Precision medicine in the era of potent antiviral therapy for chronic hepatitis BReview Published on 2022-07-012023-06-13 Journal: Journal of gastroenterology and hepatology [Category] B형 간염, [키워드] alcohol Comorbidity Fatty liver Hepatitis B, chronic metabolic risk nonalcoholic fatty liver precision medicine [DOI] 10.1111/jgh.15856 [Article Type] Review
Impact of Physical Activity Differences Due to COVID-19 Pandemic Lockdown on Non-Alcoholic Fatty Liver Parameters in Adults with Metabolic Syndrome대사 증후군이 있는 성인의 비알코올성 지방간 매개변수에 대한 COVID-19 유행성 폐쇄로 인한 신체 활동 차이의 영향Article Published on 2022-06-082022-09-11 Journal: Nutrients [Category] 임상, [키워드] activity affected Analysis blood collection Characteristics cholesterol COVID-19 COVID-19 lockdown COVID-19 pandemic decrease difference disease Efficiency Fatty liver fatty liver disease fitness functional group groups HDL-cholesterol healthy Impact IMPROVE inactive intensity lockdown longitudinal magnetic resonance imaging Mediterranean diet Mediterranean lifestyle medium metabolic metabolic syndrome moderate motivation MRI NAFLD Non-alcoholic fatty liver disease parallel-group parameter participant Patient per day physical activity progression questionnaire randomized trial Stopping syndrome were assessed worsening [DOI] 10.3390/nu14122370 PMC 바로가기 [Article Type] Article
Effects of exercise on NAFLD using non-targeted metabolomics in adipose tissue, plasma, urine, and stool Research Published on 2022-04-202022-10-05 Journal: Scientific Reports [Category] 바이오마커, [키워드] addition adipose Amino acid amino acid metabolism Analysis applied baseline benefit bile acid change changes clinical parameter Concentration control group correlated Critical derivative dietary change disease Effect Endpoint Exercise intervention Fatty liver Glucose highlight Human identify Intervention intervention group Lipid Liver disease maximum oxygen consumption mechanism metabolic pathway metabolite metabolomics NAFLD participant participated Patient performed plasma profile provided Randomized significantly Stool subject tissue Urine Waist circumference was used weight loss [DOI] 10.1038/s41598-022-10481-9 [Article Type] Research
Assessing causal relationships between COVID-19 and non-alcoholic fatty liver diseaseCorrespondence Published on 2022-03-012022-10-05 Journal: Journal of hepatology [Category] SARS, 유전자 메커니즘, [키워드] Assessing causal relationship COVID-19 disease Fatty liver [DOI] 10.1016/j.jhep.2021.11.014 [Article Type] Correspondence
A global picture: therapeutic perspectives for COVID-19글로벌 그림: COVID-19에 대한 치료적 관점Review Published on 2022-02-212022-09-10 Journal: Immunotherapy [Category] COVID19(2023년), MERS, SARS, 신약개발, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 affected age cause Complication Consequences Coronary heart disease coronavirus coronavirus disease Coronavirus-2 COVID-19 COVID-19 pandemic determine disorder drug drug discovery process drug dose Drug repurposing drug target event fatty Fatty liver heart disease illness include information life cycle management Metabolic disorders Numerous outbreak overweight pandemic patients Perspective pulmonary disease recovered patients renal renal failure Repurposed drug Repurposed drugs Research research and development respiratory SARS-CoV-2 serious COVID-19 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 subsequent the disease therapeutic therapeutic agent therapeutic agents treat Vaccine Vaccine development Vaccines Viral Viral transmission virus [DOI] 10.2217/imt-2021-0168 PMC 바로가기 [Article Type] Review
