High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19
420
Published on
Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, MERS, SARS,
Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, MERS, SARS,
[키워드] Activation
acute respiratory syndrome
alteration
basophils
CD63
CD69
circulating
clinical complication
clinical feature
Clinical features
Clinical outcome
collected
combined use
computational modeling
convalescent
convalescent phase
coronavirus
correlated
COVID-19
COVID-19 pandemic
COVID-19 pathogenesis
COVID-19 patient
COVID-19 patients
COVID-19 severity
CXCR4
detrimental
dysregulated
dysregulation
eosinophil
eosinophil and basophil activation
Evidence
expression
flow cytometry
granulocyte
Granulocytic
heterogeneity
high-dimensional flow cytometry
Hospitalization
identify
immature
immune
immune response
immunotype
indicate
inflammatory markers
inflammatory state
innate immune response
involved
laboratory measurement
longitudinal analysis
Migration
Multiorgan dysfunction
neutrophil
neutrophil heterogeneity
Neutrophils
pathophysiologic
Patient
Peripheral blood
phenotypic
phenotypic data
predict
predicted
Predictive
profiles
Protein
provide
receptor
Respiratory function
reveal
SARS-COV-2 infection
selected
severity of COVID-19
Significance
significantly
subset
the disease
viral immune responses
virus clearance
with COVID-19
[DOI] 10.1073/pnas.2109123118 PMC 바로가기 [Article Type] 420
[DOI] 10.1073/pnas.2109123118 PMC 바로가기 [Article Type] 420