In vitro selection of macrocyclic peptide inhibitors containing cyclic γ 2,4 -amino acids targeting the SARS-CoV-2 main proteasearticle Published on 2023-05-222024-09-05 Journal: Nat Chem [Category] update2024, [키워드] High-throughput screening peptides translation X-ray crystallography [DOI] 10.1038/s41557-023-01205-1 PMC 바로가기 [Article Type] article
MasitinibL shows promise as a drug-like analog of masitinib that elicits comparable SARS-Cov-2 3CLpro inhibition with low kinase preferencearticle Published on 2023-04-282024-09-05 Journal: Burma Med J [Category] update2024, [키워드] Computational biology and bioinformatics Drug discovery Drug screening High-throughput screening Virtual screening [DOI] 10.1038/s41598-023-33024-2 PMC 바로가기 [Article Type] article
High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spikearticle Published on 2023-04-102024-09-05 Journal: Nature Communications [Category] update2024, [키워드] High-throughput screening SARS-CoV-2 [DOI] 10.1038/s41467-023-37786-1 PMC 바로가기 [Article Type] article
Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening말라리아 전파를 차단할 수 있는 안전한 약물이 비장 모사 스크리닝을 통해 밝혀졌다.Article Published on 2023-04-072024-08-01 Journal: Nature Communications [Category] 말라리아, [키워드] High-throughput screening Parasite biology [DOI] 10.1038/s41467-023-37359-2 PMC 바로가기
Patients with ACPA-positive and ACPA-negative rheumatoid arthritis show different serological autoantibody repertoires and autoantibody associations with disease activityarticle Published on 2023-04-012024-09-05 Journal: Burma Med J [Category] update2024, [키워드] Autoimmunity bioinformatics Diagnostic markers High-throughput screening Rheumatic diseases Translational research [DOI] 10.1038/s41598-023-32428-4 PMC 바로가기 [Article Type] article
Role of three-dimensional cell culture in therapeutics and diagnostics: an updated reviewReview Article Published on 2023-03-272024-09-05 Journal: Drug delivery and translational research [Category] update2024, [키워드] 2D cell culture Drug testing Drug toxicity screening High-throughput screening Preclinical validation Three-dimensional cell culture models [DOI] 10.1007/s13346-023-01327-6 PMC 바로가기 [Article Type] Review Article
Optimization of a high-throughput nanofluidic real-time PCR to detect and quantify of 15 bacterial species and 92 Streptococcus pneumoniae serotypes15종의 세균과 92종의 폐렴구균 혈청형을 검출하고 정량화하기 위한 고처리량 나노유체 실시간 PCR 최적화Article Published on 2023-03-212024-07-28 Journal: Burma Med J [Category] 폐렴구균 감염증, [키워드] High-throughput screening Infectious diseases Medical research Microbiology techniques Nanobiotechnology Respiratory tract diseases [DOI] 10.1038/s41598-023-31820-4 PMC 바로가기
From a genome-wide screen of RNAi molecules against SARS-CoV-2 to a validated broad-spectrum and potent prophylaxisarticle Published on 2023-03-162024-09-05 Journal: Communications Biology [Category] update2024, [키워드] High-throughput screening RNAi therapy [DOI] 10.1038/s42003-023-04589-5 PMC 바로가기 [Article Type] article
TMPRSS2 and SARS-CoV-2 SPIKE interaction assay for uHTSArticle Published on 2023-03-152024-09-05 Journal: Journal of Molecular Cell Biology [Category] update2024, [키워드] COVID-19 High-throughput screening Protein–protein interaction SARS-CoV-2 spike TMPRSS2 TR-FRET [DOI] 10.1093/jmcb/mjad017 PMC 바로가기 [Article Type] Article
Non-falciparum malaria infection and IgG seroprevalence among children under 15 years in Nigeria, 20182018년 나이지리아 15세 이하 아동의 비팔수파 말라리아 감염 및 IgG 항체 유병률Article Published on 2023-03-132024-08-01 Journal: Nature Communications [Category] 말라리아, [키워드] Diagnostic markers Epidemiology High-throughput screening malaria Policy and public health in microbiology [DOI] 10.1038/s41467-023-37010-0 PMC 바로가기