Quantitative mapping of mRNA 3’ ends in Pseudomonas aeruginosa reveals a pervasive role for premature 3’ end formation in response to azithromycinPseudomonas aeruginosa에서 mRNA 3 '끝의 정량적 매핑은 아지트로 마이신에 대한 반응으로 조기 3'말단 형성에 대한 광범위한 역할을 보여줍니다.Research Article Published on 2021-07-122022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 3’ end accompanied accumulation Alter antibiotic Antibiotics approach Azithromycin azithromycin treatment cause change changes in chronic infection chronic infections clinical outcomes control gene Culture cystic fibrosis downregulated downregulated gene expression fibrosis Gene Expression Gene regulation Genes growth GTPase Hospital-acquired infection hospital-acquired infections hospitalized patient hospitalized patients immunocompromised individuals impair improve clinical outcome incidence Infection involved Macrolide mechanism molecular mechanism molecular mechanisms MOST mRNA nucleases nucleotide P . aeruginosa Patient persistence planktonic Premature promote provide Pseudomonas aeruginosa quorum reduced Regulation regulatory element respond resulting reveal RNA robust Stress stress response subject Support therapeutic intervention thought transcript Transcription transcriptional transcriptional response treated Treatment turn upregulated genes upregulating virulence [DOI] 10.1371/journal.pgen.1009634 PMC 바로가기 [Article Type] Research Article
Immunomodulatory therapy, risk factors and outcomes of hospital-acquired bloodstream infection in patients with severe COVID-19 pneumonia: a Spanish case–control matched multicentre study (BACTCOVID)Original Article Published on 2021-07-072022-11-01 Journal: Clinical microbiology and infection : the official [Category] COVID-19, MERS, [키워드] 1:1 Abstract accounted acute respiratory distress Admission age Analysis Bacteraemia bloodstream BSI caused characteristics of patient Cohort combinations Control Corticosteroids COVID-19 database Enterococcus hazard ratio Hospital-acquired infection Hospitalized hospitalized patient identify Image immunomodulatory drug immunomodulatory therapy in-hospital mortality increased risk Infection IQR median time mortality risk multicentre objective outcome Patient patients patients with COVID-19 performed polymicrobial infection prospective cohort Pseudomonas aeruginosa Result risk risk factor SARS-CoV-2 pneumonia severe COVID-19 Severe COVID-19 pneumonia severity Sex Spanish syndrome therapy time factor Tocilizumab was performed with COVID-19 [DOI] 10.1016/j.cmi.2021.06.041 PMC 바로가기 [Article Type] Original Article
Trends in Nursing Research on Infections: Semantic Network Analysis and Topic ModelingArticle Published on 2021-06-282022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] accumulated article Bacterial infection Bacterial infections conducted country COVID-19 pandemic developmental HIV Hospital-acquired infection immune Infection infection control infections modeling network network analysis Nurse Nurses Nursing Pregnancy Research researchers respiratory infections retrieved semantics text mining Topic transmitted trend urinary tract infections viral infections Web of Science with HIV [DOI] 10.3390/ijerph18136915 PMC 바로가기 [Article Type] Article
Infectious events in patients with severe COVID-19: results of a cohort of patients with high prevalence of underlying immune defectResearch Published on 2021-05-252022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] Analysis antibiotic Bacterial cohort of patient Community Community-acquired infections consecutive patient COVID-19 COVID-19 patient cumulative cumulative incidence cumulative risk Dexamethasone event Factor Frequency fungal had no high risk Hospital-acquired infection hospital-acquired infections ICU immune incidence incidence density Infection infection rate infections intensive care intensive care unit malignancy Mortality organ Patient patients Pneumonia Prevalence Propensity score Result risk factor SARS-CoV-2 severe COVID-19 severity single-center study subset supplementary material use of steroid was performed were used [DOI] 10.1186/s13613-021-00873-x PMC 바로가기 [Article Type] Research
Preventing SARS-CoV-2 transmission in the emergency department by implementing a separate pathway for patients with respiratory conditionsArticle Published on 2021-05-242023-07-06 Journal: Journal of complementary & integrative medicine [Category] COVID19(2023년), [키워드] COVID-19 emergency department Hospital-acquired infection infection control SARS-CoV-2 [DOI] 10.1515/jcim-2020-0422
