Cord blood antibody following maternal SARS-CoV-2 inactive vaccine (CoronaVac) administration during the pregnancy임신 중 산모의 SARS-CoV-2 불활성 백신(CoronaVac) 투여 후 제대혈 항체Article Published on 2021-10-032022-09-11 Journal: Human vaccines & immunotherapeutics [Category] SARS, 치료기술, [키워드] administration adverse event adverse events age anti-RBD anti-receptor-binding domain antibodies antibody arbitrary unit Beijing Birth Birth weight Blood Care China Cord blood CoronaVac detectable Efficacy first dose first identified case gestation gestational age HCW Health Health care healthy IgG antibodies inactivated inactive life Maternal mother Newborn placental Pregnancy RBD reported SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibodies SARS-CoV-2 IgG antibody SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 vaccine SARS-CoV-2 vaccines Science second dose sera Sinovac Spike protein the vaccine transfer vaccination Vaccine virus [DOI] 10.1080/21645515.2021.1947099 PMC 바로가기 [Article Type] Article
Assessment of an intervention to optimise antenatal management of women admitted with preterm labour and intact membranes using amniocentesis-based predictive risk models: study protocol for a randomised controlled trial (OPTIM-PTL Study)양수천자 기반 예측 위험 모델을 사용하여 조산 및 온전한 막으로 입원한 여성의 산전 관리를 최적화하기 위한 중재 평가: 무작위 대조 시험을 위한 연구 프로토콜(OPTIM-PTL 연구)Article Published on 2021-09-282022-09-11 Journal: BMJ Open [Category] SARS, 임상, [키워드] 24 hour 24 hours added age All participant All participants Amniocentesis amniotic Amniotic cavity Analysis Antenatal Antibiotic therapy Antibiotics approval approved assessment authority Care chorioamnionitis clinical clinical trial conducted control group Corticosteroid Corticosteroids Cost analysis database Device doses doses of corticosteroids dropout rate drug eligible patient Ethics ethics committee EudraCT European European Union Drug Regulating Authorities Clinical Trials database evaluated fetal fetal medicine finding gestational age high risk highest hospital discharge Hospital stay identification identification number institutional protocols Intervention intervention arm Invasion majority management maternal medicine Medical devices medication Medicine Medicines membrane microbial multicentre observé Occurrence overtreatment peer-reviewed power power of 80% Predictive Pregnancy Primary outcome randomisation randomised randomised controlled trial receiving reducing reduction reduction in Registered Regulating required risk secondary outcome Secondary outcomes Spanish stratified Study protocol Trial two-sided type I type I error Ultrasonography union while women written Informed Consent [DOI] 10.1136/bmjopen-2021-054711 PMC 바로가기 [Article Type] Article
Weekly 17 alpha-hydroxyprogesterone caproate to prevent preterm birth among women living with HIV: a randomised, double-blind, placebo-controlled trial주간 17 Alpha-HydroxyProgesterone CABROATE HIV를 가진 여성들 사이에서 조산을 예방하기위한 : 무작위, 이중 맹검, 위약 대조 시험Articles Published on 2021-09-092022-09-06 Journal: The Lancet. HIV [Category] Communicable Disease, [키워드] 1:1 17P 95% CI adherence adverse event adverse events age Anomaly antenatal care Antiretroviral therapy assessments assigned available data baseline characteristics both groups Cervical cerclage Characteristics Complete Composite criteria District double-blind drug during pregnancy early delivery Eligible participants eligible patient Eligible patients enrolled event Evidence evidence of except for exclusion criteria fetal Final finding Follow-up for inclusion foundation funding gestation gestational age group groups HIV infection HIV-1 infection in both groups in some increased risk injection Intention intention to treat intramuscular investigated less Melinda Gate Melinda Gates membrane miscarriage occurred Older participant Participants Patient Placebo placebo-controlled trial Pregnancy pregnant women Preterm birth Prevent Primary outcome proportion provided random assignment randomisation randomised Randomly receive receiving reduce Registered Relative risk reported risk risk difference Safe Serious Adverse Event Serious Adverse Events shown Stillbirth study drug Support Teaching treatment group treatment groups Trial university uterine Weekly were excluded with HIV women written Informed Consent [DOI] 10.1016/S2352-3018(21)00150-8 PMC 바로가기 [Article Type] Articles