The hypertriglyceridemic waist phenotype is associated with fatty liver and glycometabolic profiles in overweight and obese adults: a cross-sectional studyArticle Published on 2022-02-142022-10-04 Journal: Scientific Reports [Category] 바이오마커, [키워드] adjusted Adults age assessment blood pressure BMI body mass index Chinese cross-sectional disorders elevated Fatty liver females gastroenterology glycosylated hemoglobin hepatology high risk highest identify individual insulin LDL Low-Density Lipoprotein cholesterol male metabolic syndrome Model obese obesity overweight/obese participant phenotype profile resistance risk significantly higher Standard deviation Triglyceride Waist circumference [DOI] 10.1038/s41598-021-00825-2 PMC 바로가기 [Article Type] Article
Fatty liver on computed tomography scan on admission is a risk factor for severe coronavirus disease입원 시 컴퓨터 단층 촬영에서 지방간은 심각한 코로나 바이러스 질병의 위험 요소입니다Article Published on 2022-02-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 치료기술, [키워드] Admission alleviate Asymptomatic Care clinician Computed tomography coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 guidelines COVID-19 patient COVID-19 patients COVID-19 severity criteria CT scan evaluate evaluated Factor Fatty liver groups had no help hospital hospitals invasive Japanese less liver Logistic regression analysis median median age Mild moderate multivariate multivariate logistic regression analysis occurred outcome overflow Patient patients performed Pneumonia required retrospective cohort study risk factor severe coronavirus disease severe COVID-19 significantly Triage was performed [DOI] 10.1016/j.jiac.2021.10.013 PMC 바로가기 [Article Type] Article
Interaction between Lifestyle Changes and PNPLA3 Genotype in NAFLD Patients during the COVID-19 LockdownArticle Published on 2022-01-272022-10-30 Journal: Nutrients [Category] COVID-19, SARS, [키워드] age Analysis change changed changes in Cohort collected coronavirus disease COVID-19 diet disease enrolled evaluate Fatty liver Features Genotype genotyping glycemia hepatic disease independent risk factor information Italy laboratory data lockdown Mediterranean diet NAFLD NAFLD patient Patient Patient care patients Perspective physical activity PNPLA3 Prevalence reduced remained risk factor SARS-CoV-2 Seven Sex steatosis transaminase was performed weight gain worsened worsening [DOI] 10.3390/nu14030556 PMC 바로가기 [Article Type] Article
Metabolic biomarkers related to cardiac dysfunction in metabolic-dysfunction-associated fatty liver disease: a cross-sectional analysisArticle Published on 2022-01-182022-10-04 Journal: Nutrition & Diabetes [Category] 바이오마커, [키워드] 95% CI age Analysis average Biomarker cardiac cardiovascular diseases cardiovascular risk Cer ceramide conducted confounding factor confounding factors controls correlated cross-sectional cross-sectional analysis Decreased diastolic disease distribution dysfunction Effect Ejection fraction Endocrine system and metabolic diseases evaluated Fatty liver females Gender GLS hepatic IQR LVEF male material median age metabolic metabolite Multiple linear regression P -value participant Patient reduced remained Result risk significantly steatosis tyrosine ventricular [DOI] 10.1038/s41387-022-00182-7 PMC 바로가기 [Article Type] Article
Paternally expressed gene 3 ( Pw1/Peg3 ) promotes sexual dimorphism in metabolism and behavior친밀하게 발현 된 유전자 3 (PW1/PEG3)은 신진 대사와 행동에서 성 이형성을 촉진합니다Research Article Published on 2022-01-132022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accelerated Adiposity adulthood age allele alteration Behavior Brain Cell cells Characteristics consequence contribute develop Diabetic Endocrine Epigenetic examined expressed expressing fat accumulation Fatty liver female genomic genomic imprinting gonadal growth hormone insulin insulin resistance life loss of function male mammal mammals manifested masculinization metabolism mice mutant observation parental pathway Peg3 phenotypic postnatal development proliferative promote provide puberty question reduced Regulation selective Sex sex steroid sexual dimorphism Signaling steroid Support tissues weaning [DOI] 10.1371/journal.pgen.1010003 PMC 바로가기 [Article Type] Research Article