First Report of Sarconema eurycerca Heart Infection in Mute Swans in SerbiaCase Reports Published on 2022-12-012023-06-01 Journal: Acta parasitologica [Category] 조류인플루엔자, [키워드] heart Mute swans roundworm Sarconema eurycerca. [DOI] 10.1007/s11686-022-00616-3 [Article Type] Case Reports
Morphological changes without histological myocarditis in hearts of COVID-19 deceased patientsArticle Published on 2022-12-012023-07-09 Journal: Scandinavian cardiovascular journal : SCJ [Category] COVID19(2023년), [키워드] COVID-19 heart hypoxia Inflammation myocarditis [DOI] 10.1080/14017431.2022.2085320
COVID-19 Pathology in the Lung, Kidney, Heart and Brain: The Different Roles of T-Cells, Macrophages, and MicrothrombosisArticle Published on 2022-10-042022-11-15 Journal: Cells [Category] COVID19(2023년), SARS, 진단, [키워드] activated activated macrophages Activation age antibody Autopsy B-lymphocytes Brain change characteristic Clinical course controls COVID-19 COVID-19 case COVID-19 pathology elderly exhibited feature foci greater heart hearts highest Hyperactivation Inflammation Inflammatory kidney kidneys lung lung; Lymphocytes microglial Microthrombosis Neuropathology nine other tissue pathology pathophysiology PCR Platelets predominant role SARS-CoV-2 significantly significantly higher T-lymphocyte T-lymphocytes the disease tissue tissues viral antigens viral replication Viral RNA were used [DOI] 10.3390/cells11193124 PMC 바로가기
Association of Symptoms After COVID-19 Vaccination With Anti-SARS-CoV-2 Antibody Response in the Framingham Heart StudyArticle Published on 2022-10-032022-11-15 Journal: JAMA Network Open [Category] 진단, [키워드] COVID-19 heart response [DOI] 10.1001/jamanetworkopen.2022.37908 PMC 바로가기
Investigating and Resolving Cardiotoxicity Induced by COVID-19 Treatments using Human Pluripotent Stem Cell-Derived Cardiomyocytes and Engineered Heart TissuesArticle Published on 2022-10-012022-11-15 Journal: Advanced Science [Category] 신약개발, 치료제, [키워드] antiviral drugs approved drugs ATP2A2 cardiotoxic effect Cardiotoxicity cell death Clinical data clinical trial clinically concentrations contractile Coronavirus disease 2019 COVID-19 demonstrated drug drug candidate drug treatments dysregulation effective engineered heart tissue evaluate expression of gene fumarate handling HCN4 heart heart tissue High Throughput Screening Human human pluripotent stem cell-derived cardiomyocytes induced ion homeostasis limit MYH6 Patient powerful tool regulate Remdesivir Repurposed drug repurposed drugs for COVID-19. reveal Ritonavir RNA-seq analysis significantly Spread STEM therapy TNNT2 [DOI] 10.1002/advs.202203388 PMC 바로가기
A machine-learning algorithm for diagnosis of multisystem inflammatory syndrome in children and Kawasaki disease in the USA: a retrospective model development and validation studyArticle Published on 2022-10-012022-11-16 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy age Algorithm Boston Care center characteristic Child childhood children clinician collected Connecticut COVID-19 pandemic develop development diagnosed Diagnosis Diego disease distribution Early detection enrolled Eunice Kennedy Shriver External feature febrile febrile illness first stage FIVE foundation group heart hospital hospitals Human illness illnesses Inflammatory initial IQR Kawasaki disease laboratory measurements library Los Angele machine-learning median Medicine MIS-C Patient Prevent retrospective SARS-COV-2 infection severe complications similarity stratified syndrome systemic inflammation Treatment USA validation study Washington [DOI] 10.1016/S2589-7500(22)00149-2 PMC 바로가기
Histologic, viral, and molecular correlates of heart disease in fatal COVID-19Research article Published on 2022-10-012022-10-05 Journal: Annals of diagnostic pathology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] ACE2 expression activated arrhythmia Arrhythmias cardiac connexin 43 Control COVID-19 disease dysfunction edema endocytosed Endothelial cell evidenced experiment expression fatal COVID-19 greater heart heart tissue histologic host response IL6 immunohistochemistry In situ hybridization induce interstitial Macrophage manifestation Migration molecular multifocal myocarditis Myocardium Myocyte nucleocapsid protein obesity perivascular predominant Protein Proteins quantified risk RNA SARS-CoV-2 spike protein SARS-CoV2 severe COVID-19 sodium Spike protein the spike protein tissue TNFα Type II Diabetes unique Viral protein viral spike protein would increase [DOI] 10.1016/j.anndiagpath.2022.151983 [Article Type] Research article
The risk and consequences of breakthrough SARS-CoV-2 infection in solid organ transplant recipients relative to non-immunosuppressed controlsArticle Published on 2022-10-012023-07-09 Journal: American journal of transplantation : official jou [Category] COVID19(2023년), [키워드] allograft type breakthrough cardiac COVID-19 heart Infection kidney liver lung MACE MARCE Mortality outcome SARS-CoV-2 solid organ transplantation vaccination [DOI] 10.1111/ajt.17117 PMC 바로가기
Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19Research article Published on 2022-10-012022-10-05 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 바이오마커, 변종, 유전자 메커니즘, 임상, 진단, 치료기술, [키워드] 95% CI Activation adjusted adjusted odds ratio aggregation Alpha Analysis application B.1.1.7 Bath biochemical Biomarkers biomarkers of inflammation biopsy changes clinical factors clinical outcomes clinically Coagulation Cohort Complication correlation Council COVID-19 death develop Dexamethasone diagnostic Direct driving dysregulation of coagulation Engineering evaluated facilitate finding foundation funding hazard ratio heart hospital identify in-hospital mortality indicated Inflammation investigated mammary marker myocardial injury National Health Service NHS NIHR Non-invasive outcome Oxford parameters Pathways Patient patients with COVID-19 perivascular Platelet platform predict produced Prognostic value pulmonary angiography pulmonary CT representing respond responsible risk RNA sequencing data SARS-CoV-2 variant Science sensitivity analysis targeted therapy therapeutic target transcriptional transcriptomic Treatment Trial validation study variant vascular inflammation Wellcome Trust Whole blood wild-type SARS-CoV-2 with COVID-19 [DOI] 10.1016/S2589-7500(22)00132-7 [Article Type] Research article
Improved immunogenicity following the third dose of BNT162b2 mRNA vaccine in heart transplant recipientsArticle Published on 2022-09-022022-11-15 Journal: European journal of cardio-thoracic surgery : official journal of the [Category] 진단, 치료제, [키워드] acute respiratory syndrome age Anti-spike association baseline BNT162b2 BNT162b2 vaccine booster coronavirus COVID-19 decrease dose General population heart Heart transplantation immunogenicity Immunoglobulin Improved inhibitor inhibitors IQR lack mammalian median age mRNA vaccine non-responder of BNT162b2 oral steroid Patient positive predictor proportion prospective cohort study Rapamycin recipient recipients Responder seropositive Serum level severe acute respiratory syndrome coronavirus 2 significantly significantly increased the median third dose titre U/mL Vaccine [DOI] 10.1093/ejcts/ezac145 PMC 바로가기