The COVID-19 pandemic and reproductive genetic counseling: Changes in access and service delivery at an academic medical center in the United StatesCOVID-19 범유행과 생식 유전자 상담: 미국 학술 의료 센터의 접근 및 서비스 전달의 변화Article Published on 2021-08-012022-09-11 Journal: Journal of genetic counseling [Category] 유전자 메커니즘, [키워드] 95% CI age Appointment Care cell-free DNA change clinic Complete continuity Continuity of care counseling COVID-19 COVID-19 pandemic demographics FIVE Frame Future Genetic Genetic counseling genetic counselors genetic screening genetic services gestational age global pandemic healthcare services indication large academic medical center no significant difference Patient patient age populations prenatal prenatal genetic counseling reproductive sample collection service delivery models significant difference Support telehealth Telemedicine the United State Time frame transitioned United States [DOI] 10.1002/jgc4.1462 PMC 바로가기 [Article Type] Article
Safety of tocilizumab in COVID-19 pregnant women and their newborn: A retrospective studyCOVID-19 임산부와 신생아에서 토실리주맙의 안전성: 후향적 연구Multicenter Study Published on 2021-08-012022-09-11 Journal: Journal of clinical pharmacy and therapeutics [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Admission adverse event adverse events age Algorithm Azithromycin Beta candidate close monitoring collected Coronavirus-2 Corticosteroid Corticosteroids COVID-19 cytomegalovirus demographics detrimental effect detrimental effects discharge during pregnancy electronic medical records Evolution gestational age hepatotoxicity hospital hospitals Hydroxychloroquine IL-6 IL-6 receptor Infection inflammatory phase information inhibitor interferon interferon beta interquartile range laboratory data Lopinavir Lopinavir/ritonavir maternal safety medical history MOST mother Neonatal Newborn newborn safety other immunosuppressive agent other immunosuppressive agents outcome Patient patients Pregnancy pregnant women radiologic resolved respiratory Result Retrospective study Ritonavir Safety SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe COVID-19 Spanish Tocilizumab tocilizumab administration treated Treatment two patients Viral viral reactivation [DOI] 10.1111/jcpt.13394 PMC 바로가기 [Article Type] Multicenter Study
BCG-induced non-specific effects on heterologous infectious disease in Ugandan neonates: an investigator-blind randomised controlled trial우간다 신생아의 이종 감염성 질환에 대한 BCG- 유도 비특이적 영향 : 조사관 맹인 무작위 대조 시험Articles Published on 2021-07-012022-09-06 Journal: The Lancet. Infectious Diseases [Category] Communicable Disease, [키워드] 1:1 Abstract addition age all-cause mortality Alter analysed analyses assigned BCG BCG vaccination benefit Birth blind block size block sizes blood sample Blood samples change clinically clinician Comparisons computer-generated Concentration Consent contributed Controlled Controlled trial Cord blood discharged Effect Effects eligible enrolled Entebbe Families finding Follow-up for inclusion funding geometric geometric mean geometric mean ratios gestational age group hazard ratio healthy hepcidin Heterologous hospital IFNγ IL-10 IL-1β IL-6 IL1B IL6 immunological incidence increase in Infant Infants infections Infectious disease inhibited Innate immunity international standard investigated investigators life Luganda material medical intervention modified intention-to-treat mononuclear cell morbidity morbidity and mortality mother Neonatal neonatal period no significant difference non-specific number outcome parent parents participant Peripheral blood Peripheral blood mononuclear cells primary clinical outcome promoter promoter region PROTECT randomisation randomised randomised controlled trial Randomly receive recruited reduce reductions reductions in Registered required saturation Standard Standard dose stratified by sex TNF Transferrin translation Trial Tuberculosis Uganda vaccination Wellcome Trust were excluded with HIV withdrawn [DOI] 10.1016/S1473-3099(20)30653-8 PMC 바로가기 [Article Type] Articles