Impact of early low-calorie low-protein versus standard-calorie standard-protein feeding on outcomes of ventilated adults with shock: design and conduct of a randomised, controlled, multicentre, open-label, parallel-group trial (NUTRIREA-3)Randomized Controlled Trial Published on 2021-05-112022-10-05 Journal: BMJ Open [Category] SARS, 임상, [키워드] acute phase Admission adult intensive & approved autophagy calory cellular clinical trials Critical Critical care defined dietetics discharge Ethics French functional Hospital-acquired infection hypothesised ICU ICUs Impact include Intensive intensive care Invasive mechanical ventilation management mechanically ventilated patient mechanism metabolic pathway Mortality multicentre nutrition & Open-label outcome outcomes parallel group parallel-group Patient peer-reviewed positive primary end-point primary endpoints Protein protein targets randomised receiving recent Restricting Result secondary Shock submitted Support target therapy Trial vasoactive amine Ventilated [DOI] 10.1136/bmjopen-2020-045041 PMC 바로가기 [Article Type] Randomized Controlled Trial
The interplay of SARS-CoV-2 and Clostridioides difficile infectionSpecial Report Published on 2021-04-132022-10-31 Journal: Future Microbiology [Category] COVID-19, MERS, SARS, [키워드] Abstract addition alteration antibiotic Antibiotics appear changed Clostridioide Clostridioides difficile Clostridioides difficile infection Colitis complications COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 symptom diarrhea Donor Gastrointestinal symptom high mortality high risk hospital Hospital-acquired infection incidence Infection measure Microbiome multisystemic pandemic Potential reduce SARS-CoV-2 screened Stool syndrome tested Therapies Transmissibility turn with COVID-19 [DOI] 10.2217/fmb-2020-0275 PMC 바로가기 [Article Type] Special Report
The impact of universal face masking and enhanced hand hygiene for COVID-19 disease prevention on the incidence of hospital-acquired infections in a Taiwanese hospitalArticle Published on 2021-03-012023-07-13 Journal: International Journal of Infectious Diseases [Category] SARS, [키워드] Coronavirus disease 2019 Hospital-acquired infection Multidrug-resistant organism [DOI] 10.1016/j.ijid.2020.12.072 PMC 바로가기
On the emergence of antibacterial and antiviral copper cold spray coatingsReview Published on 2021-02-242022-10-30 Journal: Journal of Biological Engineering [Category] COVID-19, [키워드] Analysis Antimicrobial surfaces Antipathogenic mechanisms Antiviral Atomic ion diffusion pathways Biocidal contact killing biomaterials Cold Spray concerning consolidation Contact copper COVID-19 debate described diffusion Hospital-acquired infection inactivation infectious agent kill literature review Microstructures oligodynamic Pandemics pathogen pathogenic agent Pathogens pathway protection provided responsible secondary transmission Spread Transmission Viricidal contact inactivation [DOI] 10.1186/s13036-021-00256-7 PMC 바로가기 [Article Type] Review
Community-acquired and hospital-acquired respiratory tract infection and bloodstream infection in patients hospitalized with COVID-19 pneumoniaResearch Published on 2021-01-182022-10-30 Journal: Journal of Intensive Care [Category] COVID-19, [키워드] acute lung injury Administered Antifungal treatment Antigen Bacterial Bacterial infection Bacterial infections Bacterial secondary infections Blood bloodstream clinical evidence Community Complication Course COVID-19 COVID-19 pneumonia patients Culture declined diagnosed diagnostics died evaluated excluded final cohort FIVE Frequency Fungal infection Hospital-acquired infection Hospitalized hospitalized patient ICU patient ICU Patients Infection infections Infectious disease information intensive care IQR male mechanical ventilation median age microbial molecular objective Patient patients patients hospitalized patients with COVID-19 Pneumonia reached required respiratory tract infection Result SARS-CoV-2 SARS-CoV-2-positive patient Secondary infection Sepsis supplementary material Switzerland University Hospital Basel Ventilator-associated pneumonia with COVID-19 [DOI] 10.1186/s40560-021-00526-y PMC 바로가기 [Article Type] Research