free radical – Page 3 – Communicable Diseases Research

Effects of Antimalarial Drugs on Neuroinflammation-Potential Use for Treatment of COVID-19-Related Neurologic Complications

Article

Published on 2020-09-082022-10-30
Journal: Molecular neurobiology [Category] COVID-19, MERS, SARS,

[키워드] activated addition Affect affecting Aminoacridine anti-inflammatory agents Anti-inflammatory drugs antimalarial Antimalarials Aortic body arachidonic acid blood vessels Brain endothelial cells carotid body Cell culture Central nervous system Chloroquine clinical trial CNS combating Complication coronavirus coronavirus disease Coronavirus replication COVID COVID-19 COX cPLA₂ cross cytokine Cytokine storm cytosolic Cytosolic phospholipase A₂ Dementia disorder DMT1 drug Effect Eicosanoids ENhance expression free radical Free radical damage free radical formation generate Glossopharyngeal nerve hippocampus Hydroxychloroquine Hypoxemia impair induce Inflammation Inflammatory response inhibit inhibiting inhibition inhibitor iron accumulation Iron transport isoform isoforms lung lysosomal enzymes lysosome Lysosomes mice Microcirculation microglia Microvessels Neuroinflammation Neurovascular Nucleus of the tractus solitarius organ oxidative damage oxidative stress PLA2G2D pro-inflammatory produced quinacrine reducing Respiratory centre resulting SARS SARS-CoV SARS-CoV-2 SARS-CoV-2 virus Secretory phospholipase A₂ Seizures severe cases shown silent sPLA₂ IID statins stroke the SARS-CoV-2 virus tissue TNF-α Treatment unique vagus nerve Vascular vascular dementia viral replication
[DOI] 10.1007/s12035-020-02093-z PMC 바로가기 [Article Type] Article

Is Antioxidant Therapy a Useful Complementary Measure for Covid-19 Treatment? An Algorithm for Its Application

Review

Published on 2020-07-312022-10-30
Journal: Medicina [Category] COVID-19, SARS,

[키워드] accompanied ACE2 receptor Activation acute lung injury acute respiratory distress alveolar antioxidant antioxidant therapy application bind cause cells Characteristics cleavage Comorbidity consequence contribute coronavirus 2 COVID-19 Critical cytokine cytokine production Cytokine storm cytotoxicity death rate distress drug elevated ENhance enzyme eosinophil free radical Genes help hospital Host illness immune response IMPROVE Inflammation Inflammatory response intensive care leukocyte lung Macrophage measure mechanical ventilation mechanism mechanism of action membrane Monocytes mortality rate multiple organ dysfunction Neutrophils NFkB Organ failure oxidative stress Oxidizing agent oxygen exchange Oxygenation Pathogenesis Patient phagocytic promote protease receptor reduce Release respiratory SARS-CoV-2 Sepsis severe pneumonia Stress syndrome tested the SARS-CoV-2 therapeutic therapy tissue Transcription Transmissibility virus
[DOI] 10.3390/medicina56080386 PMC 바로가기 [Article Type] Review