Sleep Apnea and Fetal Growth Restriction (SAFER) study: protocol for a pragmatic randomised clinical trial of positive airway pressure as an antenatal therapy for fetal growth restriction in maternal obstructive sleep apnoea수면 무호흡증 및 태아 성장 제한(SAFER) 연구: 산모 폐쇄성 수면 무호흡증의 태아 성장 제한에 대한 산전 요법으로서 기도 양압에 대한 실용적인 무작위 임상 시험 프로토콜Article Published on 2021-06-292022-09-11 Journal: BMJ Open [Category] SARS, 임상, [키워드] Admission age Anomaly Antenatal APGAR score approved Birth weight Care cause center clinical trial complications Controlled trial COVID-19 Desaturation enrolment Ethics fetal FGR gestation gestational age growth hypothesise IMPROVE include institutional review board institutional review boards intensive care intention-to-treat analysis intrauterine infection Jerusalem maternal medicine morbidity and mortality mother multicentre Neonatal neonatal intensive care unit New York Obstructive obstructive sleep apnoea OSA outcome outcomes oxygen participant perinatology positive airway pressure Pragmatic pregnancies Pregnancy pregnant women Primary outcome proceed protocol questionnaire randomised registration number restriction risk risk factor screened second trimester secondary outcome Secondary outcomes Sleep sleep apnea sleep apnoea Sleep medicine Stage stage 2 standard care Stillbirth therapy Treatment Ultrasound undergo university Washington [DOI] 10.1136/bmjopen-2021-049120 PMC 바로가기 [Article Type] Article
Pregnancy Outcome, Antibodies, and Placental Pathology in SARS-CoV-2 Infection during Early Pregnancy임신 초기 SARS-CoV-2 감염의 임신 결과, 항체 및 태반 병리학Article Published on 2021-05-262022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, [키워드] age amniotic Amniotic fluid Antibody testing Blood Chain Reaction Complication Cord blood COVID-19 COVID-19 antibody diagnosed during pregnancy early pregnancy evaluated Evidence evidence of fetal fetus first trimester first trimester pregnancy FIVE gestational age IgG antibodies IgG antibody IgM and IgG Immunity infected with SARS-CoV-2 inflammatory change inflammatory changes maternal antibodies maternal antibody maternal blood maternal plasma morbidity neutralizing antibody outcome pathology Placenta placental Placentas polymerase chain polymerase chain reaction positive Pregnancy pregnant women Retrospective study reverse transcription reverse transcription polymerase chain reaction SARS-CoV-2 SARS-COV-2 infection Seven Vascular vertical infection transmission were infected women [DOI] 10.3390/ijerph18115709 PMC 바로가기 [Article Type] Article
Available medications used as potential therapeutics for COVID-19: What are the known safety profiles in pregnancyCOVID-19의 잠재적 치료제로 사용 가능한 약물: 임신 중 알려진 안전성 프로파일은 무엇입니까?Research Article Published on 2021-05-192022-09-10 Journal: PLoS ONE [Category] SARS, 신약개발, 치료제, [키워드] 95%CI Adjusting age angiotensin ARB Azithromycin Birth weight blocker caution Chloroquine clinical trial clinical trials condition confounder confounders congenital malformation COVID-19 Dexamethasone during pregnancy eligible excluded exposure to gestational age gestational period heparin heparins HIV Hydroxychloroquine increased risk indication indications interferon interferons LBW Low birth weight medication medications oseltamivir outcomes Potential treatment potential treatments pregnancies Pregnancy pregnant women Prematurity quantified Result risk safety profile Taking treat treatments for COVID-19 trials unique with COVID-19 women [DOI] 10.1371/journal.pone.0251746 PMC 바로가기 [Article Type] Research Article
Characteristics, clinical and laboratory data and outcomes of pregnant women with confirmed SARS-CoV-2 infection admitted to Al-Zahra tertiary referral maternity center in Iran: a case series of 24 patients이란 Al-Zahra 3차 의뢰 산부인과 센터에 입원한 SARS-CoV-2 감염 확인된 임산부의 특성, 임상 및 실험실 데이터 및 결과: 24명의 환자에 대한 일련의 사례Case Report Published on 2021-05-172022-09-01 Journal: BMC Pregnancy and Childbirth [Category] 진단, [키워드] abortion age Anosmia approved Asymptomatic case Asymptomatic cases Blood Group Blood pH Caesarean section Case series case sery change clinical clinical record clinical records clinical symptom Clinical symptoms complications cough COVID-19 COVID-19 complications diagnosis of COVID-19 diarrhea during pregnancy Dyspnea ethics committee evaluate Evidence evidence of Fever finding form gestational age greater healthy HELLP syndrome higher risk hospital Hospitalized hypertension immaturity indication Infection Iran Laboratory laboratory characteristics laboratory data lymphopenia maternity hospital morbidity and mortality myalgia Neonatal Neonate Newborn NICU NICU admission no evidence of no increase normal range nulliparous Obstetric outcome oxygen oxygen saturation Patient Pharyngeal swab Placenta pregnancies Pregnancy pregnancy complications pregnancy-induced hypertension pregnant patient pregnant patients pregnant women Premature premature labor Prevalence referred to Result risk SARS-COV-2 infection SpO2 Symptom Tabriz term tested Transmission university vertical vertical transmission was performed women [DOI] 10.1186/s12884-021-03764-y PMC 바로가기 [Article Type] Case Report