARS, 치료기술, [키워드] 2019-nCoV Accuracy Admission age anal swab Analysis average biological sample biological samples Blood caused center China Chinese city clinical manifestations Clinical treatment collected confirmed COVID-19 case Control country COVID-19 COVID-19 case COVID-19 patient Critical detection diagnosed with COVID-19 Diagnosis diagnosis of COVID-19 diagnostic digestive tract East epidemiological evaluate False negative rate females gold standard hospital IMPROVE Infection Infectious disease Internal control Isolation Laboratory male Mild Nasopharyngeal swab nasopharyngeal swabs negative control Novel coronavirus infection nucleic acid Nucleic acid detection nucleic acid test observation outbreak Patient patients with COVID-19 performed polymerase chain positive positive rate prevention Program Quantitative reduce Renmin Hospital Result RT-PCR detection RT-PCR test RT-PCR testing sealed Section Sequencing severe pneumonia simple spread to sputum swabs therapeutic effect transcriptase transferred Treatment Trial university upper respiratory tract viral nucleic acid Virus Disease was used Wuhan [DOI] 10.1016/j.tmaid.2020.101673 [Article Type] Correspondence
Diagnosis of COVID-19: Considerations, controversies and challengesResearch Published on 2020-04-212022-10-28 Journal: African Journal of Thoracic and Critical Care Medicine [Category] COVID-19, [키워드] acute respiratory syndrome Antibody Response benefit Biomarker confirmed case coronavirus Coronavirus disease 2019 COVID-19 deaths detect detectable Diagnosis disease employment evaluated False negative rate global pandemic IgM and IgG immunoassay immunoassays individual investigated majority Mild nasopharyngeal sample onset of symptoms Patient Pneumonia polymerase chain positive Rapid required resolution of symptoms robust antibody response RT-PCR SARS-CoV-2 Surveillance symptomatic cases symptomatic disease Symptoms the disease Transcription upper respiratory tract vaccination Viral antigen virus with mild disease [DOI] 10.7196/AJTCCM.2020.v26i2.099 PMC 바로가기 [Article Type] Research